Reactome | SNX9 [cytoplasmic vesicle membrane]

SNX9 [cytoplasmic vesicle membrane]

Stable Identifier

R-HSA-432990

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytoplasmic vesicle membrane

Synonyms

Sorting nexin-9, SNX9_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9Y5X1 SNX9

Gene Names

SNX9, SH3PX1, SH3PXD3A

Chain

chain:1-595

Reference Genes

BioGPS Gene:51429 SNX9

COSMIC (genes):SNX9 SNX9

CTD Gene:51429 SNX9

dbSNP Gene:51429 SNX9

ENSEMBL:ENSG00000130340 SNX9

ENSEMBL:ENSG00000130340.17 SNX9

HGNC:14973 SNX9

KEGG Gene (Homo sapiens):51429 SNX9

Monarch:51429 SNX9

NCBI Gene:51429 SNX9

OMIM:605952 SNX9

UCSC:Q9Y5X1 SNX9

Reference Transcript

RefSeq:NM_016224.4 SNX9

Other Identifiers

11731784_a_at

11746543_a_at

11756208_a_at

17014091

223027_PM_at

223027_at

223028_PM_s_at

223028_s_at

2933332

2933338

2933339

2933341

2933346

2933349

2933353

2933354

2933355

2933358

2933362

2933364

2933366

2933368

2933371

2933373

2933375

2933379

2933380

2933381

2933382

2933383

2933384

2933385

2933386

2933387

46285_at

51429

51748_at

65579_at

8122986

A_23_P214789

GE58706

GO:0000278

GO:0000281

GO:0000910

GO:0001726

GO:0005515

GO:0005545

GO:0005576

GO:0005615

GO:0005737

GO:0005794

GO:0005802

GO:0005829

GO:0005856

GO:0005886

GO:0005905

GO:0006886

GO:0006897

GO:0006898

GO:0007010

GO:0007049

GO:0008289

GO:0015031

GO:0016020

GO:0016192

GO:0016197

GO:0030136

GO:0030163

GO:0030659

GO:0030838

GO:0031410

GO:0031625

GO:0032437

GO:0035091

GO:0036089

GO:0036211

GO:0042802

GO:0042803

GO:0042995

GO:0043226

GO:0043547

GO:0045296

GO:0045860

GO:0051044

GO:0051301

GO:0051641

GO:0060988

GO:0061024

GO:0065003

GO:0070062

GO:0071933

GO:0097320

GO:0098793

GO:1900242

HMNXSV003058447

Hs.7905.0.S2_3p_at

ILMN_1726366

PH_hs_0000815

TC06001126.hg

TC06003152.hg

g13477130_3p_a_at

Participates

as a candidate of

Golgi-associated Vesicle Cargo [cytoplasmic vesicle membrane] (Homo sapiens)

Other forms of this molecule

SNX9 [cytosol]

SNX9 [Golgi membrane]

Inferred To

lst-4 [cytoplasmic vesicle membrane] (Caenorhabditis elegans)

snx9 [cytoplasmic vesicle membrane] (Xenopus tropicalis)

SH3PX1 [cytoplasmic vesicle membrane] (Drosophila melanogaster)

SNX9 [cytoplasmic vesicle membrane] (Bos taurus)

SNX9 [cytoplasmic vesicle membrane] (Canis familiaris)

SNX9 [cytoplasmic vesicle membrane] (Danio rerio)

SNX9 [cytoplasmic vesicle membrane] (Gallus gallus)

SNX9 [cytoplasmic vesicle membrane] (Mus musculus)

SNX9 [cytoplasmic vesicle membrane] (Sus scrofa)

Snx9 [cytoplasmic vesicle membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_057308.1

OpenTargets

ENSG00000130340

HPA

ENSG00000130340-SNX9

GeneCards

Q9Y5X1

Ensembl

ENST00000679814, ENSP00000376024, ENSG00000130340, ENSP00000506326, ENST00000392185

PRO

Q9Y5X1

Pharos - Targets

Q9Y5X1

PDB

3DYU, 2RAK, 2RAI, 3DYT, 2RAJ, 3LGE, 7OJ9

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P50570 DNM2	5	DNM2 [Golgi membrane] (R-HSA-2980842) DNM2 [cytosol] (R-HSA-2213180) DNM2 [endocytic vesicle membrane] (R-HSA-2029000) DNM2 [lysosomal membrane] (R-HSA-2980840) DNM2 [plasma membrane] (R-HSA-2984201)	0.807	8
UniProt:Q05193 DNM1	3	DNM1 [cytosol] (R-HSA-2213182) DNM1 [lysosomal membrane] (R-HSA-196150) DNM1 [plasma membrane] (R-HSA-177488)	0.775	5
UniProt:Q96J02 ITCH	2	Ub-C871-ITCH [cytosol] (R-HSA-8864515) ITCH [cytosol] (R-HSA-975995)	0.623	7
UniProt:P42768 WAS	2	WAS [cytosol] (R-HSA-201879) p-Y291-WAS [cytosol] (R-HSA-2197668)	0.573	2
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:O00401 WASL	4	WASL [plasma membrane] (R-HSA-203010) WASL [endocytic vesicle membrane] (R-HSA-535012) N-WASP [cytosol] (R-HSA-201873) p-Y256-WASL [cytosol] (R-HSA-2197672)	0.524	2
UniProt:P48023 FASLG	1	FASLG(1-281) [extracellular region] (R-HSA-66212)	0.524	2
UniProt:Q07889 SOS1	3	p-4S-SOS1 [cytosol] (R-HSA-109821) SOS1 [plasma membrane] (R-HSA-983559) SOS1 [cytosol] (R-HSA-64847)	0.524	2
UniProt:P0CG48 UBC	20	UBC(381-456) [endocytic vesicle membrane] (R-HSA-939218) UBC(533-608) [endocytic vesicle membrane] (R-HSA-939220) UBC(609-684) [endocytic vesicle membrane] (R-HSA-939223) UBC(457-532) [endocytic vesicle membrane] (R-HSA-939195) UBC(153-228) [endocytic vesicle membrane] (R-HSA-939194) UBC(305-380) [endocytic vesicle membrane] (R-HSA-939228) UBC(229-304) [endocytic vesicle membrane] (R-HSA-939177) UBC(77-152) [endocytic vesicle membrane] (R-HSA-939210) UBC(1-76) [endocytic vesicle membrane] (R-HSA-939245) Ub-565-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783166) Ub-337-UBC(305-380) [mitochondrial outer membrane] (R-HSA-6783121) Ub-185-UBC(153-228) [mitochondrial outer membrane] (R-HSA-6783154) Ub-261-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783028) Ub-413-UBC(381-456) [mitochondrial outer membrane] (R-HSA-6783061) Ub-109-UBC(77-152) [mitochondrial outer membrane] (R-HSA-6783158) Ub-641-UBC(609-684) [mitochondrial outer membrane] (R-HSA-6783182) Ub-33-UBC(1-76) [mitochondrial outer membrane] (R-HSA-6783073) Ub-489-UBC(457-532) [mitochondrial outer membrane] (R-HSA-6783078) Ub-291-UBC(229-304) [mitochondrial outer membrane] (R-HSA-6783193) Ub-595-UBC(533-608) [mitochondrial outer membrane] (R-HSA-6783130)	0.499	2
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	7

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