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MPST [mitochondrial matrix]
Stable Identifier
R-HSA-9012720
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
mitochondrial matrix
Synonyms
3-mercaptopyruvate sulfurtransferase, THTM_HUMAN
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Sulfur amino acid metabolism (Homo sapiens)
Degradation of cysteine and homocysteine (Homo sapiens)
MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST (Homo sapiens)
MPST [mitochondrial matrix] (Homo sapiens)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Homo sapiens)
MPST [mitochondrial matrix] (Homo sapiens)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Homo sapiens)
MPST [mitochondrial matrix] (Homo sapiens)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Homo sapiens)
MPST [mitochondrial matrix] (Homo sapiens)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Homo sapiens)
MPST [mitochondrial matrix] (Homo sapiens)
External Reference Information
External Reference
UniProt:P25325 MPST
Gene Names
MPST, TST2
Chain
initiator methionine:, chain:2-297
Reference Genes
BioGPS Gene:4357 MPST
COSMIC (genes):MPST MPST
CTD Gene:4357 MPST
dbSNP Gene:4357 MPST
ENSEMBL:ENSG00000128309 MPST
HGNC:7223 MPST
KEGG:hsa:4357 MPST
Monarch:4357 MPST
NCBI Gene:4357 MPST
OMIM:602496 MPST
UCSC:P25325 MPST
Reference Transcript
RefSeq:NM_001013436.2 MPST
RefSeq:NM_001130517.2 MPST
RefSeq:XM_005261610.3 MPST
RefSeq:NM_021126.5 MPST
Other Identifiers
11753895_x_at
16929707
203524_PM_s_at
203524_s_at
36124_at
3944621
3944622
3944623
3944625
3944626
3944627
3944628
3944629
3944630
3944631
3944632
3944634
4357
8072777
A_14_P126525
A_23_P132285
GE60432
GO:0000098
GO:0001822
GO:0001889
GO:0003824
GO:0004792
GO:0005515
GO:0005737
GO:0005739
GO:0005759
GO:0006520
GO:0006790
GO:0009440
GO:0009636
GO:0016740
GO:0016783
GO:0016784
GO:0019346
GO:0021510
GO:0042802
GO:0043005
GO:0043226
GO:0045202
GO:0048856
GO:0070062
GO:0070814
HMNXSV003010928
HMNXSV003027885
ILMN_1672879
ILMN_1764596
ILMN_1800096
PH_hs_0013192
PH_hs_0039227
TC22000275.hg
TC22001097.hg
X59434_at
g13489090_3p_s_at
Participates
as an input of
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Homo sapiens)
as an output of
MPST and TXN2 enable the synthesis of disulfanide from CysS248-MPST (Homo sapiens)
Other forms of this molecule
CysS248-MPST [mitochondrial matrix]
Inferred To
mpst [mitochondrial matrix]
(Danio rerio)
mpst [mitochondrial matrix]
(Xenopus tropicalis)
TUM1 [mitochondrial matrix]
(Saccharomyces cerevisiae)
mpst-6 [mitochondrial matrix]
(Caenorhabditis elegans)
MPST [mitochondrial matrix]
(Bos taurus)
MPST [mitochondrial matrix]
(Canis familiaris)
MPST [mitochondrial matrix]
(Dictyostelium discoideum)
MPST [mitochondrial matrix]
(Gallus gallus)
MPST [mitochondrial matrix]
(Mus musculus)
MPST [mitochondrial matrix]
(Plasmodium falciparum)
MPST [mitochondrial matrix]
(Rattus norvegicus)
MPST [mitochondrial matrix]
(Schizosaccharomyces pombe)
MPST [mitochondrial matrix]
(Sus scrofa)
Cross References
Guide to Pharmacology - Targets
1446
ENSEMBL
ENSP00000384812
,
ENSP00000380402
,
ENSP00000342333
,
ENSP00000383950
,
ENST00000404802
,
ENST00000429360
,
ENSG00000128309
,
ENST00000397225
,
ENST00000401419
,
ENST00000341116
,
ENSP00000411719
OpenTargets
ENSG00000128309
GeneCards
MPST
HPA
ENSG00000128309-MPST
PRO
P25325
Pharos - Targets
P25325
GlyGen
P25325
HMDB Protein
HMDBP00781
PDB
3OLH
,
4JGT
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O96006 ZBED1
1
ZBED1 [nucleoplasm]
(R-HSA-8956376)
0.556
3
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