Association of Emi1 with Cdc20

Stable Identifier
R-HSA-174235
Type
Reaction [binding]
Species
Homo sapiens
Compartment
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In addition to its association with Cdh1 in G1 phase, Emi1 further contributes the inactivation of the APC/C between G2 and prophase by associating with another APC/C activator, Cdc20.

Literature References
PubMed ID Title Journal Year
11988738 E2F-dependent accumulation of hEmi1 regulates S phase entry by inhibiting APC(Cdh1)

Hsu, JY, Reimann, JD, Sorensen, CS, Lukas, J, Jackson, PK

Nat Cell Biol 2002
14743218 The tumour suppressor RASSF1A regulates mitosis by inhibiting the APC-Cdc20 complex

Song, MS, Song, SJ, Ayad, NG, Chang, JS, Lee, JH, Hong, HK, Lee, H, Choi, N, Kim, J, Kim, H, Kim, JW, Choi, EJ, Kirschner, MW, Lim, DS

Nat Cell Biol 2004
Participants
Participant Of
Orthologous Events
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Created