Reactome | PDCL [cytosol]

PDCL [cytosol]

Stable Identifier

R-HSA-6813727

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Phosducin-like protein, PHLP, PhLP1, PHLOP1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13371 PDCL

Gene Names

PDCL, PHLOP1, PhLP1

Chain

initiator methionine:, chain:2-301

Reference Genes

BioGPS Gene:5082 PDCL

COSMIC (genes):PDCL PDCL

CTD Gene:5082 PDCL

dbSNP Gene:5082 PDCL

ENSEMBL:ENSG00000136940 PDCL

ENSEMBL_homo_sapiens_GENE:ENSG00000136940.14 PDCL

HGNC:8770 PDCL

KEGG Gene (Homo sapiens):5082 PDCL

Monarch:5082 PDCL

NCBI Gene:5082 PDCL

OMIM:604421 PDCL

UCSC:Q13371 PDCL

Reference Transcript

RefSeq:NM_005388.4 PDCL

Other Identifiers

11723992_at

11756349_a_at

1559161_PM_at

1559161_at

17098127

204448_PM_s_at

204448_s_at

204449_3p_at

204449_PM_at

204449_at

239324_PM_at

239324_at

3224344

3224345

3224346

3224347

3224348

3224349

3224352

3224354

3224355

41019_at

42767_r_at

5082

61020_at

8163964

82179_at

A_23_P216949

A_23_P349882

A_33_P3405360

GE54244

GO:0005515

GO:0005737

GO:0005829

GO:0005929

GO:0007165

GO:0007601

GO:0008277

GO:0023052

GO:0030030

GO:0042995

GO:0043226

GO:0045880

GO:0050877

GO:0050896

GO:0065003

GO:1902605

HMNXSV003057709

Hs.271749.0.A1_3p_at

Hs2.239116.1.A1_3p_at

ILMN_1694041

PH_hs_0013992

TC09001562.hg

TC09001563.hg

TC09002780.hg

g4104074_3p_a_at

g9943841_3p_s_at

p26509

p28696

Participates

as an input of

CK2 phosphorylates PDCL (Homo sapiens)

Other forms of this molecule

p-S18,S19,S20,S25-PDCL [cytosol]

Inferred To

mau-8 [cytosol] (Caenorhabditis elegans)

pdcl [cytosol] (Xenopus tropicalis)

PDCL [cytosol] (Bos taurus)

PDCL [cytosol] (Canis familiaris)

PDCL [cytosol] (Drosophila melanogaster)

PDCL [cytosol] (Gallus gallus)

PDCL [cytosol] (Sus scrofa)

Pdcl [cytosol] (Mus musculus)

Pdcl [cytosol] (Rattus norvegicus)

Cross References

RefSeq

NP_005379.3

OpenTargets

ENSG00000136940

GeneCards

Q13371

HPA

ENSG00000136940-PDCL

Ensembl

ENSG00000136940, ENSP00000259467, ENST00000259467

PRO

Q13371

Pharos - Targets

Q13371

HMDB Protein

HMDBP08504

PDB

8SHT, 8SHO, 8SHA, 8SHP, 8SFF, 8SGC, 8SHF, 8SH9, 8SHQ, 8SHL, 8SG8, 8SHG

Interactors (22)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62195 PSMC5	2	PSMC5 [nucleoplasm] (R-HSA-174312) PSMC5 [cytosol] (R-HSA-68780)	0.919	16
UniProt:P49368 CCT3	1	CCT3 [cytosol] (R-HSA-390463)	0.742	9
UniProt:Q99832 CCT7	1	CCT7 [cytosol] (R-HSA-390451)	0.643	4
UniProt:Q9Y3B7 MRPL11	1	MRPL11 [mitochondrial inner membrane] (R-HSA-5368251)	0.556	3
UniProt:Q86V38 Q86V38			0.556	3
UniProt:Q92876 KLK6			0.556	3
UniProt:P63215 GNG3	1	GNG3 [plasma membrane] (R-HSA-164376)	0.527	2
UniProt:P62873 GNB1	5	GNB1 [photoreceptor disc membrane] (R-HSA-55373) Unfolded GNB1 [cytosol] (R-HSA-6814200) Partially folded GNB1 [cytosol] (R-HSA-8850526) GNB1 [plasma membrane] (R-HSA-164347) GNB1 [cytosol] (R-HSA-6814412)	0.527	3
UniProt:Q9NRH3 TUBG2	1	TUBG2 [cytosol] (R-HSA-379272)	0.527	2
UniProt:P78371 CCT2	3	CCT2 [extracellular region] (R-HSA-6806220) CCT2 [azurophil granule lumen] (R-HSA-6799356) CCT2 [cytosol] (R-HSA-390464)	0.527	4
UniProt:Q14990 ODFP1			0.527	2
UniProt:P57775 FBXW4	1	FBXW4 [cytosol] (R-HSA-391305)	0.527	2
UniProt:Q9H2J4 PDCL3			0.527	3
UniProt:Q8IYD2 KLD8A			0.527	2
UniProt:Q17RF5 ODAPH			0.527	3
UniProt:Q14318 FKBP8	2	PolyUb-FKBP8 [mitochondrial outer membrane] (R-HSA-6783001) FKBP8 [mitochondrial outer membrane] (R-HSA-5696928)	0.527	2
UniProt:Q9Y3L5 RAP2C	2	RAP2C [plasma membrane] (R-HSA-6804983) RAP2C [tertiary granule membrane] (R-HSA-6804975)	0.527	2
UniProt:P48643 CCT5	1	CCT5 [cytosol] (R-HSA-390447)	0.527	4
UniProt:P50150 GNG4	1	GNG4 [plasma membrane] (R-HSA-164350)	0.527	2
UniProt:P62879 GNB2	4	GNB2 [cytosol] (R-HSA-6814421) Partially folded GNB2 [cytosol] (R-HSA-8850536) Unfolded GNB2 [cytosol] (R-HSA-6814202) GNB2 [plasma membrane] (R-HSA-164335)	0.527	3
UniProt:O00628 PEX7	2	PEX7 [peroxisomal membrane] (R-HSA-9033493) PEX7 [cytosol] (R-HSA-9033107)	0.527	2
UniProt:P63211 GNGT1	3	S-farn-GNGT1 [photoreceptor disc membrane] (R-HSA-2530520) GNGT1 [photoreceptor disc membrane] (R-HSA-55393) GNGT1 [plasma membrane] (R-HSA-167428)	0.499	2

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