BTK [cytosol]

Stable Identifier
R-HSA-197948
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tyrosine-protein kinase BTK, BTK_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q06187 BTK
Gene Names
BTK, AGMX1, ATK, BPK
Chain
initiator methionine:1, chain:2-659
Reference Genes
BioGPS Gene:695 BTK
COSMIC (genes):BTK BTK
CTD Gene:695 BTK
dbSNP Gene:695 BTK
ENSEMBL:ENSG00000010671.18 BTK
HGNC:1133 BTK
KEGG Gene (Homo sapiens):695 BTK
Monarch:695 BTK
NCBI Gene:695 BTK
OMIM:300300 BTK
UCSC:Q06187 BTK
Reference Transcript
Other Identifiers
11730847_a_at
11756709_x_at
17112735
205504_PM_at
205504_at
38213_at
4015705
4015710
4015711
4015713
4015714
4015716
4015718
4015720
4015721
4015724
4015729
4015730
4015731
4015732
4015733
4015734
4015735
4015736
4015738
4015741
4015743
4015745
4015746
4015751
4015752
4015755
695
8174051
A_33_P3277514
GO:0000166
GO:0001780
GO:0001805
GO:0001812
GO:0001818
GO:0002250
GO:0002344
GO:0002376
GO:0002553
GO:0002639
GO:0002721
GO:0002755
GO:0002902
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005515
GO:0005524
GO:0005547
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006351
GO:0006355
GO:0006468
GO:0006915
GO:0006954
GO:0007249
GO:0007498
GO:0008289
GO:0010033
GO:0012501
GO:0016004
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018108
GO:0019722
GO:0023052
GO:0030154
GO:0030163
GO:0030167
GO:0030889
GO:0030890
GO:0031410
GO:0032496
GO:0032693
GO:0032755
GO:0032760
GO:0034614
GO:0035556
GO:0036211
GO:0038083
GO:0038095
GO:0042113
GO:0042802
GO:0043226
GO:0043274
GO:0045087
GO:0045121
GO:0045579
GO:0046777
GO:0046872
GO:0048469
GO:0048471
GO:0048856
GO:0050729
GO:0050766
GO:0050853
GO:0050869
GO:0051092
GO:0061516
GO:0065003
GO:0070664
GO:0071226
GO:0097190
GO:0098542
GO:0098761
GO:0098772
GO:0140096
GO:0150153
GO:1900227
GO:1901135
GO:1901647
GO:1990959
HMNXSV003005100
ILMN_1662026
PH_hs_0009711
TC0X001218.hg
TC0X002155.hg
U78027_rna4_at
g4557376_3p_at
Participates
as a component of
as an input of
as a member of
as a candidate of
Other forms of this molecule
Active BTK [cytosol]
p-Y223,Y551-BTK [cytosol]
p-Y551-BTK [cytosol]
p-Y551-BTK [plasma membrane]
p-Y223,Y551-BTK [plasma membrane]
Inferred To
Btk [cytosol] (Mus musculus)
BTK [cytosol] (Bos taurus)
BTK [cytosol] (Canis familiaris)
BTK [cytosol] (Danio rerio)
BTK [cytosol] (Drosophila melanogaster)
BTK [cytosol] (Gallus gallus)
BTK [cytosol] (Rattus norvegicus)
BTK [cytosol] (Sus scrofa)
BTK [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
ZINC - World Drugs
Guide to Pharmacology - Targets
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
PDB
ZINC - Investigational
GeneCards
HPA
Ensembl
Pharos - Targets
Orphanet
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (17)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P78347 GTF2I      0.724 6
 UniProt:Q8WV28 BLNK  2 0.667 4
 IntAct:EBI-1521221      0.633 4
 UniProt:Q06187 BTK  6 0.623 3
 UniProt:Q99856 ARID3A  1 0.558 3
 UniProt:Q13444 ADAM15  1 0.558 2
 UniProt:P21145 MAL      0.556 5
 UniProt:P50222 MEOX2      0.556 3
 UniProt:P62993 GRB2  1 0.547 2
 UniProt:Q6NXT1 ANR54      0.527 2
 UniProt:O60239 3BP5      0.524 4
 UniProt:Q04759 PRKCQ  9 0.524 2
 UniProt:P08238 HSP90AB1  6 0.524 2
 ChEBI:39112 BOSUTINIB      0.499 2
 ChEBI:49375 DASATINIB      0.499 2
 UniProt:Q92569 PIK3R3  2 0.488 2
 UniProt:Q9P2D0 IBTK      0.463 2
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