Association of Emi1 with Cdc20

Stable Identifier
R-HSA-174235
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Association of Emi1 with Cdc20
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout

In addition to its association with Cdh1 in G1 phase, Emi1 further contributes the inactivation of the APC/C between G2 and prophase by associating with another APC/C activator, Cdc20.

Literature References
PubMed ID Title Journal Year
14743218 The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

Choi, EJ, Kim, JW, Lim, DS, Lee, H, Choi, N, Kirschner, MW, Kim, H, Song, SJ, Song, MS, Hong, HK, Lee, JH, Chang, JS, Ayad, NG, Kim, J

Nat Cell Biol 2004
11988738 E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

Reimann, JD, Lukas, J, Hsu, JY, Sorensen, CS, Jackson, PK

Nat Cell Biol 2002
Participants
Input
Output
Participates
as an event of
Orthologous Events
Association of Emi1 with Cdc20 (Bos taurus)
Association of Emi1 with Cdc20 (Canis familiaris)
Association of Emi1 with Cdc20 (Danio rerio)
Association of Emi1 with Cdc20 (Drosophila melanogaster)
Association of Emi1 with Cdc20 (Gallus gallus)
Association of Emi1 with Cdc20 (Mus musculus)
Association of Emi1 with Cdc20 (Rattus norvegicus)
Association of Emi1 with Cdc20 (Sus scrofa)
Association of Emi1 with Cdc20 (Xenopus tropicalis)
Authored
Castro, A  (2006-01-26)
Lorca, T  (2006-01-26)
Reviewed
Peters, JM  (2006-03-28)
Created
Matthews, L  (2006-02-17)
Cite Us!