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ATP6AP1 [endosome membrane]
Stable Identifier
R-HSA-5215981
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endosome membrane
Synonyms
V-type proton ATPase subunit S1, VAS1_HUMAN
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
Endosome acidification (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
Iron uptake and transport (Homo sapiens)
Transferrin endocytosis and recycling (Homo sapiens)
ATP6AP1 binds V-ATPase (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
Acidification of Tf:TfR1 containing endosome (Homo sapiens)
V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
ATP6AP1 [endosome membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15904 ATP6AP1
Gene Names
ATP6AP1, ATP6IP1, ATP6S1, VATPS1, XAP3
Chain
signal peptide:1-41, chain:42-470
Reference Genes
BioGPS Gene:537 ATP6AP1
COSMIC (genes):ATP6AP1 ATP6AP1
CTD Gene:537 ATP6AP1
dbSNP Gene:537 ATP6AP1
ENSEMBL:ENSG00000071553 ATP6AP1
HGNC:868 ATP6AP1
KEGG Gene (Homo sapiens):537 ATP6AP1
Monarch:537 ATP6AP1
NCBI Gene:537 ATP6AP1
OMIM:300197 ATP6AP1
UCSC:Q15904 ATP6AP1
Reference Transcript
RefSeq:NM_001183.5 ATP6AP1
RefSeq:XM_011531179.1 ATP6AP1
Other Identifiers
0005890504
11749258_a_at
11754958_s_at
17108354
207809_s_at
35770_at
3996382
3996383
3996384
3996385
3996386
3996388
3996390
3996391
3996392
3996393
3996394
3996395
3996396
3996397
3996398
3996399
3996400
3996401
3996402
3996403
3996405
537
8170882
A_23_P250462
A_24_P74753
D16469_at
GE79783
GO:0000166
GO:0002376
GO:0003674
GO:0005515
GO:0005524
GO:0005575
GO:0005576
GO:0005615
GO:0005622
GO:0005737
GO:0005768
GO:0005783
GO:0005789
GO:0005886
GO:0006464
GO:0006810
GO:0006811
GO:0006879
GO:0007165
GO:0008150
GO:0008286
GO:0010008
GO:0015031
GO:0016020
GO:0016021
GO:0016192
GO:0016469
GO:0017137
GO:0019899
GO:0022857
GO:0030154
GO:0030641
GO:0031410
GO:0032991
GO:0033116
GO:0033180
GO:0033181
GO:0033572
GO:0034220
GO:0036295
GO:0042592
GO:0043167
GO:0043226
GO:0045669
GO:0045780
GO:0045851
GO:0045921
GO:0046933
GO:0046961
GO:0048856
GO:0051656
GO:0055085
GO:0070062
GO:0070374
GO:1902600
GO:2001206
ILMN_1697694
TC0X000771.hg
TC0X001937.hg
g4557340_3p_s_at
Participant Of
input
ATP6AP1 binds V-ATPase
hasComponent
V-ATPase:ATP6AP1 [endosome membrane]
Inferred To
Ghost homologue of ATP6AP1 [endosome membrane] (Gallus gallus)
Ghost homologue of ATP6AP1 [endosome membrane] (Plasmodium falciparum)
Ghost homologue of ATP6AP1 [endosome membrane] (Saccharomyces cerevisiae)
Ghost homologue of ATP6AP1 [endosome membrane] (Schizosaccharomyces pombe)
VhaAC45 [endosome membrane] (Drosophila melanogaster)
atp6ap1.2 [endosome membrane] (Xenopus tropicalis)
vha-19 [endosome membrane] (Caenorhabditis elegans)
ATP6AP1 [endosome membrane] (Canis familiaris)
ATP6AP1 [endosome membrane] (Dictyostelium discoideum)
ATP6AP1 [endosome membrane] (Sus scrofa)
atp6ap1a [endosome membrane] (Danio rerio)
Atp6ap1 [endosome membrane] (Mus musculus)
Atp6ap1 [endosome membrane] (Rattus norvegicus)
Cross References
RefSeq
XP_011529481.1
,
NP_001174.2
OpenTargets
ENSG00000071553
ZINC - Substances
VAS1_HUMAN
ZINC - Biogenic
VAS1_HUMAN
ZINC target
Q15904
PRO
Q15904
Target Pathogen
5b354852be737e166372ee4d
HPA
ENSG00000071553-ATP6AP1
GeneCards
Q15904
Ensembl
ENST00000369762
,
ENSG00000071553
,
ENSP00000358777
Orphanet
27598
ZINC - Predictions - Purchasable
VAS1_HUMAN
HMDB Protein
HMDBP09536
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449624 REP
0.643
3
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:O75787 ATP6AP2
3
ATP6AP2 [ficolin-1-rich granule membrane]
(R-HSA-6800921)
ATP6AP2 [tertiary granule membrane]
(R-HSA-6799717)
ATP6AP2 [plasma membrane]
(R-HSA-2022356)
0.527
2
UniProt:P27824 CANX
2
CANX [integral component of lumenal side of endoplasmic reticulum membrane]
(R-HSA-983091)
CANX [endoplasmic reticulum lumen]
(R-HSA-195906)
0.462
3
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