Reactome | OS9 [endoplasmic reticulum membrane]

OS9 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-1022132

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Protein OS-9, OS9_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q13438 OS9

Gene Names

OS9

Chain

signal peptide:1-25, chain:26-667

Reference Genes

BioGPS Gene:10956 OS9

COSMIC (genes):OS9 OS9

CTD Gene:10956 OS9

dbSNP Gene:10956 OS9

ENSEMBL:ENSG00000135506 OS9

ENSEMBL_homo_sapiens_GENE:ENSG00000135506.17 OS9

HGNC:16994 OS9

KEGG Gene (Homo sapiens):10956 OS9

Monarch:10956 OS9

NCBI Gene:10956 OS9

OMIM:609677 OS9

UCSC:Q13438 OS9

Reference Transcript

Other Identifiers

10956

11718989_s_at

11718990_x_at

11751704_a_at

11752346_a_at

11752347_x_at

11752689_a_at

16753125

200714_PM_x_at

200714_x_at

215399_PM_s_at

215399_s_at

3418437

3418438

3418440

3418442

3418443

3418445

3418451

3418452

3418454

3418457

3418459

3418460

3418461

3418462

3418463

3418465

3418466

3418467

3418469

3418471

3418473

3418474

3418475

3418476

3418477

36996_at

7956593

84062_at

87781_s_at

A_14_P112435

A_14_P137588

A_24_P270166

GE739476

GE753288

GO:0000836

GO:0002020

GO:0005515

GO:0005783

GO:0005788

GO:0005789

GO:0006511

GO:0006605

GO:0006621

GO:0006886

GO:0016567

GO:0023052

GO:0030163

GO:0030246

GO:0030433

GO:0030968

GO:0030970

GO:0034976

GO:0036211

GO:0043226

GO:1904153

HMNXSV003038094

Hs.76228.2.A1_3p_s_at

ILMN_2361807

PH_hs_0004399

TC12000539.hg

U41635_at

Participates

as a member of

OS9/ERLEC1 [endoplasmic reticulum quality control compartment] (Homo sapiens)

as a component of

OS9:SEL1:ERAD E3 ligases:DERL2 [endoplasmic reticulum membrane] (Homo sapiens)

Inferred To

OS9 [endoplasmic reticulum membrane] (Bos taurus)

OS9 [endoplasmic reticulum membrane] (Caenorhabditis elegans)

OS9 [endoplasmic reticulum membrane] (Canis familiaris)

OS9 [endoplasmic reticulum membrane] (Dictyostelium discoideum)

OS9 [endoplasmic reticulum membrane] (Mus musculus)

OS9 [endoplasmic reticulum membrane] (Rattus norvegicus)

OS9 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)

OS9 [endoplasmic reticulum membrane] (Sus scrofa)

zgc:153838 [endoplasmic reticulum membrane] (Danio rerio)

os9 [endoplasmic reticulum membrane] (Xenopus tropicalis)

Cross References

RefSeq

NP_006803.1, NP_001248351.1, NP_001017958.1, NP_001017957.1, NP_001248350.1, NP_001248349.1, NP_001017956.1, NP_001248352.1

OpenTargets

ENSG00000135506

GeneCards

Q13438

HPA

ENSG00000135506-OS9

Ensembl

ENSP00000447866, ENST00000257966, ENSP00000257966, ENST00000439210, ENSP00000373794, ENST00000435406, ENSP00000407360, ENSP00000389632, ENSG00000135506, ENSP00000373798, ENST00000315970, ENST00000552285, ENSP00000318165, ENST00000551035, ENST00000389142, ENSP00000450010, ENST00000389146

PRO

Q13438

Pharos - Targets

Q13438

PDB

3AIH

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9UBV2 SEL1L	1	SEL1L [endoplasmic reticulum membrane] (R-HSA-1911545)	0.823	11
UniProt:Q16665 HIF1A	7	HN-HIF1A [cytosol] (R-HSA-1234110) 2xHP-HIF1A [nucleoplasm] (R-HSA-1234105) 2xHP-HIF1A [cytosol] (R-HSA-1234131) p-Y565,S797-HIF1A [cytosol] (R-HSA-9634700) p-Y565-HIF1A [cytosol] (R-HSA-8857584) HIF1A [cytosol] (R-HSA-1234102) HIF1A [nucleoplasm] (R-HSA-1234135)	0.649	9
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.623	3
UniProt:Q86TM6 SYVN1	1	SYVN1(1-617) [endoplasmic reticulum membrane] (R-HSA-535496)	0.597	9
UniProt:P14625 HSP90B1	4	HSP90B1 [endocytic vesicle lumen] (R-HSA-3221623) HSP90B1 [extracellular region] (R-HSA-3221653) p-HSP90B1 [endoplasmic reticulum lumen] (R-HSA-8957016) HSP90B1 [endoplasmic reticulum lumen] (R-HSA-981545)	0.527	3
UniProt:P0DTC8 8	2	8 [extracellular region] (R-COV-9755410) 8 [endoplasmic reticulum lumen] (R-COV-9727283)	0.527	2
UniProt:P04578 env	7	Surface protein gp120 (P04578) [cytosol] (R-HIV-189269) Transmembrane protein gp41 (P04578) [cytosol] (R-HIV-189359) Glycosylated Envelope glycoprotein gp160 [Golgi membrane] (R-HIV-3149443) Envelope glycoprotein gp160 [endoplasmic reticulum membrane] (R-HIV-189343) Transmembrane protein gp41 [viral envelope] (R-HIV-171195) ENV [viral envelope] (R-HIV-173439) Surface protein gp120 [viral envelope] (R-HIV-171211)	0.462	2