26105537 |
Forging a signature of in vivo senescence
Sharpless, NE,
Sherr, CJ
|
Nat. Rev. Cancer |
2015 |
12839923 |
Smad3 regulates senescence and malignant conversion in a mouse multistage skin carcinogenesis model
Vijayachandra, K,
Lee, J,
Glick, AB
|
Cancer Res. |
2003 |
10733595 |
Cellular response to oncogenic ras involves induction of the Cdk4 and Cdk6 inhibitor p15(INK4b)
Malumbres, M,
Pérez De Castro, I,
Hernández, MI,
Jimenez, M,
Corral, T,
Pellicer, A
|
Mol. Cell. Biol. |
2000 |
9824166 |
Mdm2 association with p53 targets its ubiquitination
Fuchs, SY,
Adler, V,
Buschmann, T,
Wu, X,
Ronai, Z
|
Oncogene |
1998 |
11883935 |
Transcriptional regulation of the human tumor suppressor p14(ARF) by E2F1, E2F2, E2F3, and Sp1-like factors
Parisi, T,
Pollice, A,
Di Cristofano, A,
Calabrò, V,
La Mantia, G
|
Biochem. Biophys. Res. Commun. |
2002 |
10722742 |
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53
Fang, S,
Jensen, JP,
Ludwig, RL,
Vousden, KH,
Weissman, AM
|
J. Biol. Chem. |
2000 |
14729966 |
ERF nuclear shuttling, a continuous monitor of Erk activity that links it to cell cycle progression
Le Gallic, L,
Virgilio, L,
Cohen, P,
Biteau, B,
Mavrothalassitis, G
|
Mol. Cell. Biol. |
2004 |
9529249 |
ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
Zhang, Y,
Xiong, Y,
Yarbrough, WG
|
Cell |
1998 |
8552081 |
Ras-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2
Yang, BS,
Hauser, CA,
Henkel, G,
Colman, MS,
Van Beveren, C,
Stacey, KJ,
Hume, DA,
Maki, RA,
Ostrowski, MC
|
Mol. Cell. Biol. |
1996 |
15572696 |
Ras/mitogen-activated protein kinase signaling activates Ets-1 and Ets-2 by CBP/p300 recruitment
Foulds, CE,
Nelson, ML,
Blaszczak, AG,
Graves, BJ
|
Mol. Cell. Biol. |
2004 |
27812880 |
Detection of Oncogene-Induced Senescence In Vivo
Baek, KH,
Ryeom, S
|
Methods Mol. Biol. |
2017 |
8319905 |
The p53-mdm-2 autoregulatory feedback loop
Wu, X,
Bayle, JH,
Olson, D,
Levine, AJ
|
Genes Dev. |
1993 |
9704925 |
Involvement of the Ink4 proteins p16 and p15 in T-lymphocyte senescence
Erickson, S,
Sangfelt, O,
Heyman, M,
Castro, J,
Einhorn, S,
Grandér, D
|
Oncogene |
1998 |
8521522 |
Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest
Quelle, DE,
Zindy, F,
Ashmun, RA,
Sherr, CJ
|
Cell |
1995 |
8259215 |
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
Serrano, M,
Hannon, GJ,
Beach, D
|
Nature |
1993 |
22336108 |
Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development
To, KH,
Pajovic, S,
Gallie, BL,
Thériault, BL
|
BMC Cancer |
2012 |
11782450 |
An ERK2 docking site in the Pointed domain distinguishes a subset of ETS transcription factors
Seidel, JJ,
Graves, BJ
|
Genes Dev. |
2002 |
20583212 |
Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth
Senturk, S,
Mumcuoglu, M,
Gursoy-Yuzugullu, O,
Cingoz, B,
Akcali, KC,
Ozturk, M
|
Hepatology |
2010 |
11234019 |
Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence
Ohtani, N,
Zebedee, Z,
Huot, TJ,
Stinson, JA,
Sugimoto, M,
Ohashi, Y,
Sharrocks, AD,
Peters, G,
Hara, E
|
Nature |
2001 |
7588608 |
ERF: an ETS domain protein with strong transcriptional repressor activity, can suppress ets-associated tumorigenesis and is regulated by phosphorylation during cell cycle and mitogenic stimulation
Sgouras, DN,
Athanasiou, MA,
Beal, GJ,
Fisher, RJ,
Blair, DG,
Mavrothalassitis, GJ
|
EMBO J. |
1995 |
20534573 |
Ras signaling requires dynamic properties of Ets1 for phosphorylation-enhanced binding to coactivator CBP
Nelson, ML,
Kang, HS,
Lee, GM,
Blaszczak, AG,
Lau, DK,
McIntosh, LP,
Graves, BJ
|
Proc. Natl. Acad. Sci. U.S.A. |
2010 |
18365017 |
p16(INK4a) translation suppressed by miR-24
Lal, A,
Kim, HH,
Abdelmohsen, K,
Kuwano, Y,
Pullmann, R,
Srikantan, S,
Subrahmanyam, R,
Martindale, JL,
Yang, X,
Ahmed, F,
Navarro, F,
Dykxhoorn, D,
Lieberman, J,
Gorospe, M
|
PLoS ONE |
2008 |