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What is Reactome ?
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Release Calendar
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License Agreement
Privacy Notice
Disclaimer
Digital Preservation
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CDC23 [cytosol]
Stable Identifier
R-HSA-174137
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Apc8/Cdc23
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
Mitotic Spindle Checkpoint (Homo sapiens)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
Binding of the MCC complex to the APC/C complex (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Separation of Sister Chromatids (Homo sapiens)
Association of Securin with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated cell cycle proteins (Homo sapiens)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of Cyclin B (Homo sapiens)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Cyclin B (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
APC/C:Cdc20 mediated degradation of Securin (Homo sapiens)
Association of Securin with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Homo sapiens)
APC-Cdc20 mediated degradation of Nek2A (Homo sapiens)
Association of Nek2A with MCC:APC/C (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Nek2A (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Multiubiquitination of Nek2A (Homo sapiens)
Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Homo sapiens)
Association of Cyclin A with the APC/C (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Degradation multiubiquitinated Cyclin A (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)
Association of Cdh1 with the APC/C (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Dissociation of Cdc20 from APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Regulation of APC/C activators between G1/S and early anaphase (Homo sapiens)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
Binding of the MCC complex to the APC/C complex (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
CDC23 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UJX2 CDC23
Gene Names
CDC23, ANAPC8
Chain
initiator methionine:, chain:2-597
Reference Genes
BioGPS Gene:8697 CDC23
COSMIC (genes):CDC23 CDC23
CTD Gene:8697 CDC23
dbSNP Gene:8697 CDC23
ENSEMBL:ENSG00000094880 CDC23
HGNC:1724 CDC23
KEGG:hsa:8697 CDC23
Monarch:8697 CDC23
NCBI Gene:8697 CDC23
OMIM:603462 CDC23
UCSC:Q9UJX2 CDC23
Reference Transcript
RefSeq:NM_004661.3 CDC23
Other Identifiers
11721444_a_at
11752517_a_at
11757838_s_at
11759740_x_at
17000404
202892_PM_at
202892_at
223651_PM_x_at
223651_x_at
2877316
2877317
2877318
2877319
2877320
2877321
2877325
2877326
2877327
2877328
2877329
2877330
2877332
2877333
2877334
2877335
2877336
2877337
2877338
2877339
2877340
2877341
2877342
2877343
2877345
31877_at
3250677
68170_r_at
8114396
8697
A_23_P133629
A_24_P913227
GE54494
GO:0000278
GO:0003824
GO:0004842
GO:0005515
GO:0005654
GO:0005680
GO:0005829
GO:0006511
GO:0007080
GO:0007091
GO:0007096
GO:0007346
GO:0016567
GO:0016740
GO:0030071
GO:0030163
GO:0031145
GO:0045842
GO:0051301
GO:0051445
GO:0070936
GO:0070979
GO:0140096
GO:0141198
HMNXSV003025907
HMNXSV003049724
ILMN_1799688
PH_hs_0009232
TC05001827.hg
g13528932_3p_at
g4757947_3p_at
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
Other forms of this molecule
CDC23 [nucleoplasm]
Inferred To
GFRA3 [cytosol]
(Canis familiaris)
CDC23 [cytosol]
(Bos taurus)
CDC23 [cytosol]
(Gallus gallus)
CDC23 [cytosol]
(Saccharomyces cerevisiae)
CDC23 [cytosol]
(Sus scrofa)
Cdc23 [cytosol]
(Drosophila melanogaster)
Cdc23 [cytosol]
(Mus musculus)
Cdc23 [cytosol]
(Rattus norvegicus)
anapc8 [cytosol]
(Dictyostelium discoideum)
mat-3 [cytosol]
(Caenorhabditis elegans)
cut23 [cytosol]
(Schizosaccharomyces pombe)
cdc23 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_004652.2
OpenTargets
ENSG00000094880
ENSEMBL
ENSP00000378348
,
ENST00000394886
,
ENST00000394884
,
ENSP00000378350
,
ENSG00000094880
HPA
ENSG00000094880-CDC23
GeneCards
CDC23
PRO
Q9UJX2
Pharos - Targets
Q9UJX2
GlyGen
Q9UJX2
PDB
6TM5
,
5A31
,
5LCW
,
6Q6G
,
6Q6H
,
5KHU
,
4UI9
,
5L9T
,
5L9U
,
6TNT
,
8TAU
,
6TLJ
,
8PKP
,
8TAR
,
5G05
,
5G04
,
9GAW
,
5KHR
Interactors (23)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q96CV9 OPTN
6
p-S177,S473,S513-OPTN [cytosol]
(R-HSA-9687840)
OPTN [cytosol]
(R-HSA-9687907)
p-S177-OPTN [cytosol]
(R-HSA-2562525)
p-S177-OPTN [nucleoplasm]
(R-HSA-2562595)
OPTN [Golgi membrane]
(R-HSA-2161111)
OPTN [recycling endosome membrane]
(R-HSA-8854141)
0.795
8
UniProt:O60566 BUB1B
1
BUB1B [cytosol]
(R-HSA-141436)
0.788
5
UniProt:Q8NC69 KCTD6
1
KCTD6 [cytosol]
(R-HSA-8863321)
0.718
6
UniProt:P14373 TRIM27
2
TRIM27 [cytosol]
(R-HSA-8851002)
TRIM27 [nucleoplasm]
(R-HSA-2997690)
0.666
4
UniProt:Q9UM11 FZR1
5
FZR1 [cytosol]
(R-HSA-174249)
FZR1 [nucleoplasm]
(R-HSA-174099)
p-FZR1 [nucleoplasm]
(R-HSA-174257)
p-FZR1 [cytosol]
(R-HSA-174193)
p-S151-FZR1 [nucleoplasm]
(R-HSA-9929805)
0.643
5
UniProt:Q12834 CDC20
3
CDC20 [cytosol]
(R-HSA-141412)
CDC20 [nucleoplasm]
(R-HSA-174112)
PolyUb-CDC20 [nucleoplasm]
(R-HSA-6783069)
0.643
4
UniProt:Q9JJ66
3
Cdc20 [nucleoplasm]
(R-MMU-6783069)
Cdc20 [nucleoplasm]
(R-MMU-174112)
Cdc20 [cytosol]
(R-MMU-141412)
0.564
2
UniProt:P14136 GFAP
3
p-GFAP [lysosomal membrane]
(R-HSA-9626054)
GFAP [lysosomal membrane]
(R-HSA-9625195)
GFAP [cytosol]
(R-HSA-1253311)
0.556
3
UniProt:Q53HV7 SMUG1
1
SMUG1 [nucleoplasm]
(R-HSA-110161)
0.556
3
UniProt:Q9BUH8 BEGAIN
1
BEGAIN [cytosol]
(R-HSA-6794250)
0.556
3
UniProt:Q15742 NAB2
1
NAB2 [nucleoplasm]
(R-HSA-9612177)
0.556
3
UniProt:Q9Y5V3 MAGED1
1
MAGED1 [cytosol]
(R-HSA-196002)
0.556
3
UniProt:P10745 RBP3
1
RBP3 [extracellular region]
(R-HSA-2984190)
0.556
3
UniProt:Q8IUQ4 SIAH1
1
SIAH1 [cytosol]
(R-HSA-374563)
0.556
3
UniProt:P63000 RAC1
6
RAC1 [plasma membrane]
(R-HSA-351141)
RAC1 [cytosol]
(R-HSA-442615)
RAC1 [endoplasmic reticulum membrane]
(R-HSA-5672076)
GGC-PalmC-RAC1 [plasma membrane]
(R-HSA-2316446)
RAC1 [secretory granule membrane]
(R-HSA-6804770)
RAC1 [ficolin-1-rich granule membrane]
(R-HSA-6804802)
0.556
3
UniProt:O14832 PHYH
4
PHYH [peroxisomal matrix]
(R-HSA-389574)
PHYH(1-338) [cytosol]
(R-HSA-9033143)
PHYH(1-338) [peroxisomal matrix]
(R-HSA-9033535)
PHYH(1-30) [peroxisomal matrix]
(R-HSA-9033518)
0.556
3
UniProt:P55212 CASP6
5
CASP6(194-293) [cytosol]
(R-HSA-266128)
CASP6(24-179) [cytosol]
(R-HSA-350313)
CASP6(24-179) [nucleoplasm]
(R-HSA-352247)
CASP6(194-293) [nucleoplasm]
(R-HSA-352246)
CASP6 (1-293) [cytosol]
(R-HSA-6798132)
0.556
3
UniProt:Q13895 BYSL
2
BYSL [nucleoplasm]
(R-HSA-6791526)
BYSL [cytosol]
(R-HSA-6791518)
0.556
5
UniProt:O75791 GRAP2
1
GRAP2 [cytosol]
(R-HSA-202367)
0.527
2
UniProt:O43684 BUB3
1
BUB3 [cytosol]
(R-HSA-141416)
0.527
2
UniProt:Q13257 MAD2L1
2
MAD2L1 [cytosol]
(R-HSA-141400)
Activated MAD2L1 [cytosol]
(R-HSA-141447)
0.527
2
UniProt:Q9UKT4 FBXO5
6
p-S182-FBXO5 [cytosol]
(R-HSA-177324)
p-S145,S149-FBXO5 [cytosol]
(R-HSA-174207)
FBXO5 [nucleoplasm]
(R-HSA-174060)
p-S182-FBXO5 [nucleoplasm]
(R-HSA-176447)
p-S145,S149-FBXO5 [nucleoplasm]
(R-HSA-174220)
p-FBXO5 [nucleoplasm]
(R-HSA-163049)
0.527
2
UniProt:P51955 NEK2
1
NEK2 [cytosol]
(R-HSA-177329)
0.527
2
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