Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Schema
>
EntityWithAccessionedSequence
>
Entries
CDH1 gene [nucleoplasm]
Show undefined attributes
Go to Details
compartment
[Compartment:7660] nucleoplasm
componentOf
[Complex:R-HSA-9825718] p-S742 TBX3:CDH1 gene [nucleoplasm] - Homo sapiens
[Complex:R-HSA-9793459] ZEB1:CDH1 gene [nucleoplasm] - Homo sapiens
consumedByEvent
[BlackBoxEvent:R-HSA-9825774] SNAI2 and TBX3 repress CDH1 gene expression during melanocyte development - Homo sapiens
[BlackBoxEvent:R-HSA-9926527] MITF-M-dependent CDH1 gene expression - Homo sapiens
[BlackBoxEvent:R-HSA-9823995] Expression of E-cadherin (CDH1) in definitive endoderm - Homo sapiens
[BlackBoxEvent:R-HSA-9765049] TWIST1 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9767924] TCF12 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9768071] ZNF217 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9765293] ZEB2 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9764934] PRC2 (EZH2) mediates repression of CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9765175] TWIST2 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-NUL-9794433] Snai1 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9764752] SNAI1 represses CDH1 transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9767706] WT1 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9765756] TCF3 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9764778] ZEB1 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9764827] DNTTIP1 and KDM1A repress CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9768293] RB1 and TFAP2A stimulate CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9764800] SP1 stimulates CDH1 gene transcription - Homo sapiens
[Reaction:R-HSA-9764791] SP1 binds CDH1 gene promoter - Homo sapiens
[BlackBoxEvent:R-HSA-9765539] FOXJ2 stimulates CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9765330] KLF4 stimulates CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9765372] FOXA2 stimulates CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9768079] FOXQ1 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9766286] ARID1A and SWI/SNF complex stimulate CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9764863] KLF9 stimulates CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9768484] SNAI2 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9768511] CTBP1,CTBP2 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9767779] ZBTB33 represses CDH1 gene transcription - Homo sapiens
[BlackBoxEvent:R-HSA-9766065] PKM and TGIF2 repress CDH1 gene transcription - Homo sapiens
[Reaction:R-HSA-9825794] p-S742 TBX3 binds CDH1 promoter - Homo sapiens
[Reaction:R-HSA-9926495] MITF-M binds CDH1 gene - Homo sapiens
[Reaction:R-HSA-9756414] SNAI1 binds the CDH1 gene - Homo sapiens
[Reaction:R-HSA-9767922] TCF12 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9767700] WT1 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9765015] TWIST1 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9765313] ZEB2 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9764930] PRC2 (EZH2) core complex binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9765169] TWIST2 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9765742] TCF3 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9764741] ZEB1 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9764811] DNTTIP1 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9765542] FOXJ2 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9765326] KLF4 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9765371] FOXA2 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9768082] FOXQ1 bind CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9766293] ARID1A binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9764866] KLF9 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9768533] SNAI2 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9768477] CTBP1,CTBP2 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9767787] ZBTB33 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9768067] ZNF217 binds CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9766062] PKM and TGIF2 bind CDH1 gene promoter - Homo sapiens
[Reaction:R-HSA-9768288] RB1 and TFAP2A bind CDH1 gene promoter - Homo sapiens
created
[InstanceEdit:9756407] May, Bruce, 2021-10-14
dbId
9756422
displayName
CDH1 gene [nucleoplasm]
endCoordinate
-1
inDisease
false
inferredTo
[GenomeEncodedEntity:R-MMU-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Mus musculus
[GenomeEncodedEntity:R-RNO-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Rattus norvegicus
[GenomeEncodedEntity:R-CFA-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Canis familiaris
[GenomeEncodedEntity:R-BTA-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Bos taurus
[GenomeEncodedEntity:R-SSC-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Sus scrofa
[GenomeEncodedEntity:R-DRE-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Danio rerio
[GenomeEncodedEntity:R-XTR-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Xenopus tropicalis
[GenomeEncodedEntity:R-GGA-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Gallus gallus
[GenomeEncodedEntity:R-DME-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Drosophila melanogaster
[GenomeEncodedEntity:R-CEL-9756422] Ghost homologue of CDH1 gene [nucleoplasm] - Caenorhabditis elegans
maxDepth
1
name
CDH1 gene
referenceEntity
[ReferenceDNASequence:ensembl:ENSG00000039068] ENSEMBL:ENSG00000039068 CDH1
referenceType
ReferenceDNASequence
schemaClass
EntityWithAccessionedSequence
species
[Species:48887] Homo sapiens
stId
R-HSA-9756422
startCoordinate
1
Referrals
(hasComponent)
[Complex:R-HSA-9825718] p-S742 TBX3:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9926384] MITF-M dimer:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9815640] TWIST1:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931356] TCF12:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931128] KDM1A:ZNF217:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9815907] PRC2 (EZH2) Core:Nucleosome:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9815909] PRC2 (EZH2) Core:H3K27me3-Nucleosome:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931099] TWIST2:CDH1 gene [nucleoplasm]
[Complex:R-NUL-9794436] Snai1:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9756435] SNAI1:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931220] WT1 homodimer:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931372] TCF3:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793459] ZEB1:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9815874] DNTTIP1:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9794242] RB1:TFAP2A homodimer:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793360] SP1:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793709] FOXJ2:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793550] KLF4:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793552] ZEB2:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793593] FOXA2:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931142] FOXQ1:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793776] ARID1A:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9793539] KLF9:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9796473] SNAI2:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931737] CTBP1,CTBP2:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9816005] ZBTB33:CDH1 gene [nucleoplasm]
[Complex:R-HSA-9931501] PKM:TGIF2:CDH1 gene [nucleoplasm]
(input)
[BlackBoxEvent:R-HSA-9825774] SNAI2 and TBX3 repress CDH1 gene expression during melanocyte development
[Reaction:R-HSA-9825794] p-S742 TBX3 binds CDH1 promoter
[BlackBoxEvent:R-HSA-9926527] MITF-M-dependent CDH1 gene expression
[Reaction:R-HSA-9926495] MITF-M binds CDH1 gene
[BlackBoxEvent:R-HSA-9823995] Expression of E-cadherin (CDH1) in definitive endoderm
[Reaction:R-HSA-9756414] SNAI1 binds the CDH1 gene
[Reaction:R-HSA-9767922] TCF12 binds CDH1 gene promoter
[Reaction:R-HSA-9767700] WT1 binds CDH1 gene promoter
[Reaction:R-HSA-9765015] TWIST1 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9765049] TWIST1 represses CDH1 gene transcription
[BlackBoxEvent:R-HSA-9767924] TCF12 represses CDH1 gene transcription
[Reaction:R-HSA-9768067] ZNF217 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9768071] ZNF217 represses CDH1 gene transcription
[Reaction:R-HSA-9765313] ZEB2 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9765293] ZEB2 represses CDH1 gene transcription
[Reaction:R-HSA-9764930] PRC2 (EZH2) core complex binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9764934] PRC2 (EZH2) mediates repression of CDH1 gene transcription
[Reaction:R-HSA-9765169] TWIST2 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9765175] TWIST2 represses CDH1 gene transcription
[BlackBoxEvent:R-NUL-9794433] Snai1 represses CDH1 gene transcription
[BlackBoxEvent:R-HSA-9764752] SNAI1 represses CDH1 transcription
[BlackBoxEvent:R-HSA-9767706] WT1 represses CDH1 gene transcription
[Reaction:R-HSA-9765742] TCF3 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9765756] TCF3 represses CDH1 gene transcription
[Reaction:R-HSA-9764741] ZEB1 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9764778] ZEB1 represses CDH1 gene transcription
[Reaction:R-HSA-9764811] DNTTIP1 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9764827] DNTTIP1 and KDM1A repress CDH1 gene transcription
[Reaction:R-HSA-9766062] PKM and TGIF2 bind CDH1 gene promoter
[BlackBoxEvent:R-HSA-9768293] RB1 and TFAP2A stimulate CDH1 gene transcription
[Reaction:R-HSA-9768288] RB1 and TFAP2A bind CDH1 gene promoter
[BlackBoxEvent:R-HSA-9764800] SP1 stimulates CDH1 gene transcription
[Reaction:R-HSA-9764791] SP1 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9765539] FOXJ2 stimulates CDH1 gene transcription
[Reaction:R-HSA-9765542] FOXJ2 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9765330] KLF4 stimulates CDH1 gene transcription
[Reaction:R-HSA-9765326] KLF4 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9765372] FOXA2 stimulates CDH1 gene transcription
[Reaction:R-HSA-9765371] FOXA2 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9768079] FOXQ1 represses CDH1 gene transcription
[Reaction:R-HSA-9768082] FOXQ1 bind CDH1 gene promoter
[BlackBoxEvent:R-HSA-9766286] ARID1A and SWI/SNF complex stimulate CDH1 gene transcription
[Reaction:R-HSA-9766293] ARID1A binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9764863] KLF9 stimulates CDH1 gene transcription
[Reaction:R-HSA-9764866] KLF9 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9768484] SNAI2 represses CDH1 gene transcription
[Reaction:R-HSA-9768533] SNAI2 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9768511] CTBP1,CTBP2 represses CDH1 gene transcription
[Reaction:R-HSA-9768477] CTBP1,CTBP2 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9767779] ZBTB33 represses CDH1 gene transcription
[Reaction:R-HSA-9767787] ZBTB33 binds CDH1 gene promoter
[BlackBoxEvent:R-HSA-9766065] PKM and TGIF2 repress CDH1 gene transcription
© 2026
Reactome
This website requires cookies and the limited processing of your personal data in order to function. By using the site you are agreeing to this as outlined in our
Privacy Notice
.
I agree, dismiss this banner
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text