Reactome | FBXO5 [nucleoplasm]

FBXO5 [nucleoplasm]

Stable Identifier

R-HSA-174060

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Emi1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9UKT4 FBXO5

Gene Names

FBXO5, EMI1, FBX5

Chain

chain:1-447

Reference Genes

BioGPS Gene:26271 FBXO5

COSMIC (genes):FBXO5 FBXO5

CTD Gene:26271 FBXO5

dbSNP Gene:26271 FBXO5

ENSEMBL:ENSG00000112029 FBXO5

HGNC:13584 FBXO5

KEGG Gene (Homo sapiens):26271 FBXO5

Monarch:26271 FBXO5

NCBI Gene:26271 FBXO5

OMIM:606013 FBXO5

UCSC:Q9UKT4 FBXO5

Reference Transcript

Other Identifiers

0003060692

11724963_s_at

17024980

218875_s_at

234863_x_at

26271

2980242

2980243

2980244

2980245

2980246

2980248

2980250

2980251

2980252

2980254

2980255

2980256

2980257

48490_at

8130374

A_23_P8241

A_33_P3384871

GE58468

GO:0000003

GO:0000083

GO:0000278

GO:0001556

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005634

GO:0005654

GO:0005737

GO:0005819

GO:0005829

GO:0005856

GO:0006275

GO:0006464

GO:0006950

GO:0007010

GO:0007049

GO:0007057

GO:0007059

GO:0007088

GO:0007346

GO:0007568

GO:0008150

GO:0008283

GO:0008284

GO:0009056

GO:0009058

GO:0010971

GO:0010997

GO:0016050

GO:0016567

GO:0019899

GO:0019901

GO:0021700

GO:0022607

GO:0030154

GO:0030234

GO:0031145

GO:0032876

GO:0034641

GO:0040011

GO:0040020

GO:0043167

GO:0043226

GO:0045669

GO:0045835

GO:0045841

GO:0046785

GO:0046872

GO:0048856

GO:0048870

GO:0051225

GO:0051276

GO:0051301

GO:0051444

GO:0065003

GO:0070169

GO:0072687

GO:0140014

GO:1901990

GO:1904667

GO:1905322

GO:1990948

GO:2000773

GO:2001021

Hs.272027.1.S1_3p_s_at

ILMN_1710676

ILMN_2121555

PH_hs_0014007

TC06002240.hg

Participant Of

hasComponent

input

output

FBXO5 gene expression is stimulated by E2F1

Other forms of this molecule

p-S145,S149-FBXO5 [nucleoplasm]

p-S182-FBXO5 [nucleoplasm]

p-S145,S149-FBXO5 [cytosol]

p-S182-FBXO5 [cytosol]

p-FBXO5 [nucleoplasm]

Inferred To

Rca1 [nucleoplasm] (Drosophila melanogaster)

Fbxo5 [nucleoplasm] (Mus musculus)

Fbxo5 [nucleoplasm] (Rattus norvegicus)

FBXO5 [nucleoplasm] (Bos taurus)

FBXO5 [nucleoplasm] (Canis familiaris)

FBXO5 [nucleoplasm] (Gallus gallus)

FBXO5 [nucleoplasm] (Sus scrofa)

fbxo5 [nucleoplasm] (Danio rerio)

fbxo5 [nucleoplasm] (Xenopus tropicalis)

Cross References

RefSeq

NP_036309.1, NP_001135994.1

OpenTargets

ENSG00000112029

GeneCards

Q9UKT4

HPA

ENSG00000112029-FBXO5

Ensembl

ENST00000229758, ENSP00000229758, ENSG00000112029, ENST00000367241, ENSP00000356210

PRO

Q9UKT4

PDB

4UI9, 2M6N

Interactors (6)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P63208 SKP1	2	SKP1 [cytosol] (R-HSA-174150) SKP1 [nucleoplasm] (R-HSA-187538)	0.743	5
UniProt:O60447 EVI5			0.645	6
UniProt:P30260 CDC27	2	CDC27 [nucleoplasm] (R-HSA-174175) CDC27 [cytosol] (R-HSA-174073)	0.564	2
UniProt:Q8R349	2	Cdc16 [cytosol] (R-MMU-174156) Cdc16 [nucleoplasm] (R-MMU-174049)	0.564	3
UniProt:Q8BGZ4	2	Cdc23 [cytosol] (R-MMU-174137) Cdc23 [nucleoplasm] (R-MMU-174228)	0.564	3
UniProt:Q99JP4	2	Cdc26 [cytosol] (R-MMU-174052) Cdc26 [nucleoplasm] (R-MMU-174216)	0.564	2

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