Pexophagy

Stable Identifier
R-HSA-9664873
DOI
10.3180/R-HSA-9664873.1
Type
Pathway
Species
Homo sapiens
Compartment
peroxisomal membrane, cytosol
ReviewStatus
5/5
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Pexophagy
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Peroxisomes are cytosolic organelles involved in the catabolism of branched and long-chain fatty acids and in the reduction of reactive oxygen species (ROS). Peroxisomes homeostasis is critical to maintain ROS levels. Consequently, it is important to eliminate dysfunctional peroxisomes. The degradation of peroxisomes by autophagy is known as pexophagy (Katarzyna ZR et al. 2016). Pexophagy can be triggered by a shift in nutrient conditions.
Literature References
PubMed ID Title Journal Year
27068951 Autophagic degradation of peroxisomes in mammals

Subramani, S, Zientara-Rytter, K

Biochem. Soc. Trans. 2016
Participants
Events
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as an event of
Event Information
Go Biological Process
pexophagy (0000425)
Orthologous Events
Pexophagy (Bos taurus)
Pexophagy (Canis familiaris)
Pexophagy (Dictyostelium discoideum)
Pexophagy (Drosophila melanogaster)
Pexophagy (Gallus gallus)
Pexophagy (Mus musculus)
Pexophagy (Rattus norvegicus)
Pexophagy (Saccharomyces cerevisiae)
Pexophagy (Schizosaccharomyces pombe)
Pexophagy (Sus scrofa)
Cross References
BioModels Database
Authored
Varusai, TM  (2019-10-29)
Reviewed
Metzakopian, E  (2019-10-30)
Created
Varusai, TM  (2019-10-28)
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