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NME2 [secretory granule lumen]
Stable Identifier
R-HSA-6803277
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
non-metastatic cells 2, protein (NM23B) expressed in, Nucleoside diphosphate kinase B, nm23-H2, Nucleoside diphosphate kinase B , NDK B, NDP kinase B, C-myc purine-binding transcription factor PUF
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
NME2 [secretory granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P22392 NME2
Gene Names
NME2, NM23B
Chain
chain:1-152
Reference Genes
BioGPS Gene:4831 NME2
BioGPS Gene:654364 NME2
COSMIC (genes):NME2 NME2
CTD Gene:4831 NME2
CTD Gene:654364 NME2
dbSNP Gene:4831 NME2
dbSNP Gene:654364 NME2
ENSEMBL:ENSG00000243678.12 NME2
HGNC:7850 NME2
KEGG Gene (Homo sapiens):4831 NME2
KEGG Gene (Homo sapiens):654364 NME2
Monarch:4831 NME2
Monarch:654364 NME2
NCBI Gene:4831 NME2
NCBI Gene:654364 NME2
OMIM:156491 NME2
UCSC:P22392 NME2
Reference Transcript
RefSeq:NM_001018136.2 NME2
RefSeq:NM_001018138.1 NME2
RefSeq:NM_001018137.2 NME2
RefSeq:NM_002512.3 NME2
RefSeq:NM_001018139.2 NME2
Other Identifiers
11718294_s_at
1980_s_at
201268_PM_at
201268_at
33415_at
3434301
3434305
3434307
3726961
3726962
3726964
3726965
3726966
3726967
3726968
3726969
3726971
3726974
3726975
4831
8180386
8180387
8180388
8180389
A_23_P141405
GE61684
GO:0000166
GO:0001726
GO:0003677
GO:0003713
GO:0003824
GO:0004550
GO:0004673
GO:0005515
GO:0005524
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005829
GO:0006165
GO:0006183
GO:0006228
GO:0006241
GO:0006351
GO:0006355
GO:0007155
GO:0007229
GO:0009117
GO:0009142
GO:0012501
GO:0016301
GO:0016310
GO:0016740
GO:0018106
GO:0019003
GO:0023052
GO:0030027
GO:0030154
GO:0031410
GO:0034774
GO:0036211
GO:0042981
GO:0042995
GO:0043066
GO:0043226
GO:0045618
GO:0045682
GO:0045893
GO:0045944
GO:0046872
GO:0048471
GO:0048856
GO:0050679
GO:0051880
GO:0055086
GO:0070062
GO:0071944
GO:0140096
GO:0140110
GO:1901135
GO:1904813
HMNXSV003052386
ILMN_1657884
ILMN_1662905
ILMN_1694012
ILMN_2234873
ILMN_2414007
TC17002881.hg
g4505408_3p_s_at
Participates
as a member of
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
Other forms of this molecule
NME2 [cytosol]
NME2 [extracellular region]
NME2 [ficolin-1-rich granule lumen]
Inferred To
ndk-1 [secretory granule lumen]
(Caenorhabditis elegans)
nme2 [secretory granule lumen]
(Xenopus tropicalis)
NME2 [secretory granule lumen]
(Bos taurus)
NME2 [secretory granule lumen]
(Canis familiaris)
NME2 [secretory granule lumen]
(Danio rerio)
NME2 [secretory granule lumen]
(Dictyostelium discoideum)
NME2 [secretory granule lumen]
(Drosophila melanogaster)
NME2 [secretory granule lumen]
(Gallus gallus)
NME2 [secretory granule lumen]
(Mus musculus)
NME2 [secretory granule lumen]
(Plasmodium falciparum)
NME2 [secretory granule lumen]
(Rattus norvegicus)
NME2 [secretory granule lumen]
(Saccharomyces cerevisiae)
NME2 [secretory granule lumen]
(Schizosaccharomyces pombe)
NME2 [secretory granule lumen]
(Sus scrofa)
Cross References
RefSeq
NP_001018146.1
,
NP_001018148.1
,
NP_001018149.1
,
NP_001018147.1
,
NP_002503.1
OpenTargets
ENSG00000243678
IntEnz
2.7.4.6
,
2.7.13.3
GeneCards
P22392
HPA
ENSG00000243678-NME2
ZINC target
P22392
Ensembl
ENST00000503064
,
ENST00000393190
,
ENSP00000421064
,
ENSP00000425581
,
ENSP00000426976
,
ENSP00000426901
,
ENST00000514264
,
ENSG00000243678
,
ENST00000513177
,
ENST00000512737
,
ENSP00000376886
PRO
P22392
Pharos - Targets
P22392
HMDB Protein
HMDBP00112
PDB
1NUE
,
3BBC
,
3BBB
,
7KPF
,
3BBF
,
1NSK
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P50570 DNM2
5
DNM2 [Golgi membrane]
(R-HSA-2980842)
DNM2 [cytosol]
(R-HSA-2213180)
DNM2 [plasma membrane]
(R-HSA-2984201)
DNM2 [lysosomal membrane]
(R-HSA-2980840)
DNM2 [endocytic vesicle membrane]
(R-HSA-2029000)
0.525
2
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