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ANAPC5 [cytosol]
Stable Identifier
R-HSA-174211
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Apc5
Locations in the PathwayBrowser
Expand all
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
Mitotic Spindle Checkpoint (Homo sapiens)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
Binding of the MCC complex to the APC/C complex (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Separation of Sister Chromatids (Homo sapiens)
Association of Securin with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Regulation of mitotic cell cycle (Homo sapiens)
APC/C-mediated degradation of cell cycle proteins (Homo sapiens)
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 (Homo sapiens)
Association of cell cycle proteins with the APC/C:Cdh1 complex (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated cell cycle proteins (Homo sapiens)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Ubiquitination of cell cycle proteins targeted by the APC/C:Cdh1complex (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
multiubiquitinated cell cycle protein:APC/C:Cdh1 complex [cytosol] (Homo sapiens)
cell cycle proteins:phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of mitotic proteins (Homo sapiens)
APC/C:Cdc20 mediated degradation of Cyclin B (Homo sapiens)
Association of Cyclin B:Cdc2 with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Cyclin B (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Ubiquitination of Cyclin B by phospho-APC/C:Cdc20 complex (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin B:Cdc2:Cdc20:phospho-APC/C complex [cytosol] (Homo sapiens)
Cdc20:phospho-APC/C:Cyclin B:Cdc2 complex [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
APC/C:Cdc20 mediated degradation of Securin (Homo sapiens)
Association of Securin with Cdc20:APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Securin (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Ubiquitination of Securin by phospho-APC/C:Cdc20 complex (Homo sapiens)
CDC20:p-APC/C:PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
CDC20:pAPC/C:K11polyUb-PTTG1 [cytosol] (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint (Homo sapiens)
APC-Cdc20 mediated degradation of Nek2A (Homo sapiens)
Association of Nek2A with MCC:APC/C (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Degradation of multiubiquitinated Nek2A (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Multiubiquitination of Nek2A (Homo sapiens)
Multiubiquitinated Nek2A [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Nek2A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Cdc20:Phospho-APC/C mediated degradation of Cyclin A (Homo sapiens)
Association of Cyclin A with the APC/C (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Degradation multiubiquitinated Cyclin A (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Ubiquitination of Cyclin A by APC/C:Cdc20 complex (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
multiubiquitinated Cyclin A associated with MCC:APC/C complex [cytosol] (Homo sapiens)
Cdc2:Cyclin A:MCC:APC/C complex [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Activation of APC/C:Cdc20 by dissociation of Cdc20:phospho-APC/C from Cdc20:phospho-APC/C:Mad2:Bub3:BubR1 (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase (Homo sapiens)
Association of Cdh1 with the APC/C (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Dissociation of Cdc20 from APC/C complex (Homo sapiens)
CDC20:p-APC/C [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Regulation of APC/C activators between G1/S and early anaphase (Homo sapiens)
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components (Homo sapiens)
Inactivation of APC/C via direct inhibition of the APC/C complex (Homo sapiens)
Binding of the MCC complex to the APC/C complex (Homo sapiens)
MCC:APC/C complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
S Phase (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
DNA Replication (Homo sapiens)
Synthesis of DNA (Homo sapiens)
Switching of origins to a post-replicative state (Homo sapiens)
CDK-mediated phosphorylation and removal of Cdc6 (Homo sapiens)
Cytoplasmic phosphorylated Cdc6 is ubiquitinated by the anaphase-promoting complex (Homo sapiens)
phospho-APC/C:Cdh1 complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
Interaction of E3 with substrate and E2-Ub complex (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Release of E3 from polyubiquitinated substrate (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
E3:K48-polyubiquitinated substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Ag-substrate:E3:E2:Ub [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
E3:Ub:substrate [cytosol] (Homo sapiens)
E3 ligases in proteasomal degradation [cytosol] (Homo sapiens)
APC/C E3 ligase complex [cytosol] (Homo sapiens)
ANAPC5 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UJX4 ANAPC5
Gene Names
ANAPC5, APC5
Chain
chain:1-755
Reference Genes
BioGPS Gene:51433 ANAPC5
COSMIC (genes):ANAPC5 ANAPC5
CTD Gene:51433 ANAPC5
dbSNP Gene:51433 ANAPC5
ENSEMBL:ENSG00000089053 ANAPC5
HGNC:15713 ANAPC5
KEGG:hsa:51433 ANAPC5
Monarch:51433 ANAPC5
NCBI Gene:51433 ANAPC5
OMIM:606948 ANAPC5
UCSC:Q9UJX4 ANAPC5
Reference Transcript
RefSeq:NM_001330489.1 ANAPC5
RefSeq:NM_016237.4 ANAPC5
RefSeq:NM_001137559.1 ANAPC5
Other Identifiers
11715599_a_at
16651927
16651929
16651967
16651969
16651971
16651975
16651977
16651979
16651981
16651983
16652011
16652013
16652081
16652591
16652593
16652631
16652633
16652635
16652639
16652641
16652643
16652645
16652647
16652675
16652677
16771463
18670994
18670995
18670996
18670997
18670998
18670999
18671000
18671001
18671002
18671003
18671004
18671005
18671006
18671007
18671008
18671009
18671010
18671011
18671012
18671013
18671014
18671015
18671016
18671017
18671018
18671019
18671020
18671021
18671022
18671023
18671024
18671025
18671026
18671027
18671028
200098_PM_s_at
200098_s_at
208721_PM_s_at
208721_s_at
208722_PM_s_at
208722_s_at
211036_PM_x_at
211036_x_at
235926_PM_at
235926_at
239651_PM_at
239651_at
3474936
3474937
3474938
3474939
3474940
3474941
3474942
3474943
3474947
3474948
3474949
3474950
3474951
3474952
3474953
3474956
3474957
3474958
3474959
3474960
3474961
3474962
3474963
3474964
3474965
3474966
3474967
3474968
3474969
3474970
3474971
3474972
3474973
3474974
3474975
3474976
3474977
3474978
3474979
3474980
3474981
3474982
3474983
3474984
3474985
3475040
3475042
3475044
3475046
3475048
3475050
3475072
3475074
3475076
3475078
3475096
3475098
3475100
3475106
3475108
3475110
3475112
3475114
3475116
3475148
3475150
3475152
3475154
3475178
35835_at
51433
56530_r_at
68060_at
7892634
7892775
7892908
7892964
7893097
7893148
7893346
7893415
7893501
7893529
7893593
7893717
7893761
7893821
7893856
7893862
7893908
7893948
7894095
7894176
7894232
7894295
7894316
7894574
7894665
7894711
7895027
7895032
7895042
7895065
7895338
7895432
7895438
7895548
7895658
7895803
7895856
7895978
7896071
7896192
7896205
7896241
7896269
7896299
7896336
7896562
7896627
7967149
83571_at
88272_at
90637_at
A_23_P204448
A_23_P377830
GE62916
GE79326
GE795975
GE85760
GO:0005515
GO:0005634
GO:0005654
GO:0005680
GO:0005737
GO:0005819
GO:0005829
GO:0005856
GO:0007346
GO:0016567
GO:0019903
GO:0030163
GO:0031145
GO:0043226
GO:0045842
GO:0051301
GO:0051445
GO:0070936
GO:0070979
GO:0141198
HMNXSV003049276
Hs.155766.0.A1_3p_at
Hs.189394.0.A1_3p_at
Hs.7101.0.S1_3p_s_at
ILMN_1723177
PH_hs_0000724
PH_hs_0009383
TC12002062.hg
g12654502_3p_s_at
Participates
as a component of
APC/C E3 ligase complex [cytosol] (Homo sapiens)
phosphorylated anaphase promoting complex (APC/C) [cytosol] (Homo sapiens)
Other forms of this molecule
ANAPC5 [nucleoplasm]
Inferred To
gfi-3 [cytosol]
(Caenorhabditis elegans)
Anapc5 [cytosol]
(Mus musculus)
Anapc5 [cytosol]
(Rattus norvegicus)
anapc5 [cytosol]
(Dictyostelium discoideum)
anapc5 [cytosol]
(Xenopus tropicalis)
ida [cytosol]
(Drosophila melanogaster)
ANAPC5 [cytosol]
(Bos taurus)
ANAPC5 [cytosol]
(Canis familiaris)
ANAPC5 [cytosol]
(Gallus gallus)
ANAPC5 [cytosol]
(Sus scrofa)
apc5 [cytosol]
(Schizosaccharomyces pombe)
APC5 [cytosol]
(Saccharomyces cerevisiae)
Cross References
RefSeq
NP_001131031.1
,
NP_057321.2
,
NP_001317418.1
OpenTargets
ENSG00000089053
ENSEMBL
ENSP00000261819
,
ENST00000261819
,
ENST00000441917
,
ENSP00000415061
HPA
ENSG00000089053-ANAPC5
PRO
Q9UJX4
Pharos - Targets
Q9UJX4
PDB
5KHR
,
8PKP
,
5G04
,
5G05
,
6TLJ
,
8TAR
,
8S4G
,
7QE7
,
5L9T
,
6Q6H
,
6TM5
,
6Q6G
,
6TNT
,
4UI9
,
5L9U
,
5A31
,
5LCW
,
8TAU
,
5KHU
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9JJ66
3
Cdc20 [nucleoplasm]
(R-MMU-6783069)
Cdc20 [nucleoplasm]
(R-MMU-174112)
Cdc20 [cytosol]
(R-MMU-141412)
0.564
2
UniProt:Q12834 CDC20
3
CDC20 [cytosol]
(R-HSA-141412)
CDC20 [nucleoplasm]
(R-HSA-174112)
PolyUb-CDC20 [nucleoplasm]
(R-HSA-6783069)
0.527
4
UniProt:Q9Y468 L3MBTL1
1
L3MBTL1 [nucleoplasm]
(R-HSA-3222110)
0.527
2
UniProt:O60566 BUB1B
1
BUB1B [cytosol]
(R-HSA-141436)
0.527
2
UniProt:P60484 PTEN
20
K48polyUb-PTEN [cytosol]
(R-HSA-8874327)
PolyUb-PTEN [nucleoplasm]
(R-HSA-6782515)
PTEN H93R [cytosol]
(R-HSA-2318524)
PTEN C124R [cytosol]
(R-HSA-2317439)
PTEN H93Y [cytosol]
(R-HSA-2318520)
PTEN R130G [cytosol]
(R-HSA-2317339)
PTEN H93D [cytosol]
(R-HSA-2318550)
PTEN R130L [cytosol]
(R-HSA-2317430)
PTEN H93A [cytosol]
(R-HSA-2318544)
PTEN G129E [cytosol]
(R-HSA-2318509)
PTEN S170N [cytosol]
(R-HSA-2318408)
PTEN R173P [cytosol]
(R-HSA-2317480)
PTEN R130Q [cytosol]
(R-HSA-2317416)
PTEN H93Q [cytosol]
(R-HSA-2318565)
PTEN G129R [cytosol]
(R-HSA-2318501)
PTEN H123Y [cytosol]
(R-HSA-2318469)
PTEN S170R [cytosol]
(R-HSA-2318437)
PTEN R173C [cytosol]
(R-HSA-2317478)
PTEN R173H [cytosol]
(R-HSA-2317473)
PTEN C124S [cytosol]
(R-HSA-2317379)
0.462
2
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