Reactome | ATP6V0A1 [phagocytic vesicle membrane]

ATP6V0A1 [phagocytic vesicle membrane]

Stable Identifier

R-HSA-1222308

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

phagocytic vesicle membrane

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q93050 ATP6V0A1

Gene Names

ATP6V0A1, ATP6N1, ATP6N1A, VPP1

Chain

chain:1-837

Reference Genes

BioGPS Gene:535 ATP6V0A1

COSMIC (genes):ATP6V0A1 ATP6V0A1

CTD Gene:535 ATP6V0A1

dbSNP Gene:535 ATP6V0A1

ENSEMBL:ENSG00000033627 ATP6V0A1

HGNC:865 ATP6V0A1

KEGG:hsa:535 ATP6V0A1

Monarch:535 ATP6V0A1

NCBI Gene:535 ATP6V0A1

OMIM:192130 ATP6V0A1

UCSC:Q93050 ATP6V0A1

Reference Transcript

Other Identifiers

11718031_a_at

11718032_a_at

16834302

205095_PM_s_at

205095_s_at

212383_PM_at

212383_at

3721719

3721721

3721722

3721723

3721724

3721725

3721726

3721727

3721731

3721732

3721733

3721734

3721735

3721736

3721739

3721740

3721742

3721743

3721744

3721745

3721746

3721751

3721752

3721753

3721757

3721762

3721763

3721768

3721769

3721770

3721771

3721773

3721774

3721775

3721776

3721777

3721778

3721779

3721781

3721783

39326_at

535

8007228

A_14_P120645

A_24_P333733

GE61236

GO:0000220

GO:0005215

GO:0005515

GO:0005737

GO:0005765

GO:0005794

GO:0005829

GO:0005886

GO:0007035

GO:0007042

GO:0010008

GO:0016020

GO:0016241

GO:0016471

GO:0016607

GO:0030665

GO:0030667

GO:0030670

GO:0030672

GO:0031410

GO:0033176

GO:0033179

GO:0042470

GO:0043226

GO:0043231

GO:0045202

GO:0046961

GO:0048388

GO:0048471

GO:0051117

GO:0055085

GO:0070062

GO:0097401

GO:0101003

GO:0140657

GO:1902600

HMNXSV003022703

HMNXSV003025619

Hs.267871.1.S1_3p_at

ILMN_1752579

PH_hs_0013718

TC17000525.hg

Z71460_at

g4885084_3p_a_at

Participates

as a component of

ATP6V0A [phagocytic vesicle membrane] (Homo sapiens)

Other forms of this molecule

ATP6V0A1 [secretory granule membrane]

ATP6V0A1 [plasma membrane]

ATP6V0A1 [ficolin-1-rich granule membrane]

ATP6V0A1 [endosome membrane]

Inferred To

VPH1 [phagocytic vesicle membrane] (Saccharomyces cerevisiae)

atp6v0a1 [phagocytic vesicle membrane] (Xenopus tropicalis)

Atp6v0a1 [phagocytic vesicle membrane] (Mus musculus)

Atp6v0a1 [phagocytic vesicle membrane] (Rattus norvegicus)

Ghost homologue of ATP6V0A1 [phagocytic vesicle membrane] (Danio rerio)

ATP6V0A1 [phagocytic vesicle membrane] (Bos taurus)

ATP6V0A1 [phagocytic vesicle membrane] (Canis familiaris)

ATP6V0A1 [phagocytic vesicle membrane] (Gallus gallus)

ATP6V0A1 [phagocytic vesicle membrane] (Plasmodium falciparum)

ATP6V0A1 [phagocytic vesicle membrane] (Sus scrofa)

vatM [phagocytic vesicle membrane] (Dictyostelium discoideum)

Vha100-1 [phagocytic vesicle membrane] (Drosophila melanogaster)

unc-32 [phagocytic vesicle membrane] (Caenorhabditis elegans)

vph1 [phagocytic vesicle membrane] (Schizosaccharomyces pombe)

Cross References

RefSeq

NP_001123493.1, NP_001123492.1, NP_005168.2

Guide to Pharmacology - Targets

823

ENSEMBL

ENSP00000264649, ENSP00000515539, ENST00000393829, ENST00000343619, ENSP00000342951, ENST00000703901, ENSP00000377415, ENST00000264649

OpenTargets

ENSG00000033627

HPA

ENSG00000033627-ATP6V0A1

PRO

Q93050

Pharos - Targets

Q93050

GlyGen

Q93050

PDB

6WM4, 6WM3, 6WM2, 7U4T, 6WLW

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38606 ATP6V1A	1	ATP6V1A [cytosol] (R-HSA-912602)	0.527	3
UniProt:P27449 ATP6V0C	7	ATP6V0C [endosome membrane] (R-HSA-912591) ATP6V0C [phagocytic vesicle membrane] (R-HSA-1222603) ATP6V0C [ficolin-1-rich granule membrane] (R-HSA-6800908) ATP6V0C [plasma membrane] (R-HSA-6806254) ATP6V0C [azurophil granule membrane] (R-HSA-6799363) ATP6V0C [tertiary granule membrane] (R-HSA-6800991) ATP6V0C [lysosomal membrane] (R-HSA-9640194)	0.527	3
UniProt:Q15904 ATP6AP1	2	ATP6AP1 [endoplasmic reticulum membrane] (R-HSA-9714332) ATP6AP1 [endosome membrane] (R-HSA-5215981)	0.527	2

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