Shamith Samarajiwa

Cancer Research UK, Cambridge Institute, University of Cambridge
Reviewed Pathways (6/6)
Date Identifier Pathway Reference
2013-09-03 R-HSA-2559584 Formation of Senescence-Associated Heterochromatin Foci (SAHF) BibTex
2013-09-03 R-HSA-2559585 Oncogene Induced Senescence BibTex
2013-09-03 R-HSA-2559586 DNA Damage/Telomere Stress Induced Senescence BibTex
2013-09-03 R-HSA-2559582 Senescence-Associated Secretory Phenotype (SASP) BibTex
2013-09-03 R-HSA-2559580 Oxidative Stress Induced Senescence BibTex
2013-09-03 R-HSA-2559583 Cellular Senescence BibTex
Reviewed Reactions (15/79)
Date Identifier Reaction Reference
2013-09-03 R-HSA-5693540 MRN activates ATM BibTex
2013-09-03 R-HSA-5693612 MRN complex bound to DNA ends recruits ATM BibTex
2013-09-03 R-HSA-3785768 MRN complex binds DNA double strand breaks BibTex
2013-09-03 R-HSA-3785704 DSB inducing agents induce double strand DNA breaks BibTex
2013-09-03 R-HSA-5682026 MRN bound to shortened telomeres activates ATM BibTex
2013-09-03 R-HSA-5682018 MRN complex bound to shortened telomeres recruits ATM BibTex
2013-09-03 R-HSA-5682020 MRN complex binds shortened telomeres BibTex
2013-09-03 R-HSA-3785711 Telomere shortening during replicative exhaustion BibTex
2013-09-03 R-HSA-6804879 MDM2 ubiquitinates TP53 BibTex
2013-09-03 R-HSA-3228469 MAP3K5 phosphorylates MKK3 and MKK6 BibTex
2013-09-03 R-HSA-3225851 ROS oxidize thioredoxin and activate MAP3K5 BibTex
2013-09-03 R-HSA-3223236 RAS signaling and prolonged interferon-beta stimulation promote generation of reactive oxygen species (ROS) BibTex
2013-09-03 R-HSA-6803801 TP53 in complex with ZNF385A binds the CDKN1A promoter BibTex
2013-09-03 R-HSA-4647613 Transcriptional activation of CDKN1A by TP53 is inhibited by EP400 BibTex
2013-09-03 R-HSA-3786258 TP53 binds the CDKN1A promoter BibTex
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