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EEF2 [secretory granule lumen]
Stable Identifier
R-HSA-6801504
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
secretory granule lumen
Synonyms
eEF2
Icon
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Neutrophil degranulation (Homo sapiens)
Exocytosis of secretory granule lumen proteins (Homo sapiens)
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
EEF2 [secretory granule lumen] (Homo sapiens)
External Reference Information
External Reference
UniProt:P13639 EEF2
Gene Names
EEF2, EF2
Chain
initiator methionine:1, chain:2-858
Reference Genes
BioGPS Gene:1938 EEF2
COSMIC (genes):EEF2 EEF2
CTD Gene:1938 EEF2
dbSNP Gene:1938 EEF2
ENSEMBL:ENSG00000167658.16 EEF2
HGNC:3214 EEF2
KEGG Gene (Homo sapiens):1938 EEF2
Monarch:1938 EEF2
NCBI Gene:1938 EEF2
OMIM:130610 EEF2
UCSC:P13639 EEF2
Reference Transcript
RefSeq:NM_001961.3 EEF2
Other Identifiers
11715781_a_at
11715782_a_at
11715783_x_at
11748763_a_at
11748764_x_at
11751022_x_at
11757678_s_at
16867212
18671261
18671262
18671263
18671264
18671265
18671266
18671267
18671268
18671269
18671270
18671271
18671273
18671274
18671275
18671276
1938
200094_PM_s_at
200094_s_at
204102_PM_s_at
204102_s_at
36587_at
3846539
3846540
3846541
3846542
3846543
3846544
3846545
3846548
3846549
3846551
3846553
3846555
3846556
3846557
3846559
3846561
3846562
3846563
3846564
3846565
3846567
3846568
3846569
3846570
8032730
A_24_P87763
GE60349
GO:0000166
GO:0002244
GO:0002376
GO:0003723
GO:0003746
GO:0003824
GO:0003924
GO:0005515
GO:0005525
GO:0005576
GO:0005615
GO:0005634
GO:0005737
GO:0005829
GO:0005844
GO:0005886
GO:0006412
GO:0006414
GO:0016020
GO:0016235
GO:0016787
GO:0019901
GO:0030154
GO:0031410
GO:0034774
GO:0043022
GO:0043226
GO:0045182
GO:0045202
GO:0045296
GO:0045727
GO:0048856
GO:0070062
GO:0110165
GO:1904813
GO:1990904
HMNXSV003054355
ILMN_1738383
PH_hs_0004308
TC19001054.hg
X51466_at
g4503482_3p_a_at
Participates
as a member of
Secretory granule lumen proteins [secretory granule lumen] (Homo sapiens)
Other forms of this molecule
EEF2 [ficolin-1-rich granule lumen]
EEF2 [extracellular region]
EEF2 [cytosol]
aminocarboxypropyl EEF2 [cytosol]
Me-diphthine EEF2 [cytosol]
nascent EEF2 [cytosol]
diphthine EEF2 [cytosol]
ADP-ribo-EEF2 [cytosol]
Me3K525-EEF2 [cytosol]
Inferred To
cinC [secretory granule lumen]
(Dictyostelium discoideum)
EEF2 [secretory granule lumen]
(Bos taurus)
EEF2 [secretory granule lumen]
(Caenorhabditis elegans)
EEF2 [secretory granule lumen]
(Canis familiaris)
EEF2 [secretory granule lumen]
(Danio rerio)
EEF2 [secretory granule lumen]
(Dictyostelium discoideum)
EEF2 [secretory granule lumen]
(Drosophila melanogaster)
EEF2 [secretory granule lumen]
(Gallus gallus)
EEF2 [secretory granule lumen]
(Mus musculus)
EEF2 [secretory granule lumen]
(Plasmodium falciparum)
EEF2 [secretory granule lumen]
(Rattus norvegicus)
EEF2 [secretory granule lumen]
(Saccharomyces cerevisiae)
EEF2 [secretory granule lumen]
(Schizosaccharomyces pombe)
EEF2 [secretory granule lumen]
(Sus scrofa)
eef2.1 [secretory granule lumen]
(Xenopus tropicalis)
Homologues of EEF2 [secretory granule lumen]
(Danio rerio)
Homologues of EEF2 [secretory granule lumen]
(Dictyostelium discoideum)
Cross References
RefSeq
NP_001952.1
Guide to Pharmacology - Targets
2756
OpenTargets
ENSG00000167658
GeneCards
P13639
HPA
ENSG00000167658-EEF2
Ensembl
ENSG00000167658
,
ENST00000309311
,
ENSP00000307940
PRO
P13639
Pharos - Targets
P13639
Orphanet
22496
HMDB Protein
HMDBP02947
PDB
6Z6N
,
6Z6M
,
4V6X
,
6D9J
Interactors (6)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P42858 HTT
1
HTT [nucleoplasm]
(R-HSA-9023590)
0.556
3
UniProt:Q9NRI5 DISC1
0.553
2
UniProt:P62993 GRB2
1
GRB2 [cytosol]
(R-HSA-8983328)
0.527
2
UniProt:Q16539 MAPK14
7
MAPK14 [secretory granule lumen]
(R-HSA-6803300)
MAPK14 [extracellular region]
(R-HSA-6806453)
MAPK14 [ficolin-1-rich granule lumen]
(R-HSA-6803280)
MAPK14 [nucleoplasm]
(R-HSA-446223)
MAPK14 [cytosol]
(R-HSA-428933)
p-T180,Y182-MAPK14 [cytosol]
(R-HSA-428935)
p-T180,Y182-MAPK14 [nucleoplasm]
(R-HSA-446227)
0.527
2
UniProt:Q5S007 LRRK2
1
LRRK2 [cytosol]
(R-HSA-5661173)
0.527
3
UniProt:Q99714 HSD17B10
1
HSD17B10 [mitochondrial matrix]
(R-HSA-70831)
0.499
3
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