Reactome | PVRL3 [plasma membrane]

PVRL3 [plasma membrane]

Stable Identifier

R-HSA-449762

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Nectin-3, Poliovirus receptor-related protein 3, PVRL3_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9NQS3 NECTIN3

Gene Names

NECTIN3, PRR3, PVRL3

Chain

signal peptide:1-57, chain:58-549

Reference Genes

BioGPS Gene:25945 NECTIN3

COSMIC (genes):NECTIN3 NECTIN3

COSMIC (genes):PRR3 NECTIN3

CTD Gene:25945 NECTIN3

dbSNP Gene:25945 NECTIN3

ENSEMBL:ENSG00000177707 NECTIN3

HGNC:17664 NECTIN3

KEGG:hsa:25945 NECTIN3

Monarch:25945 NECTIN3

NCBI Gene:25945 NECTIN3

OMIM:607147 NECTIN3

UCSC:Q9NQS3 NECTIN3

Reference Transcript

Participates

as a member of

Nectin [plasma membrane] (Homo sapiens)

as a component of

as an input of

Inferred To

NECTIN3 [plasma membrane] (Bos taurus)

NECTIN3 [plasma membrane] (Canis familiaris)

NECTIN3 [plasma membrane] (Gallus gallus)

NECTIN3 [plasma membrane] (Sus scrofa)

nectin3 [plasma membrane] (Danio rerio)

igcm-3 [plasma membrane] (Caenorhabditis elegans)

Fas3 [plasma membrane] (Drosophila melanogaster)

Nectin3 [plasma membrane] (Mus musculus)

Nectin3 [plasma membrane] (Rattus norvegicus)

Cross References

ENSEMBL

ENST00000485303, ENSP00000321514, ENSP00000418070, ENSP00000420579, ENST00000493615, ENST00000319792, ENSG00000177707

OpenTargets

ENSG00000177707

GeneCards

NECTIN3

HPA

ENSG00000177707-NECTIN3

PRO

Q9NQS3

Pharos - Targets

Q9NQS3

GlyGen

Q9NQS3

PDB

4FOM

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q92692 NECTIN2	1	PVRL2 [plasma membrane] (R-HSA-419006)	0.702	4
UniProt:Q15223 NECTIN1	1	PVRL1 [plasma membrane] (R-HSA-3008842)	0.688	4
UniProt:Q7Z3S9 NOTCH2NLA	3	NOTCH2NLA [extracellular region] (R-HSA-9908935) NOTCH2NLA(1-?) [extracellular region] (R-HSA-9911493) NOTCH2NLA(?-236) [extracellular region] (R-HSA-9911490)	0.666	4
UniProt:P55196 AFDN			0.646	4
IntAct:EBI-10171679 386682			0.556	3
UniProt:P60410 KRTAP10-8	1	KRTAP10-8 [cytosol] (R-HSA-6810301)	0.556	3
UniProt:Q9BYR5 KRTAP4-2	1	KRTAP4-2 [cytosol] (R-HSA-6809948)	0.556	3
UniProt:P60411 KRTAP10-9	1	KRTAP10-9 [cytosol] (R-HSA-6810277)	0.556	3
UniProt:O76081 RGS20	1	RGS20 [plasma membrane] (R-HSA-921136)	0.556	3
UniProt:P21333-2 FLNA			0.556	3
UniProt:P60409 KRTAP10-7	1	KRTAP10-7 [cytosol] (R-HSA-6810279)	0.556	3

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