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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
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Analyse gene list
Analyse gene expression
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PYR [mitochondrial matrix]
Stable Identifier
R-ALL-113557
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Pyruvate, pyruvic acid, 2-Oxopropanoate, 2-Oxopropanoic acid, Pyroracemic acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Alanine metabolism (Bos taurus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Bos taurus)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Bos taurus)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Bos taurus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Bos taurus)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Bos taurus)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Bos taurus)
Degradation of cysteine and homocysteine (Bos taurus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Bos taurus)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Bos taurus)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Bos taurus)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Bos taurus)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PC catalyzes the carboxylation of PYR to form OA (Bos taurus)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Bos taurus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Bos taurus)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Bos taurus)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Bos taurus)
PYR [mitochondrial matrix]
Pyruvate metabolism (Bos taurus)
Regulation of pyruvate dehydrogenase (PDH) complex (Bos taurus)
PDK isoforms phosphorylate lipo-PDH (Bos taurus)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Bos taurus)
PYR [mitochondrial matrix]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
Signaling by Retinoic Acid (Bos taurus)
PDK isoforms phosphorylate lipo-PDH (Bos taurus)
PYR [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Alanine metabolism (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Caenorhabditis elegans)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Caenorhabditis elegans)
Degradation of cysteine and homocysteine (Caenorhabditis elegans)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Caenorhabditis elegans)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Caenorhabditis elegans)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PC catalyzes the carboxylation of PYR to form OA (Caenorhabditis elegans)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism and Citric Acid (TCA) cycle (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Pyruvate metabolism (Caenorhabditis elegans)
LDHAL6B reduces PYR to LACT (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Regulation of pyruvate dehydrogenase (PDH) complex (Caenorhabditis elegans)
PDK isoforms phosphorylate lipo-PDH (Caenorhabditis elegans)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
Signaling by Retinoic Acid (Caenorhabditis elegans)
PDK isoforms phosphorylate lipo-PDH (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Glyoxylate metabolism and glycine degradation (Canis familiaris)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Canis familiaris)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Canis familiaris)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Canis familiaris)
Degradation of cysteine and homocysteine (Canis familiaris)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Canis familiaris)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Canis familiaris)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Canis familiaris)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Canis familiaris)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
PC catalyzes the carboxylation of PYR to form OA (Canis familiaris)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Canis familiaris)
Pyruvate metabolism and Citric Acid (TCA) cycle (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Canis familiaris)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Canis familiaris)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Canis familiaris)
PYR [mitochondrial matrix]
Pyruvate metabolism (Canis familiaris)
Regulation of pyruvate dehydrogenase (PDH) complex (Canis familiaris)
PDK isoforms phosphorylate lipo-PDH (Canis familiaris)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Canis familiaris)
PYR [mitochondrial matrix]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
PDK isoforms phosphorylate lipo-PDH (Canis familiaris)
PYR [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Alanine metabolism (Danio rerio)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Danio rerio)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Danio rerio)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Danio rerio)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Danio rerio)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Danio rerio)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Danio rerio)
Degradation of cysteine and homocysteine (Danio rerio)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Danio rerio)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Danio rerio)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Danio rerio)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Danio rerio)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
PC catalyzes the carboxylation of PYR to form OA (Danio rerio)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Danio rerio)
Pyruvate metabolism and Citric Acid (TCA) cycle (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Danio rerio)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Danio rerio)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Danio rerio)
PYR [mitochondrial matrix]
Pyruvate metabolism (Danio rerio)
LDHAL6B reduces PYR to LACT (Danio rerio)
PYR [mitochondrial matrix]
Regulation of pyruvate dehydrogenase (PDH) complex (Danio rerio)
PDK isoforms phosphorylate lipo-PDH (Danio rerio)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Danio rerio)
PYR [mitochondrial matrix]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
Signaling by Retinoic Acid (Danio rerio)
PDK isoforms phosphorylate lipo-PDH (Danio rerio)
PYR [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Alanine metabolism (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Dictyostelium discoideum)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Dictyostelium discoideum)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Dictyostelium discoideum)
Degradation of cysteine and homocysteine (Dictyostelium discoideum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Dictyostelium discoideum)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Dictyostelium discoideum)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Dictyostelium discoideum)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Dictyostelium discoideum)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism and Citric Acid (TCA) cycle (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Dictyostelium discoideum)
PYR [mitochondrial matrix]
Pyruvate metabolism (Dictyostelium discoideum)
lipo-PDH decarboxylates PYR to Ac-CoA (Dictyostelium discoideum)
PYR [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Alanine metabolism (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Drosophila melanogaster)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Drosophila melanogaster)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
PC catalyzes the carboxylation of PYR to form OA (Drosophila melanogaster)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism and Citric Acid (TCA) cycle (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Drosophila melanogaster)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Drosophila melanogaster)
PYR [mitochondrial matrix]
Pyruvate metabolism (Drosophila melanogaster)
LDHAL6B reduces PYR to LACT (Drosophila melanogaster)
PYR [mitochondrial matrix]
Regulation of pyruvate dehydrogenase (PDH) complex (Drosophila melanogaster)
PDK isoforms phosphorylate lipo-PDH (Drosophila melanogaster)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Drosophila melanogaster)
PYR [mitochondrial matrix]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
PDK isoforms phosphorylate lipo-PDH (Drosophila melanogaster)
PYR [mitochondrial matrix]
Metabolism (Gallus gallus)
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
PYR [mitochondrial matrix]
Pyruvate metabolism (Gallus gallus)
pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (Gallus gallus)
PYR [mitochondrial matrix]
pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] (Gallus gallus)
PYR [mitochondrial matrix]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
Signaling by Retinoic Acid (Gallus gallus)
PDK isoforms phosphorylate lipo-PDH (Gallus gallus)
PYR [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Alanine metabolism (Homo sapiens)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Homo sapiens)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Homo sapiens)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Homo sapiens)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Homo sapiens)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Homo sapiens)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Homo sapiens)
Degradation of cysteine and homocysteine (Homo sapiens)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Homo sapiens)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Homo sapiens)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Homo sapiens)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Homo sapiens)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
PC catalyzes the carboxylation of PYR to form OA (Homo sapiens)
PYR [mitochondrial matrix]
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Pyrimidine catabolism (Homo sapiens)
(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine (Homo sapiens)
PYR [mitochondrial matrix]
beta-alanine + pyruvate => 3-oxopropanoate + alanine (Homo sapiens)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Homo sapiens)
Pyruvate metabolism and Citric Acid (TCA) cycle (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Homo sapiens)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)
PYR [mitochondrial matrix]
Pyruvate metabolism (Homo sapiens)
LDHAL6B reduces PYR to LACT (Homo sapiens)
PYR [mitochondrial matrix]
MPC1:MPC2 cotransports PYR, H+ from cytosol to mitochondrial matrix (Homo sapiens)
PYR [mitochondrial matrix]
Regulation of pyruvate dehydrogenase (PDH) complex (Homo sapiens)
PDK isoforms phosphorylate lipo-PDH (Homo sapiens)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Homo sapiens)
PYR [mitochondrial matrix]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
PDK isoforms phosphorylate lipo-PDH (Homo sapiens)
PYR [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Alanine metabolism (Mus musculus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Mus musculus)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Mus musculus)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Mus musculus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Mus musculus)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Mus musculus)
Degradation of cysteine and homocysteine (Mus musculus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Mus musculus)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Mus musculus)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Mus musculus)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Mus musculus)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
PC catalyzes the carboxylation of PYR to form OA (Mus musculus)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Mus musculus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Mus musculus)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Mus musculus)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Mus musculus)
PYR [mitochondrial matrix]
Pyruvate metabolism (Mus musculus)
LDHAL6B reduces PYR to LACT (Mus musculus)
PYR [mitochondrial matrix]
Regulation of pyruvate dehydrogenase (PDH) complex (Mus musculus)
PDK isoforms phosphorylate lipo-PDH (Mus musculus)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Mus musculus)
PYR [mitochondrial matrix]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
PDK isoforms phosphorylate lipo-PDH (Mus musculus)
PYR [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Sulfur amino acid metabolism (Plasmodium falciparum)
Degradation of cysteine and homocysteine (Plasmodium falciparum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Plasmodium falciparum)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Plasmodium falciparum)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Plasmodium falciparum)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Plasmodium falciparum)
PYR [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Alanine metabolism (Rattus norvegicus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Rattus norvegicus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Rattus norvegicus)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Rattus norvegicus)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Rattus norvegicus)
Degradation of cysteine and homocysteine (Rattus norvegicus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Rattus norvegicus)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Rattus norvegicus)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Rattus norvegicus)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
PC catalyzes the carboxylation of PYR to form OA (Rattus norvegicus)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
Pyruvate metabolism (Rattus norvegicus)
Regulation of pyruvate dehydrogenase (PDH) complex (Rattus norvegicus)
PDK isoforms phosphorylate lipo-PDH (Rattus norvegicus)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Rattus norvegicus)
PYR [mitochondrial matrix]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
PDK isoforms phosphorylate lipo-PDH (Rattus norvegicus)
PYR [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Alanine metabolism (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Saccharomyces cerevisiae)
Degradation of cysteine and homocysteine (Saccharomyces cerevisiae)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
PC catalyzes the carboxylation of PYR to form OA (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism and Citric Acid (TCA) cycle (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Pyruvate metabolism (Saccharomyces cerevisiae)
lipo-PDH decarboxylates PYR to Ac-CoA (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Alanine metabolism (Schizosaccharomyces pombe)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Schizosaccharomyces pombe)
Degradation of cysteine and homocysteine (Schizosaccharomyces pombe)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
PC catalyzes the carboxylation of PYR to form OA (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism and Citric Acid (TCA) cycle (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Pyruvate metabolism (Schizosaccharomyces pombe)
Regulation of pyruvate dehydrogenase (PDH) complex (Schizosaccharomyces pombe)
PDK isoforms phosphorylate lipo-PDH (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
Signaling by Retinoic Acid (Schizosaccharomyces pombe)
PDK isoforms phosphorylate lipo-PDH (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Alanine metabolism (Sus scrofa)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Sus scrofa)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Sus scrofa)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Sus scrofa)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Sus scrofa)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Sus scrofa)
Degradation of cysteine and homocysteine (Sus scrofa)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Sus scrofa)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Sus scrofa)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Sus scrofa)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Sus scrofa)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
PC catalyzes the carboxylation of PYR to form OA (Sus scrofa)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Sus scrofa)
Pyruvate metabolism and Citric Acid (TCA) cycle (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Sus scrofa)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Sus scrofa)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Sus scrofa)
PYR [mitochondrial matrix]
Pyruvate metabolism (Sus scrofa)
Regulation of pyruvate dehydrogenase (PDH) complex (Sus scrofa)
PDK isoforms phosphorylate lipo-PDH (Sus scrofa)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Sus scrofa)
PYR [mitochondrial matrix]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
Signaling by Retinoic Acid (Sus scrofa)
PDK isoforms phosphorylate lipo-PDH (Sus scrofa)
PYR [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Alanine metabolism (Xenopus tropicalis)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Xenopus tropicalis)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Xenopus tropicalis)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Xenopus tropicalis)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Xenopus tropicalis)
Degradation of cysteine and homocysteine (Xenopus tropicalis)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Xenopus tropicalis)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Xenopus tropicalis)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Xenopus tropicalis)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
PC catalyzes the carboxylation of PYR to form OA (Xenopus tropicalis)
PYR [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism and Citric Acid (TCA) cycle (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
Pyruvate metabolism (Xenopus tropicalis)
LDHAL6B reduces PYR to LACT (Xenopus tropicalis)
PYR [mitochondrial matrix]
Regulation of pyruvate dehydrogenase (PDH) complex (Xenopus tropicalis)
PDK isoforms phosphorylate lipo-PDH (Xenopus tropicalis)
PYR [mitochondrial matrix]
lipo-PDH decarboxylates PYR to Ac-CoA (Xenopus tropicalis)
PYR [mitochondrial matrix]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
Signaling by Retinoic Acid (Xenopus tropicalis)
PDK isoforms phosphorylate lipo-PDH (Xenopus tropicalis)
PYR [mitochondrial matrix]
External Reference Information
External Reference
pyruvate [ChEBI:15361]
Participates
as an input of
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (Gallus gallus)
LDHAL6B reduces PYR to LACT (Caenorhabditis elegans)
LDHAL6B reduces PYR to LACT (Drosophila melanogaster)
LDHAL6B reduces PYR to LACT (Gallus gallus)
LDHAL6B reduces PYR to LACT (Xenopus tropicalis)
LDHAL6B reduces PYR to LACT (Danio rerio)
LDHAL6B reduces PYR to LACT (Mus musculus)
LDHAL6B reduces PYR to LACT (Homo sapiens)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Schizosaccharomyces pombe)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Gallus gallus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Xenopus tropicalis)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Danio rerio)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Sus scrofa)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Bos taurus)
PC catalyzes the carboxylation of PYR to form OA (Mus musculus)
PC catalyzes the carboxylation of PYR to form OA (Homo sapiens)
PC catalyzes the carboxylation of PYR to form OA (Rattus norvegicus)
PC catalyzes the carboxylation of PYR to form OA (Canis familiaris)
PC catalyzes the carboxylation of PYR to form OA (Bos taurus)
PC catalyzes the carboxylation of PYR to form OA (Sus scrofa)
PC catalyzes the carboxylation of PYR to form OA (Danio rerio)
PC catalyzes the carboxylation of PYR to form OA (Drosophila melanogaster)
PC catalyzes the carboxylation of PYR to form OA (Caenorhabditis elegans)
PC catalyzes the carboxylation of PYR to form OA (Schizosaccharomyces pombe)
PC catalyzes the carboxylation of PYR to form OA (Saccharomyces cerevisiae)
lipo-PDH decarboxylates PYR to Ac-CoA (Homo sapiens)
lipo-PDH decarboxylates PYR to Ac-CoA (Mus musculus)
lipo-PDH decarboxylates PYR to Ac-CoA (Rattus norvegicus)
lipo-PDH decarboxylates PYR to Ac-CoA (Canis familiaris)
lipo-PDH decarboxylates PYR to Ac-CoA (Bos taurus)
lipo-PDH decarboxylates PYR to Ac-CoA (Sus scrofa)
lipo-PDH decarboxylates PYR to Ac-CoA (Danio rerio)
lipo-PDH decarboxylates PYR to Ac-CoA (Xenopus tropicalis)
lipo-PDH decarboxylates PYR to Ac-CoA (Gallus gallus)
lipo-PDH decarboxylates PYR to Ac-CoA (Drosophila melanogaster)
lipo-PDH decarboxylates PYR to Ac-CoA (Caenorhabditis elegans)
lipo-PDH decarboxylates PYR to Ac-CoA (Dictyostelium discoideum)
lipo-PDH decarboxylates PYR to Ac-CoA (Schizosaccharomyces pombe)
lipo-PDH decarboxylates PYR to Ac-CoA (Saccharomyces cerevisiae)
PC catalyzes the carboxylation of PYR to form OA (Xenopus tropicalis)
(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine (Homo sapiens)
(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine (Rattus norvegicus)
beta-alanine + pyruvate => 3-oxopropanoate + alanine (Homo sapiens)
beta-alanine + pyruvate => 3-oxopropanoate + alanine (Rattus norvegicus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Homo sapiens)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Mus musculus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)
as an output of
pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] (Gallus gallus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Dictyostelium discoideum)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Caenorhabditis elegans)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Drosophila melanogaster)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Gallus gallus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Xenopus tropicalis)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Danio rerio)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Sus scrofa)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Bos taurus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Canis familiaris)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Rattus norvegicus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Mus musculus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Homo sapiens)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Caenorhabditis elegans)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Drosophila melanogaster)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Gallus gallus)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Xenopus tropicalis)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Danio rerio)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Sus scrofa)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Bos taurus)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Canis familiaris)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Rattus norvegicus)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Mus musculus)
ME3:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Xenopus tropicalis)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Danio rerio)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Sus scrofa)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Bos taurus)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Canis familiaris)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Rattus norvegicus)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Mus musculus)
ME2:Mg2+ tetramer oxidatively decarboxylates MAL to PYR (Homo sapiens)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Plasmodium falciparum)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Saccharomyces cerevisiae)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Schizosaccharomyces pombe)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Dictyostelium discoideum)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Caenorhabditis elegans)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Gallus gallus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Xenopus tropicalis)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Sus scrofa)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Bos taurus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Canis familiaris)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Rattus norvegicus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Mus musculus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Homo sapiens)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Danio rerio)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Plasmodium falciparum)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Saccharomyces cerevisiae)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Schizosaccharomyces pombe)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Dictyostelium discoideum)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Caenorhabditis elegans)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Gallus gallus)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Xenopus tropicalis)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Sus scrofa)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Bos taurus)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Canis familiaris)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Rattus norvegicus)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Mus musculus)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Homo sapiens)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Danio rerio)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Plasmodium falciparum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Saccharomyces cerevisiae)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Schizosaccharomyces pombe)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Dictyostelium discoideum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Caenorhabditis elegans)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Gallus gallus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Xenopus tropicalis)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Danio rerio)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Sus scrofa)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Bos taurus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Canis familiaris)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Rattus norvegicus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Mus musculus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Homo sapiens)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Plasmodium falciparum)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Saccharomyces cerevisiae)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Schizosaccharomyces pombe)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Dictyostelium discoideum)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Caenorhabditis elegans)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Gallus gallus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Xenopus tropicalis)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Sus scrofa)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Bos taurus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Canis familiaris)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Rattus norvegicus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Mus musculus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Homo sapiens)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Danio rerio)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Caenorhabditis elegans)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Drosophila melanogaster)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Gallus gallus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Xenopus tropicalis)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Sus scrofa)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Bos taurus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Canis familiaris)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Rattus norvegicus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Mus musculus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Homo sapiens)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Danio rerio)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Schizosaccharomyces pombe)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Gallus gallus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Xenopus tropicalis)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Bos taurus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Rattus norvegicus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Mus musculus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Homo sapiens)
MPC1:MPC2 cotransports PYR, H+ from cytosol to mitochondrial matrix (Homo sapiens)
Cytosolic PYR is transported to the mitochondrial matrix (Rattus norvegicus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Homo sapiens)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Rattus norvegicus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Canis familiaris)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Bos taurus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Sus scrofa)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Danio rerio)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Gallus gallus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Danio rerio)
This entity regulates
Negatively
PDK isoforms phosphorylate lipo-PDH
(Schizosaccharomyces pombe)
PDK isoforms phosphorylate lipo-PDH
(Caenorhabditis elegans)
PDK isoforms phosphorylate lipo-PDH
(Drosophila melanogaster)
PDK isoforms phosphorylate lipo-PDH
(Gallus gallus)
PDK isoforms phosphorylate lipo-PDH
(Xenopus tropicalis)
PDK isoforms phosphorylate lipo-PDH
(Danio rerio)
PDK isoforms phosphorylate lipo-PDH
(Sus scrofa)
PDK isoforms phosphorylate lipo-PDH
(Bos taurus)
PDK isoforms phosphorylate lipo-PDH
(Canis familiaris)
PDK isoforms phosphorylate lipo-PDH
(Rattus norvegicus)
PDK isoforms phosphorylate lipo-PDH
(Mus musculus)
PDK isoforms phosphorylate lipo-PDH
(Homo sapiens)
Other forms of this molecule
PYR [cytoplasm]
pyruvic acid [cytosol]
PYR [extracellular region]
PYR [peroxisomal matrix]
PYR [cytosol]
PYR [mitochondrial intermembrane space]
Cross References
KNApSAcK
C00001200
AraCyc
PYRUVATE
CAS
127-17-3
COMPOUND
C00022
PubChem Compound
107735
UMBBD
c0159
ZINC
000001532517
KEGG Gene
C00022
,
c00022
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![PYR [mitochondrial matrix] icon](/icon/R-ICO-013265.svg){kind=icon}
