Reactome | PFDN5 [cytosol]

PFDN5 [cytosol]

Stable Identifier

R-HSA-379548

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q99471 PFDN5

Gene Names

PFDN5, MM1, PFD5

Chain

initiator methionine:, chain:2-154

Reference Genes

BioGPS Gene:5204 PFDN5

COSMIC (genes):PFDN5 PFDN5

CTD Gene:5204 PFDN5

dbSNP Gene:5204 PFDN5

ENSEMBL:ENSG00000123349 PFDN5

HGNC:8869 PFDN5

Monarch:5204 PFDN5

NCBI Gene:5204 PFDN5

OMIM:604899 PFDN5

UCSC:Q99471 PFDN5

Reference Transcript

Other Identifiers

11716608_a_at

11750089_x_at

11757641_x_at

16751750

1817_at

207132_PM_x_at

207132_x_at

210908_PM_s_at

210908_s_at

3322970

3415916

3415917

3415918

3415919

3415920

3415921

3415922

3415923

3415924

3415925

3415926

3415927

3415928

3415929

3415930

3415931

3415932

3415933

3415934

3415935

3415936

3415938

3415939

3415940

3415941

3415942

3415943

3415944

5204

7955768

A_14_P104863

A_23_P128192

A_24_P181120

D89667_at

GO:0001540

GO:0003714

GO:0005515

GO:0005634

GO:0005737

GO:0005829

GO:0005856

GO:0006355

GO:0006457

GO:0016272

GO:0043226

GO:0045111

GO:0045892

GO:0048856

GO:0051082

GO:0060041

GO:0060090

GO:0061077

GO:0065003

GO:0090090

GO:0140110

GO:1905907

GO:1990113

GO:1990114

GO:1990115

HMNXSV003037287

ILMN_1755536

ILMN_2356284

PH_hs_0015003

TC12000435.hg

g4505742_3p_a_at

Participates

as a component of

Prefoldin [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSP00000517421, ENSP00000243040, ENSP00000447942, ENSP00000334188, ENSP00000266964, ENST00000551018, ENST00000708936, ENST00000351500, ENST00000708937, ENST00000708922, ENST00000334478, ENST00000708930, ENSP00000517425, ENST00000243040, ENSP00000517429, ENSP00000517428

OpenTargets

ENSG00000123349

HPA

ENSG00000123349-PFDN5

PRO

Q99471

Pharos - Targets

Q99471

GlyGen

Q99471

PDB

7WU7, 6NR9, 6NR8, 6NRD, 6NRC, 6NRB

Interactors (19)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61289 PSME3	1	PSME3 [cytosol] (R-HSA-68816)	0.718	6
UniProt:Q13164 MAPK7	4	p-T218,Y221-MAPK7 [nucleoplasm] (R-HSA-198738) p-T218,Y221-MAPK7 [cytosol] (R-HSA-198721) MAPK7 [cytosol] (R-HSA-198754) MAPK7 [nucleoplasm] (R-HSA-199961)	0.643	4
UniProt:Q13547 HDAC1	2	HDAC1 [nucleoplasm] (R-HSA-205021) monoSUMO1-K444,K476-HDAC1 [nucleoplasm] (R-HSA-4616030)	0.643	4
UniProt:P41182 BCL6	1	BCL6 [nucleoplasm] (R-HSA-5223066)	0.556	3
UniProt:Q99633 PRPF18	1	PRPF18 [nucleoplasm] (R-HSA-5688093)	0.556	3
UniProt:Q9BZI1 IRX2	1	IRX2 [nucleoplasm] (R-HSA-9832184)	0.556	3
UniProt:O60341 KDM1A	1	KDM1A [nucleoplasm] (R-HSA-996769)	0.556	3
UniProt:O76003 GLRX3	1	GLRX3 [cytosol] (R-HSA-5691202)	0.556	3
UniProt:P28070 PSMB4	4	PSMB4 [cytosol] (R-HSA-68750) PSMB4 [nucleoplasm] (R-HSA-174343) pro-PSMB4 [cytosol] (R-HSA-9908138) PSMB4(1-45) [cytosol] (R-HSA-9908122)	0.556	3
UniProt:Q13163 MAP2K5	1	MAP2K5 [cytosol] (R-HSA-198722)	0.556	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:O14503 BHLHE40	1	BHLHE40 [nucleoplasm] (R-HSA-879741)	0.556	3
UniProt:Q8WXB1 METTL21A	1	METTL21A [nucleoplasm] (R-HSA-8876682)	0.556	3
UniProt:Q8IVS8 GLYCTK	1	GLYCTK [cytosol] (R-HSA-6799244)	0.556	3
UniProt:O95863 SNAI1	1	SNAI1 [nucleoplasm] (R-HSA-2980903)	0.556	3
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.556	3
UniProt:O15119 TBX3	2	TBX3 [nucleoplasm] (R-HSA-9825678) p-S742 TBX3 [nucleoplasm] (R-HSA-9825680)	0.556	3
UniProt:P31273 HOXC8	1	HOXC8 [nucleoplasm] (R-HSA-3222311)	0.556	3
UniProt:Q92466 DDB2	3	DDB2 [nucleoplasm] (R-HSA-53491) PAR-DDB2 [nucleoplasm] (R-HSA-5696654) PolyUb-DDB2 [nucleoplasm] (R-HSA-6783035)	0.527	2

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