ATM:PEX5 translocates from cytosol to peroxisomal membrane

Stable Identifier
R-HSA-9664883
Type
Reaction [transition]
Species
Homo sapiens
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After the binding of Peroxisomal targeting signal 1 receptor (PEX5) and Ataxia telangiectasia mutated protein (ATM), PEX5 recruits the complex to the peroxisomal membrane for the next steps of the degradation process (Zhang J et al. 2015).

Literature References
PubMed ID Title Journal Year
26344566 ATM functions at the peroxisome to induce pexophagy in response to ROS

Zhang, J, Tripathi, DN, Jing, J, Alexander, A, Kim, J, Powell, RT, Dere, R, Tait-Mulder, J, Lee, JH, Paull, TT, Pandita, RK, Charaka, VK, Pandita, TK, Kastan, MB, Walker, CL

Nat. Cell Biol. 2015
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