Reactome | GATAD2B [nucleoplasm]

GATAD2B [nucleoplasm]

Stable Identifier

R-HSA-3702079

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Transcriptional repressor p66-beta, P66B_HUMAN

Locations in the PathwayBrowser for interactor UniProt:Q8IYF3 TEX11

Expand all

External Reference Information

External Reference

UniProt:Q8WXI9 GATAD2B

Gene Names

GATAD2B, KIAA1150

Chain

chain:1-593

Reference Genes

BioGPS Gene:57459 GATAD2B

COSMIC - genes:GATAD2B GATAD2B

CTD Gene:57459 GATAD2B

dbSNP Gene:57459 GATAD2B

ENSEMBL:ENSG00000143614 GATAD2B

HGNC:30778 GATAD2B

KEGG:hsa:57459 GATAD2B

Monarch:57459 GATAD2B

NCBI Gene:57459 GATAD2B

OMIM:614998 GATAD2B

UCSC:Q8WXI9 GATAD2B

Reference Transcript

Other Identifiers

11724893_at

11724894_at

11724895_at

16693546

225393_PM_at

225393_at

238076_PM_at

238076_at

2436227

2436229

2436230

2436231

2436232

2436233

2436234

2436236

2436237

2436238

2436239

2436240

2436241

2436242

2436243

2436244

2436245

2436247

2436248

2436269

2436274

2436275

2436276

2436277

46443_at

57459

64410_at

68606_at

7920341

A_19_P00324786

A_23_P386509

A_33_P3323822

GE53798

GO:0000122

GO:0000781

GO:0000785

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006325

GO:0006338

GO:0006355

GO:0008270

GO:0016581

GO:0016607

GO:0031492

GO:0032991

GO:0042659

GO:0043565

GO:0045892

GO:0045893

GO:0046872

GO:2000736

HMNXSV003023369

Hs.44772.0.A1_3p_at

Hs.4779.1.A1_3p_at

ILMN_1766359

PH_hs_0000486

TC01003278.hg

Participates

as an input of

GATAD2B is SUMOylated (Homo sapiens)

as a candidate of

(GATAD2A, GATAD2B) [nucleoplasm] (Homo sapiens)

Other forms of this molecule

monoSUMO1-K33 GATAD2B [nucleoplasm]

Inferred To

dcp-66 [nucleoplasm] (Caenorhabditis elegans)

gatad2b [nucleoplasm] (Xenopus tropicalis)

Gatad2b [nucleoplasm] (Mus musculus)

Gatad2b [nucleoplasm] (Rattus norvegicus)

GATAD2B [nucleoplasm] (Bos taurus)

GATAD2B [nucleoplasm] (Canis familiaris)

GATAD2B [nucleoplasm] (Gallus gallus)

GATAD2B [nucleoplasm] (Sus scrofa)

simj [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

XP_047282073.1, XP_054193790.1, NP_065750.1

OpenTargets

ENSG00000143614

ENSEMBL

ENSP00000489184, ENST00000576342, ENSP00000458280, ENSG00000261992, ENSP00000357644, ENSG00000143614, ENST00000368655, ENST00000634544

GeneCards

GATAD2B

HPA

ENSG00000143614-GATAD2B

PRO

Q8WXI9

Pharos - Targets

Q8WXI9

GlyGen

Q8WXI9

Orphanet

GATAD2B

Interactors (48)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.892	11
UniProt:Q92769 HDAC2	2	HDAC2 [nucleoplasm] (R-HSA-205135) monoSUMO1-K462-HDAC2 [nucleoplasm] (R-HSA-4615958)	0.837	7
UniProt:Q16576 RBBP7	1	RBBP7 [nucleoplasm] (R-HSA-212227)	0.788	8
UniProt:Q09028 RBBP4	1	RBBP4 [nucleoplasm] (R-HSA-212223)	0.788	7
UniProt:O14519 CDK2AP1	1	CDK2AP1 [nucleoplasm] (R-HSA-9940397)	0.788	7
UniProt:O95983 MBD3	1	MBD3 [nucleoplasm] (R-HSA-4657010)	0.742	7
UniProt:O43741 PRKAB2	3	PRKAB2 [cytosol] (R-HSA-200413) PRKAB2 [nucleoplasm] (R-HSA-164096) PRKAB2 [endoplasmic reticulum lumen] (R-HSA-9931271)	0.666	4
UniProt:Q13077 TRAF1	3	TRAF1 [cytosol] (R-HSA-5634163) TRAF1(1-163) [cytosol] (R-HSA-5634199) TRAF1(164-416) [cytosol] (R-HSA-5634204)	0.666	4
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.643	3
UniProt:O94776 MTA2	1	MTA2 [nucleoplasm] (R-HSA-4657009)	0.643	6
UniProt:Q9NRI5 DISC1			0.632	3
UniProt:O95365 ZBT7A			0.567	4
UniProt:P14373 TRIM27	2	TRIM27 [cytosol] (R-HSA-8851002) TRIM27 [nucleoplasm] (R-HSA-2997690)	0.556	3
UniProt:Q08379 GOLGA2	3	p-S37-GOLGA2 [Golgi membrane] (R-HSA-2172179) GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-2167933) GOLGA2 [Golgi membrane] (R-HSA-6808764)	0.556	3
UniProt:Q14192 FHL2	1	FHL2 [nucleoplasm] (R-HSA-561161)	0.556	3
UniProt:P55273 CDKN2D	1	CDKN2D [cytosol] (R-HSA-182580)	0.556	3
UniProt:P0C264 SBK3			0.556	3
UniProt:Q86UR1-2 NOXA1			0.556	3
UniProt:Q9Y4H4 GPSM3	1	GPSM3 [cytosol] (R-HSA-8949486)	0.556	3
UniProt:Q9Y5B8 NME7	1	NME7 [cytosol] (R-HSA-6806880)	0.556	3
UniProt:Q8N6Y0 USBP1			0.556	3
UniProt:Q8IYF3 TEX11			0.556	3
UniProt:Q13137 CACO2			0.556	3
UniProt:Q8NHQ1 CEP70	1	CEP70 [cytosol] (R-HSA-380257)	0.556	3
UniProt:Q8N5A5-2 ZGPAT			0.556	3
UniProt:Q96KN7 RPGR1			0.556	3
UniProt:Q9NPG2 NGB	1	NGB [cytosol] (R-HSA-5216004)	0.556	3
UniProt:P15056 BRAF	20	BRAF(1-380)-MACF1(600-7388)fusion [cytosol] (R-HSA-6802402) p-BRAF(1-380)-MACF1(600-7388) fusion [cytosol] (R-HSA-6802536) BRAF E501G [cytosol] (R-HSA-9651132) BRAF D594N [cytosol] (R-HSA-6802299) BRAF D638E [cytosol] (R-HSA-9651125) BRAF G596R [cytosol] (R-HSA-6802385) BRAF D594V [cytosol] (R-HSA-6802305) BRAF G596V [cytosol] (R-HSA-9651138) BRAF G466E [cytosol] (R-HSA-6802374) BRAF D594G [cytosol] (R-HSA-6802295) BRAF L505H [cytosol] (R-HSA-9648845) BRAF F595L [cytosol] (R-HSA-6802316) BRAF L597V [cytosol] (R-HSA-6802397) BRAF G464E [cytosol] (R-HSA-6802369) BRAF N581D [cytosol] (R-HSA-9651152) BRAF E586K [cytosol] (R-HSA-6802308) BRAF V600K [cytosol] (R-HSA-6802502) BRAF A246P [cytosol] (R-HSA-9651123) BRAF G469V [cytosol] (R-HSA-9648620) BRAF T244P [cytosol] (R-HSA-9651165)	0.553	3
UniProt:Q9HCI5 MAGE1			0.527	2
UniProt:P68400 CSNK2A1	2	CSNK2A1 [cytosol] (R-HSA-201713) CSNK2A1 [nucleoplasm] (R-HSA-6805057)	0.527	2
UniProt:Q8TDI0 CHD5	1	CHD5 [nucleoplasm] (R-HSA-9940392)	0.527	4
UniProt:Q9UHF7 TRPS1			0.527	2
UniProt:P19784 CSNK2A2	2	CSNK2A2 [cytosol] (R-HSA-201721) CSNK2A2 [nucleoplasm] (R-HSA-6805065)	0.527	2
UniProt:Q12873 CHD3	2	CHD3 [nucleoplasm] (R-HSA-4657012) monoSUMO1-K1971-CHD3 [nucleoplasm] (R-HSA-8956372)	0.527	5
UniProt:Q9H3M7 TXNIP	2	TXNIP [cytosol] (R-HSA-1250246) TXNIP [nucleoplasm] (R-HSA-9617747)	0.527	2
UniProt:Q14839 CHD4	1	CHD4 [nucleoplasm] (R-HSA-3702078)	0.527	5
UniProt:O96006 ZBED1	1	ZBED1 [nucleoplasm] (R-HSA-8956376)	0.527	2
UniProt:Q13330 MTA1	2	MTA1 [nucleoplasm] (R-HSA-3465550) polySUMO2,3-K509-MTA1 [nucleoplasm] (R-HSA-3465537)	0.527	4
UniProt:Q9UBB5 MBD2	1	MBD2 [nucleoplasm] (R-HSA-427367)	0.527	4
UniProt:Q15274 QPRT	1	QPRT [cytosol] (R-HSA-197212)	0.527	2
UniProt:Q8WWY6 MBD3L1	1	MBD3L1 [nucleoplasm] (R-HSA-9940391)	0.527	3
UniProt:Q86UZ6 ZBT46			0.527	2
UniProt:Q9P2Y4 ZN219			0.527	4
UniProt:Q96KM6 ZNF512B	1	ZNF512B [cytosol] (R-HSA-9715175)	0.527	3
UniProt:Q9HCH3 CPNE5			0.527	2
UniProt:Q93045 STMN2	1	STMN2 [cytosol] (R-HSA-9696513)	0.527	2
UniProt:Q9BTC8 MTA3	1	MTA3 [nucleoplasm] (R-HSA-4657013)	0.527	4
UniProt:Q17R98 ZNF827	1	ZNF827 [nucleoplasm] (R-HSA-9941663)	0.499	2

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