Reactome | TCF3 binds CDH1 gene promoter

Schema > Reaction > Entries

authored	[InstanceEdit:9765752] Orlic-Milacic, Marija, 2022-02-16
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:9765752] Orlic-Milacic, Marija, 2022-02-16
dbId	9765742
displayName	TCF3 binds CDH1 gene promoter
edited	[InstanceEdit:9931380] Orlic-Milacic, Marija, 2024-12-11
eventOf	[Pathway:R-HSA-9764725] Negative Regulation of CDH1 Gene Transcription - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9765756] TCF3 represses CDH1 gene transcription - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-9756422] CDH1 gene [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-3209896] TCF3 [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:9765763] PAK5-mediated E47 phosphorylation promotes epithelial-mesenchymal transition and metastasis of colon cancer [LiteratureReference:9931369] Loss of ID3 drives papillary thyroid cancer metastasis by targeting E47-mediated epithelial to mesenchymal transition
maxDepth	1
modified	[InstanceEdit:9949646] Orlic-Milacic, Marija, 2025-05-23
name	TCF3 binds CDH1 gene promoter
output	[Complex:R-HSA-9931372] TCF3:CDH1 gene [nucleoplasm]
releaseDate	2025-06-18
reviewStatus	[ReviewStatus:9821383] three stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-9765742
summation	[Summation:9931373] TCF3 (also known as E47), was shown to bind to both mouse (P...

(hasEvent)	[Pathway:R-HSA-9764725] Negative Regulation of CDH1 Gene Transcription
(precedingEvent)	[BlackBoxEvent:R-HSA-9765756] TCF3 represses CDH1 gene transcription

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