Reactome | TCIRG1 [endosome membrane]

TCIRG1 [endosome membrane]

Stable Identifier

R-HSA-912587

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endosome membrane

Locations in the PathwayBrowser

Expand all

Signal Transduction (Homo sapiens)

- Signaling by Receptor Tyrosine Kinases (Homo sapiens)
  - Signaling by Insulin receptor (Homo sapiens)
    - Insulin receptor recycling (Homo sapiens)
      - ATP6AP1 binds V-ATPase (Homo sapiens)
        
        V-ATPase [endosome membrane] (Homo sapiens)
        
        ATP6V0 [endosome membrane] (Homo sapiens)
        
        ATP6V0A [endosome membrane] (Homo sapiens)
        
        TCIRG1 [endosome membrane] (Homo sapiens)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
        
        V-ATPase [endosome membrane] (Homo sapiens)
        
        ATP6V0 [endosome membrane] (Homo sapiens)
        
        ATP6V0A [endosome membrane] (Homo sapiens)
        
        TCIRG1 [endosome membrane] (Homo sapiens)
      - Endosome acidification (Homo sapiens)
        
        V-ATPase:ATP6AP1 [endosome membrane] (Homo sapiens)
        
        V-ATPase [endosome membrane] (Homo sapiens)
        
        ATP6V0 [endosome membrane] (Homo sapiens)
        
        ATP6V0A [endosome membrane] (Homo sapiens)
        
        TCIRG1 [endosome membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q13488 TCIRG1

Gene Names

TCIRG1, ATP6N1C, ATP6V0A3

Chain

chain:1-830

Reference Genes

BioGPS Gene:10312 TCIRG1

COSMIC (genes):TCIRG1 TCIRG1

CTD Gene:10312 TCIRG1

dbSNP Gene:10312 TCIRG1

ENSEMBL:ENSG00000110719 TCIRG1

HGNC:11647 TCIRG1

KEGG:hsa:10312 TCIRG1

Monarch:10312 TCIRG1

NCBI Gene:10312 TCIRG1

OMIM:604592 TCIRG1

UCSC:Q13488 TCIRG1

Reference Transcript

Other Identifiers

10312

11744180_a_at

11754762_x_at

16728017

204158_PM_s_at

204158_s_at

3337391

3337392

3337393

3337395

3337396

3337397

3337398

3337399

3337400

3337401

3337402

3337403

3337404

3337405

3337406

3337407

3337408

3337409

3337410

3337411

3337412

3337413

3337414

3337415

3337416

3337417

3337418

3337419

3337420

3337421

3337422

3337423

3337424

3337425

3337426

3337427

3337428

3337429

3337430

3337431

3337432

3337433

3337434

3337435

3337436

36028_at

7941985

A_23_P75369

A_33_P3219965

GE59179

GO:0000045

GO:0000220

GO:0001503

GO:0002158

GO:0002376

GO:0005215

GO:0005515

GO:0005634

GO:0005764

GO:0005765

GO:0005768

GO:0005770

GO:0005773

GO:0005886

GO:0006874

GO:0006914

GO:0006915

GO:0006954

GO:0006968

GO:0007035

GO:0007039

GO:0007042

GO:0007163

GO:0008284

GO:0010008

GO:0010155

GO:0010272

GO:0010467

GO:0010468

GO:0012501

GO:0016020

GO:0016064

GO:0016236

GO:0016324

GO:0016471

GO:0021554

GO:0030010

GO:0030099

GO:0030154

GO:0030163

GO:0030183

GO:0030217

GO:0030316

GO:0030667

GO:0030670

GO:0031410

GO:0031529

GO:0033176

GO:0033179

GO:0033365

GO:0035709

GO:0035711

GO:0042476

GO:0043029

GO:0043226

GO:0044691

GO:0045335

GO:0045453

GO:0045667

GO:0045851

GO:0046961

GO:0048856

GO:0048872

GO:0050796

GO:0051117

GO:0051452

GO:0051650

GO:0055085

GO:0060041

GO:0061484

GO:0070166

GO:0071345

GO:0090383

GO:0097188

GO:0101003

GO:0140657

GO:1902600

HMNXSV003024316

HMNXSV003038154

HMNXSV003040372

ILMN_1694486

ILMN_1711994

ILMN_1714859

PH_hs_0003291

TC11000704.hg

TC11002743.hg

TC11002744.hg

TC11002745.hg

U45285_at

g5174620_3p_a_at

Participates

as a member of

ATP6V0A [endosome membrane] (Homo sapiens)

Other forms of this molecule

TCIRG1 [lysosomal membrane]

TCIRG1 [plasma membrane]

TCIRG1 [ficolin-1-rich granule membrane]

TCIRG1 [phagocytic vesicle membrane]

Inferred To

Tcirg1 [endosome membrane] (Mus musculus)

Tcirg1 [endosome membrane] (Rattus norvegicus)

unc-32 [endosome membrane] (Caenorhabditis elegans)

Vha100-3 [endosome membrane] (Drosophila melanogaster)

TCIRG1 [endosome membrane] (Bos taurus)

TCIRG1 [endosome membrane] (Canis familiaris)

TCIRG1 [endosome membrane] (Gallus gallus)

TCIRG1 [endosome membrane] (Plasmodium falciparum)

TCIRG1 [endosome membrane] (Sus scrofa)

tcirg1b [endosome membrane] (Danio rerio)

Vha100-2 [endosome membrane] (Drosophila melanogaster)

vatM [endosome membrane] (Dictyostelium discoideum)

Vha100-1 [endosome membrane] (Drosophila melanogaster)

Vha100-5 [endosome membrane] (Drosophila melanogaster)

STV1 [endosome membrane] (Saccharomyces cerevisiae)

tcirg1 [endosome membrane] (Xenopus tropicalis)

vha-7 [endosome membrane] (Caenorhabditis elegans)

Homologues of TCIRG1 [endosome membrane] (Caenorhabditis elegans)

Homologues of TCIRG1 [endosome membrane] (Drosophila melanogaster)

Homologues of TCIRG1 [endosome membrane] (Saccharomyces cerevisiae)

vph1 [endosome membrane] (Schizosaccharomyces pombe)

Vha100-4 [endosome membrane] (Drosophila melanogaster)

vha-5 [endosome membrane] (Caenorhabditis elegans)

VPH1 [endosome membrane] (Saccharomyces cerevisiae)

vha-6 [endosome membrane] (Caenorhabditis elegans)

Cross References

RefSeq

NP_006044.1, XP_005273766.1, NP_006010.2, XP_011543028.1

Guide to Pharmacology - Targets

825

ENSEMBL

ENST00000265686, ENSP00000265686, ENSP00000434407, ENST00000532635, ENSG00000110719

OpenTargets

ENSG00000110719

GeneCards

TCIRG1

HPA

ENSG00000110719-TCIRG1

PRO

Q13488

Pharos - Targets

Q13488

GlyGen

Q13488

Orphanet

TCIRG1

HMDB Protein

HMDBP09531