Reactome | PVRL3 [plasma membrane]

PVRL3 [plasma membrane]

Stable Identifier

R-HSA-449762

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Nectin-3, Poliovirus receptor-related protein 3, PVRL3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9NQS3 NECTIN3

Gene Names

NECTIN3, PRR3, PVRL3

Chain

signal peptide:1-57, chain:58-549

Reference Genes

BioGPS Gene:25945 NECTIN3

COSMIC (genes):NECTIN3 NECTIN3

CTD Gene:25945 NECTIN3

dbSNP Gene:25945 NECTIN3

ENSEMBL:ENSG00000177707.11 NECTIN3

HGNC:17664 NECTIN3

KEGG Gene (Homo sapiens):25945 NECTIN3

Monarch:25945 NECTIN3

NCBI Gene:25945 NECTIN3

OMIM:607147 NECTIN3

UCSC:Q9NQS3 NECTIN3

Reference Transcript

Other Identifiers

11727125_a_at

11758970_a_at

213325_PM_at

213325_at

25945

2635646

2635647

2635648

2635649

2635650

2635658

2635659

2635662

2635663

2635664

2635665

2635666

2635668

2635669

2635670

2635671

2635672

2635673

2635674

2635675

2635676

2635677

2635678

2635679

2635680

2635686

2635688

2635700

2635701

2635702

34202_at

52424_r_at

62947_at

8081548

86478_at

A_14_P108380

A_14_P114827

A_14_P133366

A_21_P0014108

A_23_P401547

A_23_P80759

A_23_P80763

A_24_P225862

GE82009

GO:0002089

GO:0005515

GO:0005886

GO:0005911

GO:0005912

GO:0007155

GO:0007156

GO:0007157

GO:0007286

GO:0009566

GO:0016020

GO:0022414

GO:0030154

GO:0042802

GO:0042803

GO:0043226

GO:0043296

GO:0044291

GO:0045202

GO:0045211

GO:0048856

GO:0050839

GO:0060042

GO:0061951

GO:0072659

GO:0098609

GO:0098686

GO:0098839

GO:1902414

HMNXSV003002470

HMNXSV003046933

Hs.21201.0.S2_3p_at

ILMN_1727633

ILMN_2188521

PH_hs_0025521

PH_hs_0035997

Participates

as a member of

Nectin [plasma membrane] (Homo sapiens)

as a component of

as an input of

Inferred To

NECTIN3 [plasma membrane] (Bos taurus)

NECTIN3 [plasma membrane] (Gallus gallus)

NECTIN3 [plasma membrane] (Sus scrofa)

nectin3 [plasma membrane] (Danio rerio)

nectin3 [plasma membrane] (Xenopus tropicalis)

PVRL3 [plasma membrane] (Canis familiaris)

Nectin3 [plasma membrane] (Mus musculus)

Nectin3 [plasma membrane] (Rattus norvegicus)

Cross References

RefSeq

NP_001230215.1, NP_001230217.1, NP_056295.1

OpenTargets

ENSG00000177707

GeneCards

Q9NQS3

HPA

ENSG00000177707-NECTIN3

Ensembl

ENST00000485303, ENSG00000177707, ENST00000493615, ENSP00000418070, ENST00000319792, ENSP00000321514, ENSP00000420579

PRO

Q9NQS3

Pharos - Targets

Q9NQS3

Orphanet

26409

PDB

4FOM

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q7Z3S9 NT2NA			0.666	4
UniProt:P55196 AFDN			0.646	4
UniProt:Q92692 NECTIN2	1	PVRL2 [plasma membrane] (R-HSA-419006)	0.609	3
UniProt:Q15223 NECTIN1	1	PVRL1 [plasma membrane] (R-HSA-3008842)	0.589	3
IntAct:EBI-10171679 386682			0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:P60411 KRTAP10-9	1	KRTAP10-9 [cytosol] (R-HSA-6810277)	0.556	3
UniProt:Q9BYR5 KRTAP4-2	1	KRTAP4-2 [cytosol] (R-HSA-6809948)	0.556	3
UniProt:O76081 RGS20	1	RGS20 [plasma membrane] (R-HSA-921136)	0.556	3
UniProt:P21333-2 FLNA			0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3