ATM dimer:PEX5 phosphorylates PEX5

Stable Identifier
R-HSA-9664862
Type
Reaction [transition]
Species
Homo sapiens
Compartment
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When serine/threonine kinase Ataxia telangiectasia mutated protein (ATM) is activated it can phosphorylate Peroxisomal targeting signal 1 receptor protein (PEX5) at Ser141 (Zhang J et al. 2015).

Literature References
PubMed ID Title Journal Year
26344566 ATM functions at the peroxisome to induce pexophagy in response to ROS

Zhang, J, Tripathi, DN, Jing, J, Alexander, A, Kim, J, Powell, RT, Dere, R, Tait-Mulder, J, Lee, JH, Paull, TT, Pandita, RK, Charaka, VK, Pandita, TK, Kastan, MB, Walker, CL

Nat. Cell Biol. 2015
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