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ALDH3B1 [plasma membrane]
Stable Identifier
R-HSA-5696096
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Aldehyde dehydrogenase family 3 member B1 ecNumber1.2.1.5/ecNumber, AL3B1_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule membrane proteins (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
ALDH3B1 [plasma membrane] (Homo sapiens)
Exocytosis of specific granule membrane proteins (Homo sapiens)
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
ALDH3B1 [plasma membrane] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Sphingolipid de novo biosynthesis (Homo sapiens)
ALDH3B1 oxidises HXAL to PALM (Homo sapiens)
ALDH3B1 [plasma membrane] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
23721920
Substrate specificity, plasma membrane localization, and lipid modification of the aldehyde dehydrogenase ALDH3B1
Abe, K
,
Nakahara, K
,
Ohno, Y
,
Kitamura, T
,
Kihara, A
,
Naganuma, T
Biochim. Biophys. Acta
2013
External Reference Information
External Reference
UniProt:P43353 ALDH3B1
Gene Names
ALDH3B1, ALDH7
Chain
chain:1-465, propeptide:466-468
Reference Genes
BioGPS Gene:221 ALDH3B1
COSMIC (genes):ALDH3B1 ALDH3B1
CTD Gene:221 ALDH3B1
dbSNP Gene:221 ALDH3B1
ENSEMBL:ENSG00000006534.17 ALDH3B1
HGNC:410 ALDH3B1
KEGG Gene (Homo sapiens):221 ALDH3B1
Monarch:221 ALDH3B1
NCBI Gene:221 ALDH3B1
OMIM:600466 ALDH3B1
UCSC:P43353 ALDH3B1
Reference Transcript
RefSeq:NM_001030010.2 ALDH3B1
RefSeq:NM_001161473.2 ALDH3B1
RefSeq:NM_001290059.1 ALDH3B1
RefSeq:NM_000694.3 ALDH3B1
RefSeq:NM_001290058.1 ALDH3B1
Other Identifiers
11731722_a_at
11731723_a_at
11741146_x_at
16727976
205640_PM_at
205640_at
211004_3p_s_at
211004_PM_s_at
211004_s_at
221
3337330
3337334
3337337
3337338
3337339
3337340
3337341
3337344
3337345
3337346
3337349
3337350
3337352
3337355
3337356
3337357
3337358
3337359
3379095
3379096
3379097
40685_at
7941961
A_24_P218688
A_33_P3236563
A_33_P3367447
GE58922
GO:0003824
GO:0004028
GO:0004029
GO:0004030
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0005886
GO:0006066
GO:0006068
GO:0006081
GO:0006629
GO:0006979
GO:0016020
GO:0016491
GO:0016620
GO:0018477
GO:0018479
GO:0030148
GO:0030667
GO:0031410
GO:0031982
GO:0033721
GO:0034599
GO:0035579
GO:0043226
GO:0046185
GO:0070062
HMNXSV003043545
Hs.87539.0.S1_3p_s_at
ILMN_1727965
ILMN_1728662
PH_hs_0023369
TC11000702.hg
U10868_at
g12803456_3p_a_at
g4502042_3p_at
g4502042_3p_x_at
p33392
p33393
Participates
as a member of
Specific granule membrane proteins [plasma membrane] (Homo sapiens)
Secretory granule membrane proteins [plasma membrane] (Homo sapiens)
Other forms of this molecule
ALDH3B1 [secretory granule membrane]
ALDH3B1 [specific granule membrane]
Inferred To
aldh3b2 [plasma membrane]
(Xenopus tropicalis)
Aldh-III [plasma membrane]
(Drosophila melanogaster)
ALDH3B1 [plasma membrane]
(Bos taurus)
ALDH3B1 [plasma membrane]
(Canis familiaris)
ALDH3B1 [plasma membrane]
(Dictyostelium discoideum)
ALDH3B1 [plasma membrane]
(Gallus gallus)
ALDH3B1 [plasma membrane]
(Mus musculus)
ALDH3B1 [plasma membrane]
(Rattus norvegicus)
ALDH3B1 [plasma membrane]
(Saccharomyces cerevisiae)
ALDH3B1 [plasma membrane]
(Sus scrofa)
alh-4 [plasma membrane]
(Caenorhabditis elegans)
aldh3d1 [plasma membrane]
(Danio rerio)
Modified Residues
Name
S-palmitoyl-L-cysteine at 463
Coordinate
463
PsiMod Name
S-palmitoyl-L-cysteine [MOD:00115]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-palmitoyl-L-cysteine.
Name
S-geranylgeranyl-L-cysteine at 465
Coordinate
465
PsiMod Name
S-geranylgeranyl-L-cysteine [MOD:00113]
PsiMod Definition
A protein modification that effectively converts an L-cysteine residue to S-geranylgeranyl-L-cysteine.
Cross References
RefSeq
NP_001276988.1
,
NP_000685.1
,
NP_001025181.1
,
NP_001276987.1
,
NP_001154945.1
OpenTargets
ENSG00000006534
IntEnz
1.2.1.5
HPA
ENSG00000006534-ALDH3B1
GeneCards
P43353
Ensembl
ENST00000614849
,
ENST00000617288
,
ENSP00000481604
,
ENSG00000006534
,
ENST00000342456
,
ENSP00000478486
,
ENSP00000473990
PRO
P43353
Pharos - Targets
P43353
HMDB Protein
HMDBP00542
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P60410 KRTAP10-8
1
KRTAP10-8 [cytosol]
(R-HSA-6810301)
0.718
6
UniProt:O76011 KRT34
1
KRT34 [cytosol]
(R-HSA-6809608)
0.556
3
IntAct:EBI-10171679 386682
0.556
3
UniProt:P60411 KRTAP10-9
1
KRTAP10-9 [cytosol]
(R-HSA-6810277)
0.556
3
UniProt:Q8IUG1 KRTAP1-3
1
KRTAP1-3 [cytosol]
(R-HSA-6809866)
0.556
3
UniProt:Q7Z3S9 NT2NA
0.556
3
UniProt:Q07627 KRTAP1-1
1
KRTAP1-1 [cytosol]
(R-HSA-6809855)
0.556
3
UniProt:P26371 KRTAP5-9
1
KRTAP5-9 [cytosol]
(R-HSA-6810265)
0.556
3
UniProt:P60370 KRTAP10-5
1
KRTAP10-5 [cytosol]
(R-HSA-6810260)
0.556
3
UniProt:Q6A162 KRT40
1
KRT40 [cytosol]
(R-HSA-6809605)
0.556
3
UniProt:A8MQ03 CRTP1
0.556
3
UniProt:P60409 KRTAP10-7
1
KRTAP10-7 [cytosol]
(R-HSA-6810279)
0.556
3
UniProt:Q15323 KRT31
1
KRT31 [cytosol]
(R-HSA-6809616)
0.556
3
UniProt:P60328 KRTAP12-3
1
KRTAP12-3 [cytosol]
(R-HSA-6810284)
0.556
3
UniProt:Q9UJV3-2 MID2
0.556
3
UniProt:Q9BYR6 KRTAP3-3
1
KRTAP3-3 [cytosol]
(R-HSA-6809859)
0.556
3
UniProt:Q9BYR5 KRTAP4-2
1
KRTAP4-2 [cytosol]
(R-HSA-6809948)
0.488
2
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