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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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FAQ
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Analyse gene expression
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PYR [mitochondrial matrix]
Stable Identifier
R-ALL-113557
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Pyruvate, pyruvic acid, 2-Oxopropanoate, 2-Oxopropanoic acid, Pyroracemic acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Pyruvate metabolism (Bos taurus)
FAHD1 dimer hydrolyses OA to PYR (Bos taurus)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Bos taurus)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Bos taurus)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Bos taurus)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Bos taurus)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Bos taurus)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Bos taurus)
Regulation of pyruvate dehydrogenase (PDH) complex (Bos taurus)
PDK isozymes phosphorylate PDHC subunit E1 (Bos taurus)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Bos taurus)
Alanine metabolism (Bos taurus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Bos taurus)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Bos taurus)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Bos taurus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Bos taurus)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Bos taurus)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Bos taurus)
Degradation of cysteine and homocysteine (Bos taurus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Bos taurus)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Bos taurus)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Bos taurus)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Bos taurus)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PC carboxylates PYR to OA (Bos taurus)
PYR [mitochondrial matrix]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
Signaling by Retinoic Acid (Bos taurus)
PDK isozymes phosphorylate PDHC subunit E1 (Bos taurus)
PYR [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
FAHD1 dimer hydrolyses OA to PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Caenorhabditis elegans)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Caenorhabditis elegans)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Caenorhabditis elegans)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Caenorhabditis elegans)
Regulation of pyruvate dehydrogenase (PDH) complex (Caenorhabditis elegans)
PDK isozymes phosphorylate PDHC subunit E1 (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Alanine metabolism (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Caenorhabditis elegans)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Caenorhabditis elegans)
Degradation of cysteine and homocysteine (Caenorhabditis elegans)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Caenorhabditis elegans)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Caenorhabditis elegans)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Caenorhabditis elegans)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PC carboxylates PYR to OA (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
Signaling by Retinoic Acid (Caenorhabditis elegans)
PDK isozymes phosphorylate PDHC subunit E1 (Caenorhabditis elegans)
PYR [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
FAHD1 dimer hydrolyses OA to PYR (Canis familiaris)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Canis familiaris)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Canis familiaris)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Canis familiaris)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Canis familiaris)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Canis familiaris)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Canis familiaris)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Canis familiaris)
Regulation of pyruvate dehydrogenase (PDH) complex (Canis familiaris)
PDK isozymes phosphorylate PDHC subunit E1 (Canis familiaris)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Canis familiaris)
Alanine metabolism (Canis familiaris)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Canis familiaris)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Canis familiaris)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Canis familiaris)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Canis familiaris)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Canis familiaris)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Canis familiaris)
Degradation of cysteine and homocysteine (Canis familiaris)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Canis familiaris)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Canis familiaris)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Canis familiaris)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Canis familiaris)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
PC carboxylates PYR to OA (Canis familiaris)
PYR [mitochondrial matrix]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
PDK isozymes phosphorylate PDHC subunit E1 (Canis familiaris)
PYR [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Pyruvate metabolism (Danio rerio)
FAHD1 dimer hydrolyses OA to PYR (Danio rerio)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Danio rerio)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Danio rerio)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Danio rerio)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Danio rerio)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Danio rerio)
Glyoxylate metabolism and glycine degradation (Danio rerio)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Danio rerio)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Danio rerio)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Danio rerio)
Degradation of cysteine and homocysteine (Danio rerio)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Danio rerio)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Danio rerio)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Danio rerio)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Danio rerio)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
PC carboxylates PYR to OA (Danio rerio)
PYR [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism (Dictyostelium discoideum)
FAHD1 dimer hydrolyses OA to PYR (Dictyostelium discoideum)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Dictyostelium discoideum)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Dictyostelium discoideum)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Alanine metabolism (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Dictyostelium discoideum)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Dictyostelium discoideum)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Dictyostelium discoideum)
Degradation of cysteine and homocysteine (Dictyostelium discoideum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Dictyostelium discoideum)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Dictyostelium discoideum)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Dictyostelium discoideum)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Dictyostelium discoideum)
PYR [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
FAHD1 dimer hydrolyses OA to PYR (Drosophila melanogaster)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Drosophila melanogaster)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Drosophila melanogaster)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Drosophila melanogaster)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Drosophila melanogaster)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Drosophila melanogaster)
Regulation of pyruvate dehydrogenase (PDH) complex (Drosophila melanogaster)
PDK isozymes phosphorylate PDHC subunit E1 (Drosophila melanogaster)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Alanine metabolism (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Drosophila melanogaster)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Drosophila melanogaster)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
PC carboxylates PYR to OA (Drosophila melanogaster)
PYR [mitochondrial matrix]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
PDK isozymes phosphorylate PDHC subunit E1 (Drosophila melanogaster)
PYR [mitochondrial matrix]
Metabolism (Gallus gallus)
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
PYR [mitochondrial matrix]
Pyruvate metabolism (Gallus gallus)
pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (Gallus gallus)
PYR [mitochondrial matrix]
pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] (Gallus gallus)
PYR [mitochondrial matrix]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
Signaling by Retinoic Acid (Gallus gallus)
PDK isozymes phosphorylate PDHC subunit E1 (Gallus gallus)
PYR [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
FAHD1 dimer hydrolyses OA to PYR (Homo sapiens)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Homo sapiens)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Homo sapiens)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Homo sapiens)
PYR [mitochondrial matrix]
MPC1:MPC2 imports PYR, H+ to mitochondrial matrix (Homo sapiens)
PYR [mitochondrial matrix]
Mitochondrial H2O2 decarboxylates PYR to acetate (Homo sapiens)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Homo sapiens)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Homo sapiens)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Homo sapiens)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Homo sapiens)
Regulation of pyruvate dehydrogenase (PDH) complex (Homo sapiens)
PDK isozymes phosphorylate PDHC subunit E1 (Homo sapiens)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Homo sapiens)
Alanine metabolism (Homo sapiens)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Homo sapiens)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Homo sapiens)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Homo sapiens)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Homo sapiens)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Homo sapiens)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Homo sapiens)
Degradation of cysteine and homocysteine (Homo sapiens)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Homo sapiens)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Homo sapiens)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Homo sapiens)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Homo sapiens)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
PC carboxylates PYR to OA (Homo sapiens)
PYR [mitochondrial matrix]
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Pyrimidine catabolism (Homo sapiens)
(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine (Homo sapiens)
PYR [mitochondrial matrix]
beta-alanine + pyruvate => 3-oxopropanoate + alanine (Homo sapiens)
PYR [mitochondrial matrix]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
PDK isozymes phosphorylate PDHC subunit E1 (Homo sapiens)
PYR [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
FAHD1 dimer hydrolyses OA to PYR (Mus musculus)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Mus musculus)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Mus musculus)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Mus musculus)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Mus musculus)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Mus musculus)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Mus musculus)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Mus musculus)
Regulation of pyruvate dehydrogenase (PDH) complex (Mus musculus)
PDK isozymes phosphorylate PDHC subunit E1 (Mus musculus)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Mus musculus)
Alanine metabolism (Mus musculus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Mus musculus)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Mus musculus)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Mus musculus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Mus musculus)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Mus musculus)
Degradation of cysteine and homocysteine (Mus musculus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Mus musculus)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Mus musculus)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Mus musculus)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Mus musculus)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
PC carboxylates PYR to OA (Mus musculus)
PYR [mitochondrial matrix]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
PDK isozymes phosphorylate PDHC subunit E1 (Mus musculus)
PYR [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Sulfur amino acid metabolism (Plasmodium falciparum)
Degradation of cysteine and homocysteine (Plasmodium falciparum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Plasmodium falciparum)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Plasmodium falciparum)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Plasmodium falciparum)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Plasmodium falciparum)
PYR [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
FAHD1 dimer hydrolyses OA to PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Rattus norvegicus)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Rattus norvegicus)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Rattus norvegicus)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Rattus norvegicus)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Rattus norvegicus)
Regulation of pyruvate dehydrogenase (PDH) complex (Rattus norvegicus)
PDK isozymes phosphorylate PDHC subunit E1 (Rattus norvegicus)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Alanine metabolism (Rattus norvegicus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Rattus norvegicus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Rattus norvegicus)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Rattus norvegicus)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Rattus norvegicus)
Degradation of cysteine and homocysteine (Rattus norvegicus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Rattus norvegicus)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Rattus norvegicus)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Rattus norvegicus)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Rattus norvegicus)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
PC carboxylates PYR to OA (Rattus norvegicus)
PYR [mitochondrial matrix]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
PDK isozymes phosphorylate PDHC subunit E1 (Rattus norvegicus)
PYR [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism (Saccharomyces cerevisiae)
FAHD1 dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Saccharomyces cerevisiae)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Alanine metabolism (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Saccharomyces cerevisiae)
Degradation of cysteine and homocysteine (Saccharomyces cerevisiae)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
PYR [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism (Schizosaccharomyces pombe)
FAHD1 dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Schizosaccharomyces pombe)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Schizosaccharomyces pombe)
Regulation of pyruvate dehydrogenase (PDH) complex (Schizosaccharomyces pombe)
PDK isozymes phosphorylate PDHC subunit E1 (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Glyoxylate metabolism and glycine degradation (Schizosaccharomyces pombe)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Schizosaccharomyces pombe)
Degradation of cysteine and homocysteine (Schizosaccharomyces pombe)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
Signaling by Retinoic Acid (Schizosaccharomyces pombe)
PDK isozymes phosphorylate PDHC subunit E1 (Schizosaccharomyces pombe)
PYR [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
FAHD1 dimer hydrolyses OA to PYR (Sus scrofa)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Sus scrofa)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Sus scrofa)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Sus scrofa)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Sus scrofa)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Sus scrofa)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Sus scrofa)
Regulation of pyruvate dehydrogenase (PDH) complex (Sus scrofa)
PDK isozymes phosphorylate PDHC subunit E1 (Sus scrofa)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Sus scrofa)
Alanine metabolism (Sus scrofa)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Sus scrofa)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Sus scrofa)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Sus scrofa)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Sus scrofa)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Sus scrofa)
Degradation of cysteine and homocysteine (Sus scrofa)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Sus scrofa)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Sus scrofa)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Sus scrofa)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Sus scrofa)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
PC carboxylates PYR to OA (Sus scrofa)
PYR [mitochondrial matrix]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
Signaling by Retinoic Acid (Sus scrofa)
PDK isozymes phosphorylate PDHC subunit E1 (Sus scrofa)
PYR [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
FAHD1 dimer hydrolyses OA to PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
LDHAL6B reduces PYR to LACT (Xenopus tropicalis)
PYR [mitochondrial matrix]
ME2 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
ME3 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
PC carboxylates PYR to OA (Xenopus tropicalis)
PYR [mitochondrial matrix]
PDH complex synthesizes acetyl-CoA from PYR (Xenopus tropicalis)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Xenopus tropicalis)
PYR [mitochondrial matrix]
Regulation of pyruvate metabolism (Xenopus tropicalis)
Regulation of pyruvate dehydrogenase (PDH) complex (Xenopus tropicalis)
PDK isozymes phosphorylate PDHC subunit E1 (Xenopus tropicalis)
PYR [mitochondrial matrix]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Alanine metabolism (Xenopus tropicalis)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Xenopus tropicalis)
PYR [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Xenopus tropicalis)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Xenopus tropicalis)
PYR [mitochondrial matrix]
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Xenopus tropicalis)
PYR [mitochondrial matrix]
Sulfur amino acid metabolism (Xenopus tropicalis)
Degradation of cysteine and homocysteine (Xenopus tropicalis)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Xenopus tropicalis)
PYR [mitochondrial matrix]
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Xenopus tropicalis)
PYR [mitochondrial matrix]
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Xenopus tropicalis)
PYR [mitochondrial matrix]
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Xenopus tropicalis)
PYR [mitochondrial matrix]
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
PC carboxylates PYR to OA (Xenopus tropicalis)
PYR [mitochondrial matrix]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
Signaling by Retinoic Acid (Xenopus tropicalis)
PDK isozymes phosphorylate PDHC subunit E1 (Xenopus tropicalis)
PYR [mitochondrial matrix]
External Reference Information
External Reference
pyruvate [ChEBI:15361]
Participates
as an input of
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
pyruvate + CoASH + NAD+ => acetylCoA + CO2 + NADH + H+ (Gallus gallus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Gallus gallus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Xenopus tropicalis)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Sus scrofa)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Bos taurus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Canis familiaris)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Rattus norvegicus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Mus musculus)
PXLP-K341-GPT2 transaminates PYR to form L-Ala (Homo sapiens)
Mitochondrial H2O2 decarboxylates PYR to acetate (Homo sapiens)
beta-alanine + pyruvate => 3-oxopropanoate + alanine (Rattus norvegicus)
beta-alanine + pyruvate => 3-oxopropanoate + alanine (Homo sapiens)
(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine (Rattus norvegicus)
(R)-3-aminoisobutyric acid + pyruvate => 2-methyl-3-oxopropanoate + alanine (Homo sapiens)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Rattus norvegicus)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Mus musculus)
LDHAL6B reduces PYR to LACT (Caenorhabditis elegans)
LDHAL6B reduces PYR to LACT (Drosophila melanogaster)
LDHAL6B reduces PYR to LACT (Gallus gallus)
LDHAL6B reduces PYR to LACT (Xenopus tropicalis)
LDHAL6B reduces PYR to LACT (Danio rerio)
LDHAL6B reduces PYR to LACT (Canis familiaris)
LDHAL6B reduces PYR to LACT (Rattus norvegicus)
LDHAL6B reduces PYR to LACT (Mus musculus)
LDHAL6B reduces PYR to LACT (Homo sapiens)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Dictyostelium discoideum)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Gallus gallus)
PC carboxylates PYR to OA (Rattus norvegicus)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Homo sapiens)
PC carboxylates PYR to OA (Bos taurus)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Bos taurus)
PC carboxylates PYR to OA (Canis familiaris)
PC carboxylates PYR to OA (Homo sapiens)
PC carboxylates PYR to OA (Mus musculus)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Canis familiaris)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Sus scrofa)
PC carboxylates PYR to OA (Sus scrofa)
PC carboxylates PYR to OA (Danio rerio)
PC carboxylates PYR to OA (Xenopus tropicalis)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Xenopus tropicalis)
PC carboxylates PYR to OA (Drosophila melanogaster)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Drosophila melanogaster)
PC carboxylates PYR to OA (Caenorhabditis elegans)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Caenorhabditis elegans)
PC carboxylates PYR to OA (Schizosaccharomyces pombe)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Schizosaccharomyces pombe)
PC carboxylates PYR to OA (Saccharomyces cerevisiae)
PDH E1 decarboxylates PYR, transferring acetyl to DLAT (Saccharomyces cerevisiae)
as an output of
pyruvate + H+ [cytosol] => pyruvate + H+ [mitochondrial matrix] (Gallus gallus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Saccharomyces cerevisiae)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Dictyostelium discoideum)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Caenorhabditis elegans)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Drosophila melanogaster)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Gallus gallus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Xenopus tropicalis)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Bos taurus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Canis familiaris)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Rattus norvegicus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Mus musculus)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Homo sapiens)
PXLP-K341-GPT2 transaminates L-Ala to form PYR (Sus scrofa)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Plasmodium falciparum)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Saccharomyces cerevisiae)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Schizosaccharomyces pombe)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Dictyostelium discoideum)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Caenorhabditis elegans)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Gallus gallus)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Xenopus tropicalis)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Danio rerio)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Sus scrofa)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Canis familiaris)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Rattus norvegicus)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Mus musculus)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Homo sapiens)
MPST transfers sulfur atom from 3MPYR to form CysS248-MPST (Bos taurus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Plasmodium falciparum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Saccharomyces cerevisiae)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Schizosaccharomyces pombe)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Dictyostelium discoideum)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Caenorhabditis elegans)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Gallus gallus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Xenopus tropicalis)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Danio rerio)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Sus scrofa)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Canis familiaris)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Rattus norvegicus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Mus musculus)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Homo sapiens)
MPST transfers sulfur atom from 3MPYR to HSO3- to form S2O3(2-) and PYR (Bos taurus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Plasmodium falciparum)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Saccharomyces cerevisiae)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Schizosaccharomyces pombe)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Dictyostelium discoideum)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Caenorhabditis elegans)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Gallus gallus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Xenopus tropicalis)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Danio rerio)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Sus scrofa)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Canis familiaris)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Rattus norvegicus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Mus musculus)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Homo sapiens)
MPST transfers sulfur from 3MPYR to HCN to form HSCN (Bos taurus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Plasmodium falciparum)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Saccharomyces cerevisiae)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Schizosaccharomyces pombe)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Dictyostelium discoideum)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Caenorhabditis elegans)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Gallus gallus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Xenopus tropicalis)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Danio rerio)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Sus scrofa)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Canis familiaris)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Rattus norvegicus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Mus musculus)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Homo sapiens)
MPST transfers sulfur from sulfanegen to HCN to form HSCN (Bos taurus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Caenorhabditis elegans)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Drosophila melanogaster)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Gallus gallus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Xenopus tropicalis)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Danio rerio)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Sus scrofa)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Bos taurus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Canis familiaris)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Rattus norvegicus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Mus musculus)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Homo sapiens)
Mitochondrial AGXT2 tetramer transaminates glyoxylate and alanine to glycine and pyruvate (Schizosaccharomyces pombe)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Gallus gallus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Xenopus tropicalis)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Danio rerio)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Sus scrofa)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Bos taurus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Canis familiaris)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Rattus norvegicus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Mus musculus)
HOGA1 tetramer aldol-cleaves 4-OH-2-oxoglutarate (HOG) to glyoxylate and pyruvate (Homo sapiens)
Cytosolic PYR is transported to the mitochondrial matrix (Rattus norvegicus)
ME2 tetramer decarboxylates MAL to PYR (Bos taurus)
ME2 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
ME3 tetramer decarboxylates MAL to PYR (Bos taurus)
ME2 tetramer decarboxylates MAL to PYR (Mus musculus)
ME3 tetramer decarboxylates MAL to PYR (Canis familiaris)
FAHD1 dimer hydrolyses OA to PYR (Canis familiaris)
FAHD1 dimer hydrolyses OA to PYR (Rattus norvegicus)
ME3 tetramer decarboxylates MAL to PYR (Rattus norvegicus)
FAHD1 dimer hydrolyses OA to PYR (Mus musculus)
FAHD1 dimer hydrolyses OA to PYR (Dictyostelium discoideum)
ME3 tetramer decarboxylates MAL to PYR (Gallus gallus)
FAHD1 dimer hydrolyses OA to PYR (Gallus gallus)
FAHD1 dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
MPC1:MPC2 imports PYR, H+ to mitochondrial matrix (Homo sapiens)
FAHD1 dimer hydrolyses OA to PYR (Bos taurus)
FAHD1 dimer hydrolyses OA to PYR (Homo sapiens)
ME2 tetramer decarboxylates MAL to PYR (Canis familiaris)
ME2 tetramer decarboxylates MAL to PYR (Homo sapiens)
ME3 tetramer decarboxylates MAL to PYR (Homo sapiens)
ME3 tetramer decarboxylates MAL to PYR (Mus musculus)
ME3 tetramer decarboxylates MAL to PYR (Sus scrofa)
ME2 tetramer decarboxylates MAL to PYR (Sus scrofa)
FAHD1 dimer hydrolyses OA to PYR (Sus scrofa)
ME3 tetramer decarboxylates MAL to PYR (Danio rerio)
ME2 tetramer decarboxylates MAL to PYR (Danio rerio)
FAHD1 dimer hydrolyses OA to PYR (Danio rerio)
FAHD1 dimer hydrolyses OA to PYR (Xenopus tropicalis)
ME3 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)
ME2 tetramer decarboxylates MAL to PYR (Xenopus tropicalis)
ME2 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
FAHD1 dimer hydrolyses OA to PYR (Drosophila melanogaster)
ME3 tetramer decarboxylates MAL to PYR (Drosophila melanogaster)
FAHD1 dimer hydrolyses OA to PYR (Caenorhabditis elegans)
ME2 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
ME3 tetramer decarboxylates MAL to PYR (Caenorhabditis elegans)
FAHD1 dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
This entity regulates
Negatively
PDK isozymes phosphorylate PDHC subunit E1
(Schizosaccharomyces pombe)
PDK isozymes phosphorylate PDHC subunit E1
(Xenopus tropicalis)
PDK isozymes phosphorylate PDHC subunit E1
(Gallus gallus)
PDK isozymes phosphorylate PDHC subunit E1
(Sus scrofa)
PDK isozymes phosphorylate PDHC subunit E1
(Caenorhabditis elegans)
PDK isozymes phosphorylate PDHC subunit E1
(Drosophila melanogaster)
PDK isozymes phosphorylate PDHC subunit E1
(Bos taurus)
PDK isozymes phosphorylate PDHC subunit E1
(Canis familiaris)
PDK isozymes phosphorylate PDHC subunit E1
(Mus musculus)
PDK isozymes phosphorylate PDHC subunit E1
(Homo sapiens)
PDK isozymes phosphorylate PDHC subunit E1
(Rattus norvegicus)
Other forms of this molecule
PYR [cytoplasm]
pyruvic acid [cytosol]
PYR [extracellular region]
PYR [peroxisomal matrix]
PYR [cytosol]
PYR [mitochondrial intermembrane space]
Cross References
KNApSAcK
C00001200
AraCyc
PYRUVATE
CAS
127-17-3
COMPOUND
C00022
PubChem Compound
107735
UMBBD
c0159
ZINC
ZINC000001532517
KEGG Gene
C00022
,
c00022
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![PYR [mitochondrial matrix] icon](/icon/R-ICO-013265.svg){kind=icon}
