PRKCQ(355-706) [cytosol]

Stable Identifier
R-HSA-212514
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Protein kinase C, theta type fragment (355-706), nPKC-theta
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
9252332 Caspase-3-mediated cleavage of protein kinase C theta in induction of apoptosis

Datta, R, Kojima, H, Yoshida, K, Kufe, D

J Biol Chem 1997
9431985 The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis

Mizuno, K, Noda, K, Araki, T, Imaoka, T, Kobayashi, Y, Akita, Y, Shimonaka, M, Kishi, S, Ohno, S

Eur J Biochem 1997
External Reference Information
External Reference
UniProt:Q04759 PRKCQ
Gene Names
PRKCQ, PRKCT
Chain
chain:1-706
Reference Genes
BioGPS Gene:5588 PRKCQ
COSMIC (genes):PRKCQ PRKCQ
CTD Gene:5588 PRKCQ
dbSNP Gene:5588 PRKCQ
ENSEMBL:ENSG00000065675 PRKCQ
HGNC:9410 PRKCQ
KEGG Gene (Homo sapiens):5588 PRKCQ
Monarch:5588 PRKCQ
NCBI Gene:5588 PRKCQ
OMIM:600448 PRKCQ
UCSC:Q04759 PRKCQ
Reference Transcript
Other Identifiers
0002940053
04070+2.7.11.13
11728077_s_at
11747467_a_at
11750753_a_at
16711533
1XJD
2081_s_at
210038_at
210039_s_at
2ENJ
2ENN
2ENZ
2JED
3275955
3275956
3275957
3275958
3275959
3275960
3275963
3275967
3275969
3275971
3275972
3275977
3275978
3275979
3275981
3275987
3275989
3275990
3275991
3275995
3275997
3276002
3276010
3276011
38949_at
4Q9Z
4RA5
5588
5F9E
65279
73098
7931930
A0A087X0I9
A_23_P1374
AAA60101
AAA75571
AAI01466
AAI13360
AAU29340
AK293935
AL137145
AL158043
AY702977
BAG57313
BC101465
BC113359
CCDS55701
CCDS60482
CCDS7079
ENSG00000065675
ENSP00000263125
ENSP00000380361
ENSP00000441752
ENST00000263125
ENST00000263125.9
ENST00000397176
ENST00000397176.6
ENST00000539722
ENST00000539722.5
EntrezGene:5588
EntrezGene:PRKCQ
g558098_3p_a_at
GE79759
GE88182
GO:0000166
GO:0000902
GO:0001558
GO:0001772
GO:0002376
GO:0003674
GO:0004672
GO:0004674
GO:0004697
GO:0005515
GO:0005524
GO:0005575
GO:0005622
GO:0005623
GO:0005737
GO:0005815
GO:0005829
GO:0005856
GO:0005886
GO:0006259
GO:0006355
GO:0006464
GO:0006468
GO:0006509
GO:0006950
GO:0006954
GO:0007155
GO:0007165
GO:0007411
GO:0008150
GO:0008219
GO:0008283
GO:0009058
GO:0016020
GO:0016235
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0030154
GO:0030168
GO:0032212
GO:0032740
GO:0032753
GO:0034451
GO:0034641
GO:0035556
GO:0038095
GO:0040007
GO:0040011
GO:0042102
GO:0042592
GO:0043167
GO:0043226
GO:0045086
GO:0045652
GO:0046627
GO:0046872
GO:0048856
GO:0048870
GO:0050852
GO:0050870
GO:0051092
GO:0051276
GO:0051973
GO:0060326
GO:0070233
GO:0090330
GO:1904355
GO:2000318
GO:2000570
HGNC:9410
HPA065279
HPA073098
Hs.211593.0.S2_3p_at
ILMN_1733421
IPR000719
IPR000961
IPR002219
IPR008271
IPR011009
IPR014376
IPR017441
IPR017892
IPR020454
IPR027264
IPR034668
IPR035892
L01087
L01087_at
L07032
MIM:600448
NM_001242413
NM_001282644
NM_001282645
NM_001323265
NM_001323266
NM_001323267
NM_006257
NP_001229342
NP_001269573
NP_001269574
NP_001310194
NP_001310195
NP_001310196
NP_006248
PF00069
PF00130
PF00433
PH_hs_0024719
PH_hs_0033184
PR00008
PRKCQ
PRKCQ-201
PRKCQ-202
PRKCQ-203
SM00109
SM00133
SM00220
TC10001014.hg
UPI000012DF74
UPI00004DC51A
UPI00017A701C
XM_005252496
XM_005252497
XM_024448076
XM_024448077
XP_005252553
XP_005252554
XP_024303844
XP_024303845
Participant Of
output
Other forms of this molecule
PRKCQ [photoreceptor disc membrane]
PRKCQ(1-354) [cytosol]
PRKCQ [cytosol]
p-Y90,T538,S676,S695-PRKCQ [plasma membrane]
PRKQC closed conformation [cytosol]
PRKCQ [plasma membrane]
p-Y90-PRKCQ [plasma membrane]
p-Y90,T219,T538,S676,S695-PRKCQ [plasma membrane]
Inferred To
PKC1 [cytosol] (Saccharomyces cerevisiae)
pck1 [cytosol] (Schizosaccharomyces pombe)
tpa-1 [cytosol] (Caenorhabditis elegans)
PRKCQ [cytosol] (Bos taurus)
PRKCQ [cytosol] (Canis familiaris)
Homologues of PRKCQ(355-706) [cytosol] (Dictyostelium discoideum)
Homologues of PRKCQ(355-706) [cytosol] (Schizosaccharomyces pombe)
PRKCQ(355-706) [cytosol] (Dictyostelium discoideum)
PRKCQ(355-706) [cytosol] (Gallus gallus)
PRKCQ(355-706) [cytosol] (Sus scrofa)
Pkcdelta [cytosol] (Drosophila melanogaster)
pck2 [cytosol] (Schizosaccharomyces pombe)
prkcq [cytosol] (Danio rerio)
prkcq [cytosol] (Xenopus tropicalis)
pkbA [cytosol] (Dictyostelium discoideum)
Prkcq [cytosol] (Mus musculus)
Prkcq [cytosol] (Rattus norvegicus)
Cross References
RefSeq
ZINC - World Drugs
OpenTargets
ZINC - FDA approved
ZINC - Substances
ZINC target
ZINC - Biogenic
PRO
PDB
ZINC - Investigational
ZINC - Metabolites
IntEnz
HPA
GeneCards
Ensembl
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (7)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P06241 FYN  6 0.66 7
 UniProt:Q8IVH8 M4K3      0.639 4
 UniProt:O76003 GLRX3  1 0.602 5
 UniProt:Q05513 PRKCZ  5 0.581 3
 UniProt:Q00613 HSF1  11 0.544 2
 UniProt:Q06187 BTK  6 0.524 2
 UniProt:P06239 LCK  4 0.499 2
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