Reactome | PEX7 [cytosol]

PEX7 [cytosol]

Stable Identifier

R-HSA-9033107

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Peroxisomal targeting signal 2 receptor, PEX7_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O00628 PEX7

Gene Names

PEX7, PTS2R

Chain

chain:1-323

Reference Genes

BioGPS Gene:5191 PEX7

COSMIC (genes):PEX7 PEX7

CTD Gene:5191 PEX7

dbSNP Gene:5191 PEX7

ENSEMBL:ENSG00000112357 PEX7

HGNC:8860 PEX7

KEGG Gene (Homo sapiens):5191 PEX7

Monarch:5191 PEX7

NCBI Gene:5191 PEX7

OMIM:601757 PEX7

UCSC:O00628 PEX7

Reference Transcript

RefSeq:NM_000288.3 PEX7

Other Identifiers

0007040471

11722338_at

17012888

205420_at

211033_s_at

2927254

2927256

2927257

2927258

2927259

2927261

2927262

2927268

2927269

2927270

2927271

2927272

2927273

2927275

2927279

2927280

2927281

40654_at

5191

80931_at

8122242

A_14_P101723

A_23_P93543

A_33_P3412095

GE59524

GO:0001764

GO:0001958

GO:0003674

GO:0005053

GO:0005515

GO:0005575

GO:0005622

GO:0005737

GO:0005777

GO:0005778

GO:0005782

GO:0005829

GO:0006605

GO:0006625

GO:0006629

GO:0006635

GO:0006810

GO:0007031

GO:0008150

GO:0008611

GO:0009056

GO:0009058

GO:0015031

GO:0016558

GO:0019899

GO:0030154

GO:0040011

GO:0042803

GO:0043226

GO:0044281

GO:0048856

GO:0048870

GO:0055085

ILMN_1729650

PH_hs_0004617

TC06001019.hg

U88871_at

g13623327_3p_s_at

g4505730_3p_at

Participant Of

output

PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol

input

PEX7 binds cargo proteins containing PTS2

hasComponent

Other forms of this molecule

PEX7 [peroxisomal membrane]

Inferred To

pex7 [cytosol] (Danio rerio)

pex7 [cytosol] (Dictyostelium discoideum)

pex7 [cytosol] (Schizosaccharomyces pombe)

PEX7 [cytosol] (Bos taurus)

PEX7 [cytosol] (Canis familiaris)

PEX7 [cytosol] (Gallus gallus)

PEX7 [cytosol] (Saccharomyces cerevisiae)

PEX7 [cytosol] (Sus scrofa)

Pex7 [cytosol] (Drosophila melanogaster)

Pex7 [cytosol] (Mus musculus)

Pex7 [cytosol] (Rattus norvegicus)

Ghost homologue of PEX7 [cytosol] (Caenorhabditis elegans)

Ghost homologue of PEX7 [cytosol] (Xenopus tropicalis)

Cross References

RefSeq

NP_000279.1

OpenTargets

ENSG00000112357

GeneCards

O00628

HPA

ENSG00000112357-PEX7

Ensembl

ENSP00000441004, ENSP00000315680, ENST00000318471, ENST00000541292, ENSG00000112357

PRO

O00628

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O75925 PIAS1	1	PIAS1 [nucleoplasm] (R-HSA-877307)	0.556	3