Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
ATP6AP2 [tertiary granule membrane]
Stable Identifier
R-HSA-6799717
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
tertiary granule membrane
Synonyms
Prorenin receptor, Renin receptor, RENR_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of tertiary granule membrane proteins (Homo sapiens)
Tertiary granule membrane proteins [tertiary granule membrane] (Homo sapiens)
ATP6AP2 [tertiary granule membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:O75787 ATP6AP2
Gene Names
ATP6AP2, ATP6IP2, CAPER, ELDF10, HT028, MSTP009, PSEC0072
Chain
signal peptide:1-16, chain:17-350, chain:17-275, chain:278-350
Reference Genes
BioGPS Gene:10159 ATP6AP2
COSMIC (genes):ATP6AP2 ATP6AP2
CTD Gene:10159 ATP6AP2
dbSNP Gene:10159 ATP6AP2
ENSEMBL:ENSG00000182220 ATP6AP2
ENSEMBL:ENSG00000182220.15 ATP6AP2
HGNC:18305 ATP6AP2
KEGG Gene (Homo sapiens):10159 ATP6AP2
Monarch:10159 ATP6AP2
NCBI Gene:10159 ATP6AP2
OMIM:300556 ATP6AP2
UCSC:O75787 ATP6AP2
Reference Transcript
RefSeq:NM_005765.2 ATP6AP2
Other Identifiers
10159
11715643_a_at
11715644_s_at
11747378_a_at
11747379_x_at
11750028_a_at
17102668
201443_PM_s_at
201443_s_at
201444_PM_s_at
201444_s_at
2373559
3974557
3974558
3974559
3974560
3974561
3974565
3974566
3974567
3974569
3974570
3974573
3974574
3974575
3974576
40903_at
8166805
A_23_P11353
GE80135
GO:0000220
GO:0000421
GO:0002003
GO:0003013
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005764
GO:0005765
GO:0005768
GO:0005773
GO:0005783
GO:0005789
GO:0005886
GO:0007035
GO:0007040
GO:0007042
GO:0009897
GO:0010008
GO:0016020
GO:0016192
GO:0016471
GO:0021626
GO:0021903
GO:0023052
GO:0030177
GO:0030424
GO:0030665
GO:0030672
GO:0031410
GO:0032591
GO:0032914
GO:0033176
GO:0038023
GO:0042995
GO:0043226
GO:0043231
GO:0043408
GO:0045202
GO:0045211
GO:0048069
GO:0048388
GO:0048856
GO:0050886
GO:0051452
GO:0051604
GO:0055085
GO:0060089
GO:0060323
GO:0061795
GO:0070062
GO:0070821
GO:0090263
GO:0097401
GO:0098588
GO:0101003
GO:1902600
HMNXSV003058180
ILMN_1677440
ILMN_1849199
PH_hs_0010821
TC0X000190.hg
g12005668_3p_at
g5031590_3p_a_at
Participates
as a member of
Tertiary granule membrane proteins [tertiary granule membrane] (Homo sapiens)
Other forms of this molecule
ATP6AP2 [ficolin-1-rich granule membrane]
ATP6AP2 [plasma membrane]
Inferred To
atp6ap2 [tertiary granule membrane]
(Xenopus tropicalis)
vha-20 [tertiary granule membrane]
(Caenorhabditis elegans)
ATP6AP2 [tertiary granule membrane]
(Bos taurus)
ATP6AP2 [tertiary granule membrane]
(Canis familiaris)
ATP6AP2 [tertiary granule membrane]
(Dictyostelium discoideum)
ATP6AP2 [tertiary granule membrane]
(Drosophila melanogaster)
ATP6AP2 [tertiary granule membrane]
(Gallus gallus)
ATP6AP2 [tertiary granule membrane]
(Sus scrofa)
wu:fj36c03 [tertiary granule membrane]
(Danio rerio)
Atp6ap2 [tertiary granule membrane]
(Mus musculus)
Atp6ap2 [tertiary granule membrane]
(Rattus norvegicus)
Cross References
RefSeq
NP_005756.2
OpenTargets
ENSG00000182220
GeneCards
O75787
HPA
ENSG00000182220-ATP6AP2
Ensembl
ENST00000636580
,
ENST00000636409
,
ENSP00000490083
,
ENSG00000182220
,
ENSP00000489819
PRO
O75787
Pharos - Targets
O75787
Orphanet
15326
HMDB Protein
HMDBP12594
PDB
3LBS
,
6WM3
,
6WM2
,
3LC8
,
6WLW
,
6WM4
,
7U4T
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P21854 CD72
1
CD72 [plasma membrane]
(R-HSA-198121)
0.556
3
UniProt:Q9NPL8 TIMMDC1
1
TIMMDC1 [mitochondrial inner membrane]
(R-HSA-5689720)
0.556
3
UniProt:Q01453 PMP22
1
PMP22 [plasma membrane]
(R-HSA-9615623)
0.556
3
UniProt:P61421 ATP6V0D1
3
ATP6V0D1 [lysosomal membrane]
(R-HSA-9640177)
ATP6V0D1 [phagocytic vesicle membrane]
(R-HSA-1222571)
ATP6V0D1 [endosome membrane]
(R-HSA-912592)
0.527
2
UniProt:Q15904 ATP6AP1
2
ATP6AP1 [endoplasmic reticulum membrane]
(R-HSA-9714332)
ATP6AP1 [endosome membrane]
(R-HSA-5215981)
0.527
2
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text