Reactome | KLF4 stimulates CDH1 gene transcription

Schema > BlackBoxEvent > Entries

KLF4 stimulates CDH1 gene transcription Show undefined attributes

authored	[InstanceEdit:9765328] Orlic-Milacic, Marija, 2022-02-15
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:9765328] Orlic-Milacic, Marija, 2022-02-15
dbId	9765330
displayName	KLF4 stimulates CDH1 gene transcription
edited	[InstanceEdit:9930641] Orlic-Milacic, Marija, 2024-12-04
eventOf	[Pathway:R-HSA-9764790] Positive Regulation of CDH1 Gene Transcription - Homo sapiens
followingEvent	[Reaction:R-HSA-9768643] miR-10b binds CDH1 mRNA - Homo sapiens [Reaction:R-HSA-9768616] miR-9 binds CDH1 mRNA - Homo sapiens [BlackBoxEvent:R-HSA-9768618] miR-10b inhibits CDH1 mRNA translation - Homo sapiens [BlackBoxEvent:R-HSA-9768614] miR-9 inhibits CDH1 mRNA translation - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9756422] CDH1 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9765331] Interplay between KLF4 and ZEB2/SIP1 in the regulation of E-cadherin expression [LiteratureReference:9768178] Kruppel-like factor 4 inhibits epithelial-to-mesenchymal transition through regulation of E-cadherin gene expression
maxDepth	1
modified	[InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
name	KLF4 stimulates CDH1 gene transcription
output	[EntityWithAccessionedSequence:R-HSA-9793365] CDH1 mRNA [cytosol]
precedingEvent	[Reaction:R-HSA-9765326] KLF4 binds CDH1 gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:9793578] Positive gene expression regulation by 'KLF4:CDH1 gene [nucleoplasm]'
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-9765330
summation	[Summation:9793547] The transcription factor Kruppel-like factor 4 (KLF4) direct...

Referrals

(hasEvent)	[Pathway:R-HSA-9764790] Positive Regulation of CDH1 Gene Transcription
(precedingEvent)	[BlackBoxEvent:R-HSA-9768618] miR-10b inhibits CDH1 mRNA translation [Reaction:R-HSA-9768643] miR-10b binds CDH1 mRNA [Reaction:R-HSA-9768616] miR-9 binds CDH1 mRNA [BlackBoxEvent:R-HSA-9768614] miR-9 inhibits CDH1 mRNA translation

Cite Us!