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HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
Stable Identifier
R-HSA-517624
Type
Complex
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Regulation of mRNA stability by proteins that bind AU-rich elements (Homo sapiens)
HuR (ELAVL1) binds and stabilizes mRNA (Homo sapiens)
HuR:mRNA complex translocates from the nucleus to the cytosol (Homo sapiens)
HuR:mRNA Complex [cytosol] (Homo sapiens)
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol] (Homo sapiens)
Literature References
PubMed ID
Title
Journal
Year
17392515
Protein kinase C alpha-dependent phosphorylation of the mRNA-stabilizing factor HuR: implications for posttranscriptional regulation of cyclooxygenase-2
Doller, A
,
Huwiler, A
,
Müller, R
,
Radeke, HH
,
Pfeilschifter, J
,
Eberhardt, W
Mol Biol Cell
2007
Participants
components
mRNA Transcript Targeted by HuR Phosphorylated on Ser158 and Ser318 [cytosol]
p-S158,S221-ELAVL1 [cytosol]
(Homo sapiens)
Participates
as a member of
HuR:mRNA Complex [cytosol] (Homo sapiens)
Inferred To
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
(Bos taurus)
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
(Canis familiaris)
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
(Danio rerio)
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
(Drosophila melanogaster)
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
(Mus musculus)
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
(Rattus norvegicus)
HuR with phosphoserine221 and phosphoserine158:mRNA Complex [cytosol]
(Sus scrofa)
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