BTK [cytosol]

Stable Identifier
R-HSA-197948
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Tyrosine-protein kinase BTK, BTK_HUMAN
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:Q06187 BTK
Gene Names
BTK, AGMX1, ATK, BPK
Chain
initiator methionine:, chain:2-659
Reference Genes
BioGPS Gene:695 BTK
COSMIC (genes):BTK BTK
CTD Gene:695 BTK
dbSNP Gene:695 BTK
ENSEMBL:ENSG00000010671 BTK
HGNC:1133 BTK
KEGG:hsa:695 BTK
Monarch:695 BTK
NCBI Gene:695 BTK
OMIM:300300 BTK
UCSC:Q06187 BTK
Reference Transcript
Other Identifiers
11730847_a_at
11735122_at
11756709_x_at
17112729
17112735
205504_PM_at
205504_at
38213_at
4015701
4015702
4015703
4015704
4015705
4015710
4015711
4015712
4015713
4015714
4015715
4015716
4015717
4015718
4015719
4015720
4015721
4015722
4015723
4015724
4015728
4015729
4015730
4015731
4015732
4015733
4015734
4015735
4015736
4015738
4015739
4015741
4015743
4015744
4015745
4015746
4015747
4015751
4015752
4015753
4015754
4015755
695
71820_at
8174047
8174051
ADDON002881.hg
A_23_P137139
A_23_P358417
A_33_P3277514
GE61511
GE63153
GO:0001780
GO:0001805
GO:0001812
GO:0001818
GO:0002250
GO:0002344
GO:0002376
GO:0002553
GO:0002639
GO:0002721
GO:0002755
GO:0002902
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005515
GO:0005524
GO:0005547
GO:0005634
GO:0005737
GO:0005829
GO:0005886
GO:0006355
GO:0006468
GO:0006915
GO:0007498
GO:0008289
GO:0012501
GO:0016004
GO:0016301
GO:0016740
GO:0018108
GO:0019722
GO:0030163
GO:0030167
GO:0030889
GO:0030890
GO:0031410
GO:0032496
GO:0032693
GO:0032755
GO:0032760
GO:0034614
GO:0035556
GO:0038095
GO:0042113
GO:0042802
GO:0043226
GO:0043274
GO:0045087
GO:0045121
GO:0045579
GO:0046872
GO:0048469
GO:0048471
GO:0048856
GO:0050766
GO:0050852
GO:0050853
GO:0050869
GO:0051092
GO:0061516
GO:0070664
GO:0071226
GO:0097190
GO:0098542
GO:0098761
GO:0098772
GO:0140096
GO:0150153
GO:1900227
GO:1901135
GO:1901647
GO:1990959
HMNXSV003005100
HMNXSV003032904
ILMN_1662026
PH_hs_0009711
TC0X001217.hg
TC0X001218.hg
TC0X002155.hg
U78027_rna4_at
g4557376_3p_at
Participates
as a component of
as an input of
as a member of
as a candidate of
Other forms of this molecule
p-Y223,Y551-BTK [plasma membrane]
p-Y551-BTK [plasma membrane]
p-Y551-BTK [cytosol]
p-Y223,Y551-BTK [cytosol]
Active BTK [cytosol]
Inferred To
Btk [cytosol] (Mus musculus)
BTK [cytosol] (Bos taurus)
BTK [cytosol] (Canis familiaris)
BTK [cytosol] (Drosophila melanogaster)
BTK [cytosol] (Gallus gallus)
BTK [cytosol] (Rattus norvegicus)
BTK [cytosol] (Sus scrofa)
BTK [cytosol] (Xenopus tropicalis)
Cross References
RefSeq
Guide to Pharmacology - Targets
ENSEMBL
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC - Biogenic
ZINC target
PRO
GlyGen
PDB
ZINC - Investigational
GeneCards
BTK
HPA
Pharos - Targets
Orphanet
BTK
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (20)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P78347 GTF2I      0.724 6
 UniProt:Q8WV28 BLNK  2 0.667 4
 UniProt:Q6NXT1 ANR54      0.643 4
 UniProt:P08238 HSP90AB1  6 0.641 3
 IntAct:EBI-1521221      0.633 4
 UniProt:Q06187 BTK  6 0.623 3
 UniProt:Q9BVA0 KTNB1      0.589 2
 UniProt:Q13444 ADAM15  1 0.558 2
 UniProt:Q99856 ARID3A  1 0.558 3
 UniProt:P50222 MEOX2      0.556 3
 UniProt:P21145 MAL      0.556 5
 UniProt:P62993 GRB2  1 0.547 2
 UniProt:Q16543 CDC37  1 0.527 3
 UniProt:Q8N5M4 TTC9C      0.527 2
 UniProt:Q04759 PRKCQ  9 0.524 2
 UniProt:O60239 3BP5      0.524 4
 ChEBI:49375 DASATINIB      0.499 2
 ChEBI:39112 BOSUTINIB      0.499 2
 UniProt:Q92569 PIK3R3  2 0.488 2
 UniProt:Q9P2D0 IBTK      0.463 2
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