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Btk [cytosol]
Stable Identifier
R-DME-197948
Type
Protein [EntityWithAccessionedSequence]
Species
Drosophila melanogaster
Compartment
cytosol
Synonyms
BTK, P08630
Locations in the PathwayBrowser
Expand all
Immune System (Drosophila melanogaster)
Innate Immune System (Drosophila melanogaster)
DAP12 interactions (Drosophila melanogaster)
DAP12 signaling (Drosophila melanogaster)
Activation of RAC1 by VAV2/3 (Drosophila melanogaster)
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV [plasma membrane] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (12/13) signalling events (Drosophila melanogaster)
BTK in G alpha (12)-BTK complex is activated (Drosophila melanogaster)
G alpha (12):BTK [plasma membrane] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
G alpha (12) binds BTK (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
G alpha (12):BTK [plasma membrane] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
G alpha (12):BTK [plasma membrane] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
Active Gq binds BTK (Drosophila melanogaster)
Active Gq:BTK [plasma membrane] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
BTK in active Gq-BTK complex is activated (Drosophila melanogaster)
Active Gq:BTK [plasma membrane] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
Gq-BTK complex dissociates to Active BTK and Gq (Drosophila melanogaster)
Active Gq:BTK [plasma membrane] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
Btk [cytosol] (Drosophila melanogaster)
External Reference Information
External Reference
UniProt:P08630
Gene Names
Btk
Reference Genes
BioGPS Gene:34132 Btk
ENSEMBL:FBgn0003502
FlyBase:FBgn0003502
KEGG:dme:Dmel_CG8049 Btk
Monarch:34132 Btk
NCBI Gene:34132 Btk
UCSC:P08630 Btk
Reference Transcript
RefSeq:NM_164804.2 Btk
RefSeq:NM_057397.6 Btk
RefSeq:NM_001103650.2 Btk
RefSeq:NM_001103651.3 Btk
RefSeq:NM_164805.2 Btk
RefSeq:NM_057398.4 Btk
Other Identifiers
142240_at
142241_at
153920_at
1636123_at
1636265_s_at
34132
GO:0000166
GO:0002009
GO:0003824
GO:0004672
GO:0004713
GO:0004715
GO:0005515
GO:0005524
GO:0005737
GO:0005886
GO:0006468
GO:0007254
GO:0007300
GO:0007301
GO:0007349
GO:0007391
GO:0007424
GO:0007435
GO:0007485
GO:0007619
GO:0008258
GO:0008270
GO:0008340
GO:0016301
GO:0016740
GO:0022414
GO:0030036
GO:0030717
GO:0030723
GO:0030833
GO:0035277
GO:0035556
GO:0042023
GO:0045172
GO:0045177
GO:0046872
GO:0046960
GO:0048468
GO:0048477
GO:0048856
GO:0050877
GO:0065008
GO:0071944
GO:0140096
Participates
as an output of
Gq-BTK complex dissociates to Active BTK and Gq (Drosophila melanogaster)
G alpha (12)-BTK complex dissociates to Active BTK and G alpha (12) (Drosophila melanogaster)
as an input of
Active Gq binds BTK (Drosophila melanogaster)
G alpha (12) binds BTK (Drosophila melanogaster)
as a component of
Active Gq:BTK [plasma membrane] (Drosophila melanogaster)
G alpha (12):BTK [plasma membrane] (Drosophila melanogaster)
p-5Y-LAT:PLCG1:GADS:p-3Y-SLP-76:BTK:p-VAV [plasma membrane] (Drosophila melanogaster)
p-5Y-LAT:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG:VAV:BTK:PIP3 [plasma membrane] (Drosophila melanogaster)
p-5Y-LAT:p-SHC1:GRB2:SOS1:GADS:p-Y113,Y128,Y145-SLP-76:PLCG1:VAV:TEC kinases:PIP3 [plasma membrane] (Drosophila melanogaster)
Other forms of this molecule
Btk [cytosol]
phospho-Btk [cytosol]
phospho-Btk [cytosol]
phospho-Btk [cytosol]
phospho-Btk [cytosol]
Btk [cytosol]
Btk [cytosol]
Btk [cytosol]
Btk [cytosol]
Btk [cytosol]
phospho-Btk [cytosol]
phospho-Btk [cytosol]
phospho-Btk [cytosol]
phospho-Btk [cytosol]
Inferred From
Active BTK [cytosol]
(Homo sapiens)
TEC,BTK,ITK,(TXK) [cytosol]
(Homo sapiens)
BTK [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_723369.1
,
NP_723370.1
,
NP_476745.1
,
NP_001097121.1
,
NP_476746.1
,
NP_001097120.1
ENSEMBL
FBgn0003502
,
FBpp0079236
,
FBpp0111749
,
FBtr0112836
,
FBpp0079237
,
FBtr0079616
,
FBtr0079617
IntEnz
2.7.10.2
PRO
P08630
FlyBase
FBgn0003502
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