Ivo P Touw

 ORCID
https://orcid.org/0000-0002-4773-4074
Reviewed Pathways (2/2)
Date Identifier Pathway Reference
2020-12-12 R-HSA-9674555 Signaling by CSF3 (G-CSF) BibTex
2020-12-12 R-HSA-9705462 Inactivation of CSF3 (G-CSF) signaling BibTex
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Reviewed Reactions (15/37)
Date Identifier Reaction Reference
2020-12-12 R-HSA-9674816 p-Y546,Y584-PTPN11 (in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:SHC:GRB2:PTPN11) dephosphorylates KRAS BibTex
2020-12-12 R-HSA-9674808 CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) BibTex
2020-12-12 R-MMU-9674973 Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds and phosphorylates Shc1, Grb2, Gab2, and Ptpn11 BibTex
2020-12-12 R-HSA-9707977 CSF3 dimer:2xK48polyUb-K655,p-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-Y-SYK:p-HCK:p-TYK2 translocates from the endocytic vesicle membrane to the lysosomal membrane BibTex
2020-12-12 R-HSA-9705738 SOCS1,3 ubiquitinates CSF3R in SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2:CUL5:ELOB:ELOC:RNF7 BibTex
2020-12-12 R-HSA-9705729 SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 binds CUL5, ELOB, ELOC, RNF7 BibTex
2020-12-12 R-MMU-9707972 Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 binds Cul5, EloB, EloC, and Rnf7 BibTex
2020-12-12 R-HSA-9705726 SOCS1,3:p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 is endocytosed BibTex
2020-12-12 R-MMU-9707979 Socs1,3:p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 is endocytosed BibTex
2020-12-12 R-HSA-9705467 SOCS1,3 binds p-4Y-CSF3R:CSF3 dimer:LYN:p-Y-JAK1:p-JAK2:p-SYK:p-HCK:p-TYK2 BibTex
2020-12-12 R-MMU-9705471 Socs1,3 binds p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2 BibTex
2020-12-12 R-HSA-9705466 p-Y-STAT1,3,5 dimer enhances expression of SOCS1 BibTex
2020-12-12 R-MMU-9705455 p-Y-Stat1,3,5 dimer enhances expression of Socs1 BibTex
2020-12-12 R-HSA-9705458 p-Y-STAT1,3,5 dimer enhances expression of SOCS3 BibTex
2020-12-12 R-MMU-9705464 p-Y-Stat1,3,5 dimer enhances expression of Socs3 BibTex
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