DNM2 [lysosomal membrane]

Stable Identifier
R-HSA-2980840
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
lysosomal membrane
Synonyms
Dynamin-2
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P50570 DNM2
Gene Names
DNM2, DYN2
Chain
chain:1-870
Reference Genes
BioGPS Gene:1785 DNM2
COSMIC (genes):DNM2 DNM2
CTD Gene:1785 DNM2
dbSNP Gene:1785 DNM2
ENSEMBL:ENSG00000079805 DNM2
ENSEMBL:ENSG00000079805.19 DNM2
HGNC:2974 DNM2
KEGG Gene (Homo sapiens):1785 DNM2
Monarch:1785 DNM2
NCBI Gene:1785 DNM2
OMIM:602378 DNM2
UCSC:P50570 DNM2
Reference Transcript
Other Identifiers
11735759_a_at
11741014_x_at
11749116_a_at
1785
202253_PM_s_at
202253_s_at
32622_at
3820759
3820760
3820771
3820777
3820779
3820780
3820781
3820782
3820784
3820786
3820789
3820795
3820797
3820803
3820809
3820813
3820816
3820818
3820820
3820821
3820825
3820827
3820828
3820830
3820831
3820832
8025741
A_23_P407074
GE57744
GO:0000086
GO:0000139
GO:0000166
GO:0000278
GO:0001891
GO:0002376
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005737
GO:0005794
GO:0005829
GO:0005856
GO:0005874
GO:0005886
GO:0005905
GO:0005925
GO:0006351
GO:0006355
GO:0006892
GO:0006897
GO:0006898
GO:0006909
GO:0007165
GO:0008017
GO:0008092
GO:0012501
GO:0014069
GO:0016020
GO:0016192
GO:0016787
GO:0017124
GO:0019886
GO:0019899
GO:0023052
GO:0030154
GO:0030426
GO:0030496
GO:0030516
GO:0030666
GO:0030670
GO:0031410
GO:0031623
GO:0033572
GO:0042995
GO:0043065
GO:0043226
GO:0045202
GO:0045211
GO:0045893
GO:0048488
GO:0048489
GO:0048812
GO:0048856
GO:0061024
GO:0070062
GO:0070161
GO:0098793
GO:1903526
HMNXSV003025647
ILMN_1656822
ILMN_2339377
L36983_at
PH_hs_0025257
TC19002623.hg
g4826699_3p_a_at
p33942
Participates
as a candidate of
Other forms of this molecule
DNM2 [Golgi membrane]
DNM2 [cytosol]
DNM2 [endocytic vesicle membrane]
DNM2 [plasma membrane]
Inferred To
DNM2 [lysosomal membrane] (Bos taurus)
DNM2 [lysosomal membrane] (Caenorhabditis elegans)
DNM2 [lysosomal membrane] (Canis familiaris)
DNM2 [lysosomal membrane] (Drosophila melanogaster)
DNM2 [lysosomal membrane] (Gallus gallus)
DNM2 [lysosomal membrane] (Mus musculus)
DNM2 [lysosomal membrane] (Rattus norvegicus)
DNM2 [lysosomal membrane] (Sus scrofa)
dnm2 [lysosomal membrane] (Danio rerio)
dnm2 [lysosomal membrane] (Xenopus tropicalis)
Cross References
RefSeq
OpenTargets
ZINC - Substances
ZINC target
PRO
PDB
IntEnz
HPA
GeneCards
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (32)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P62993 GRB2  1 0.918 9
 UniProt:Q9Y5X1 SNX9  3 0.807 8
 UniProt:Q99962 SH3GL2  4 0.722 4
 UniProt:P49418 AMPH  1 0.713 3
 UniProt:Q15811 ITSN1  1 0.713 3
 UniProt:Q14247 CTTN  2 0.645 5
 UniProt:O76064 RNF8  1 0.556 3
 UniProt:Q8NFF5-2 FLAD1      0.556 3
 UniProt:P57075-2 UBASH3A      0.556 3
 UniProt:O00560 SDCBP  3 0.556 3
 UniProt:Q9BUZ4 TRAF4      0.556 3
 IntAct:EBI-22313194 CCSB ORF ID      0.556 3
 UniProt:P54646 PRKAA2  4 0.556 3
 UniProt:O95817 BAG3  1 0.556 3
 UniProt:P47897 QARS1  2 0.556 3
 UniProt:Q15436 SEC23A  4 0.556 3
 UniProt:P22392 NME2  4 0.525 2
 UniProt:Q9P0V3 SH3BP4  1 0.524 3
 UniProt:Q12965 MYO1E      0.524 2
 UniProt:Q9UNF0 PACSIN2  1 0.524 4
 UniProt:Q96B97 SH3KBP1  3 0.524 5
 UniProt:O14645 IDLC      0.508 2
 UniProt:Q8N157 AHI1  1 0.499 2
 UniProt:Q96RU3 FNBP1  1 0.499 2
 UniProt:O75791 GRAP2  1 0.488 2
 UniProt:Q08379 GOLGA2  3 0.488 2
 UniProt:P50570 DNM2  5 0.488 2
 UniProt:P98170 XIAP  3 0.488 2
 UniProt:Q96HA8 NTAQ1      0.488 2
 ChEBI:18348 1-PHOSPHATIDYL-1D-MYO-INOSITOL 4,5-BISPHOSPHATE      0.462 2
 ChEBI:16618 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,4,5-TRISPHOSPHATE      0.462 2
 ChEBI:16851 1-PHOSPHATIDYL-1D-MYO-INOSITOL 3,5-BISPHOSPHATE      0.462 2
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