Socs1,3 binds p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2

Stable Identifier
R-MMU-9705471
Type
Reaction [binding]
Species
Mus musculus
Compartment
General
SVG |   | PPTX  | SBGN
Socs1,3 binds p-4Y-Csf3r:Csf3 dimer:Lyn:p-Y-Jak1:p-Jak2:p-Syk:p-Hck:p-Tyk2

Socs3 or Socs1 binds phosphotyrosine-729 (phosphotyrosine-728 of isoform 1) of Csf3r (Hermans et al. 2003, van de Geijn et al. 2004, Zhuang et al . 2005).

Literature References
PubMed ID Title Journal Year
15069015 G-CSF receptor truncations found in SCN/AML relieve SOCS3-controlled inhibition of STAT5 but leave suppression of STAT3 intact

van de Geijn, GJ, Gits, J, Aarts, LH, Heijmans-Antonissen, C, Touw, IP

Blood 2004
16033816 Tyrosine 729 of the G-CSF receptor controls the duration of receptor signaling: involvement of SOCS3 and SOCS1

Zhuang, D, Qiu, Y, Haque, SJ, Dong, F

J Leukoc Biol 2005
12468431 Signaling mechanisms coupled to tyrosines in the granulocyte colony-stimulating factor receptor orchestrate G-CSF-induced expansion of myeloid progenitor cells

Hermans, MH, van de Geijn, GJ, Antonissen, C, Gits, J, van Leeuwen, D, Ward, AC, Touw, IP

Blood 2003
Participants
Orthologous Events
Authored
Reviewed
Created
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