HS(5)-AGRN [plasma membrane]

Stable Identifier
R-HSA-2076642
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
AGRN, Agrin, AGRIN_HUMAN
Locations in the PathwayBrowser
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External Reference Information
External Reference
UniProt:O00468 AGRN
Gene Names
AGRN, AGRIN
Chain
signal peptide:1-29, chain:30-2068, chain:30-1102, chain:1103-2068, chain:1103-1863, chain:1864-2068
Reference Genes
BioGPS Gene:375790 O004686
COSMIC (genes):AGRN AGRN
CTD Gene:375790 O004686
dbSNP Gene:375790 O004686
ENSEMBL:ENSG00000188157 AGRN
HGNC:329 O004686
KEGG:hsa:375790 O004686
Monarch:375790 O004686
NCBI Gene:375790 O004686
OMIM:103320 O004686
UCSC:O00468 O004686
Reference Transcript
Participates
as a member of
Other forms of this molecule
HS(4)-AGRN [plasma membrane]
HS(6)-AGRN [plasma membrane]
HS(2)-AGRN [plasma membrane]
HS(1)-AGRN [plasma membrane]
HS(3)-AGRN [plasma membrane]
AGRN(30-2045) [extracellular region]
AGRN(30-2045) [Golgi lumen]
XylS-AGRN(30-2045) [Golgi lumen]
Gal-Xyl-AGRN [Golgi lumen]
Gal-Gal-Xyl-AGRN [Golgi lumen]
GlcA-Gal-Gal-Xyl-AGRN [Golgi lumen]
HS(2)-AGRN [Golgi lumen]
HS(3)-AGRN [Golgi lumen]
HS(1)-AGRN [Golgi lumen]
Heparan(4)-AGRN [Golgi lumen]
Heparan(3)-AGRN [Golgi lumen]
Heparan(2)-AGRN [Golgi lumen]
Heparan(1)-AGRN [Golgi lumen]
Heparan-AGRN [Golgi lumen]
HS(4)-AGRN [Golgi lumen]
HS(5)-AGRN [Golgi lumen]
HS(6)-AGRN [Golgi lumen]
HS(6)-AGRN [lysosomal lumen]
AGRN(30-2045) [lysosomal lumen]
Inferred To
Homologues of HS(5)-AGRN [plasma membrane] (Caenorhabditis elegans)
AGRN [plasma membrane] (Bos taurus)
AGRN [plasma membrane] (Canis familiaris)
AGRN [plasma membrane] (Sus scrofa)
SP2353 [plasma membrane] (Drosophila melanogaster)
itx-1 [plasma membrane] (Caenorhabditis elegans)
HS(5)-AGRN [plasma membrane] (Caenorhabditis elegans)
HS(5)-AGRN [plasma membrane] (Mus musculus)
HS(5)-AGRN [plasma membrane] (Rattus norvegicus)
Modified Residues
Name
O-xylosyl-L-serine (beta-D-IdoA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group) at unknown position
Modification
beta-D-IdoA-(1->4)-alpha-D-GlcNS-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
OpenTargets
ENSEMBL
GeneCards
HPA
PRO
Pharos - Targets
GlyGen
Orphanet
PDB
Interactors (4)
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