Reactome | ATP6AP1 [endoplasmic reticulum membrane]

ATP6AP1 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-9714332

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

V-type proton ATPase subunit S1, VAS1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15904 ATP6AP1

Gene Names

ATP6AP1, ATP6IP1, ATP6S1, VATPS1, XAP3

Chain

signal peptide:1-41, chain:42-470

Reference Genes

BioGPS Gene:537 ATP6AP1

COSMIC (genes):ATP6AP1 ATP6AP1

CTD Gene:537 ATP6AP1

dbSNP Gene:537 ATP6AP1

ENSEMBL:ENSG00000071553 ATP6AP1

HGNC:868 ATP6AP1

KEGG Gene (Homo sapiens):537 ATP6AP1

Monarch:537 ATP6AP1

NCBI Gene:537 ATP6AP1

OMIM:300197 ATP6AP1

UCSC:Q15904 ATP6AP1

Reference Transcript

Other Identifiers

0005890504

11749258_a_at

11754958_s_at

17108354

207809_s_at

35770_at

3996382

3996383

3996384

3996385

3996386

3996388

3996390

3996391

3996392

3996393

3996394

3996395

3996396

3996397

3996398

3996399

3996400

3996401

3996402

3996403

3996405

537

8170882

A_23_P250462

D16469_at

GE79783

GO:0000166

GO:0002376

GO:0003674

GO:0005515

GO:0005524

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005737

GO:0005768

GO:0005783

GO:0005789

GO:0005886

GO:0006464

GO:0006810

GO:0006811

GO:0006879

GO:0007165

GO:0008150

GO:0008286

GO:0010008

GO:0015031

GO:0016020

GO:0016021

GO:0016192

GO:0016469

GO:0019899

GO:0030154

GO:0030641

GO:0031267

GO:0031410

GO:0032991

GO:0033116

GO:0033180

GO:0033181

GO:0033572

GO:0034220

GO:0036295

GO:0042592

GO:0043167

GO:0043226

GO:0045669

GO:0045780

GO:0045851

GO:0045921

GO:0048856

GO:0051656

GO:0055085

GO:0070062

GO:0070374

GO:1902600

GO:2001206

HMNXSV003029783

ILMN_1697694

TC0X000771.hg

TC0X001937.hg

g4557340_3p_s_at

Participates

as a candidate of

RHOA endoplasmic reticulum effectors [endoplasmic reticulum membrane] (Homo sapiens)

Other forms of this molecule

ATP6AP1 [endosome membrane]

Inferred To

atp6ap1a [endoplasmic reticulum membrane] (Danio rerio)

ATP6AP1 [endoplasmic reticulum membrane] (Canis familiaris)

ATP6AP1 [endoplasmic reticulum membrane] (Sus scrofa)

Atp6ap1 [endoplasmic reticulum membrane] (Mus musculus)

Atp6ap1 [endoplasmic reticulum membrane] (Rattus norvegicus)

Cross References

RefSeq

XP_011529481.1, NP_001174.2

OpenTargets

ENSG00000071553

ZINC - Substances

VAS1_HUMAN

ZINC target

Q15904

ZINC - Biogenic

VAS1_HUMAN

PRO

Q15904

GlyGen

Q15904

PDB

6WLW, 6WM4, 6WM3, 6WM2

GeneCards

Q15904

HPA

ENSG00000071553-ATP6AP1

Ensembl

ENSG00000071553, ENST00000369762, ENSP00000358777

Pharos - Targets

Q15904

ZINC - Predictions - Purchasable

VAS1_HUMAN

Orphanet

27598

HMDB Protein

HMDBP09536

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTD1-PRO_0000449624 REP			0.725	4
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:O75787 ATP6AP2	3	ATP6AP2 [ficolin-1-rich granule membrane] (R-HSA-6800921) ATP6AP2 [tertiary granule membrane] (R-HSA-6799717) ATP6AP2 [plasma membrane] (R-HSA-2022356)	0.527	2