Reactome | 2xMe-SNRPD1 [nucleoplasm]

2xMe-SNRPD1 [nucleoplasm]

Stable Identifier

R-HSA-192215

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

dimethylated Sm protein D1, snRNP core protein D1, Small nuclear ribonucleoprotein Sm D1, Sm-D1, Sm-D autoantigen

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62314 SNRPD1

Gene Names

SNRPD1

Chain

chain:1-119

Reference Genes

BioGPS Gene:6632 SNRPD1

COSMIC (genes):SNRPD1 SNRPD1

CTD Gene:6632 SNRPD1

dbSNP Gene:6632 SNRPD1

ENSEMBL:ENSG00000167088 SNRPD1

ENSEMBL_homo_sapiens_GENE:ENSG00000167088.11 SNRPD1

HGNC:11158 SNRPD1

KEGG Gene (Homo sapiens):6632 SNRPD1

Monarch:6632 SNRPD1

NCBI Gene:6632 SNRPD1

OMIM:601063 SNRPD1

UCSC:P62314 SNRPD1

Reference Transcript

Other Identifiers

11724202_s_at

11724203_at

11724204_s_at

16851344

202690_PM_s_at

202690_s_at

202691_PM_at

202691_at

2409583

2409584

3781089

3781090

3781091

3781092

3781094

3781095

3781099

3781100

3781101

3781102

3781103

3781104

3781105

3781106

37949_at

6632

8020411

A_23_P107644

GE57489

GO:0000243

GO:0000245

GO:0000387

GO:0000398

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005682

GO:0005684

GO:0005685

GO:0005686

GO:0005687

GO:0005689

GO:0005737

GO:0005829

GO:0006396

GO:0006397

GO:0008380

GO:0016071

GO:0030532

GO:0034709

GO:0034715

GO:0034719

GO:0036261

GO:0043226

GO:0043229

GO:0046540

GO:0065003

GO:0071005

GO:0071007

GO:0071011

GO:0071013

GO:0097526

GO:1903241

GO:1990904

HMNXSV003031774

HMNXSV003052360

ILMN_1768393

J03798_at

PH_hs_0004884

TC18000088.hg

g12804598_3p_a_at

g5902101_3p_at

p7928

Participates

as a component of

Other forms of this molecule

SNRPD1 [cytosol]

2xMe-SNRPD1 [cytosol]

Inferred To

smd1 [nucleoplasm] (Schizosaccharomyces pombe)

SMD1 [nucleoplasm] (Saccharomyces cerevisiae)

2xMe-SNRPD1 [nucleoplasm] (Gallus gallus)

2xMe-SNRPD1 [nucleoplasm] (Plasmodium falciparum)

2xMe-SNRPD1 [nucleoplasm] (Rattus norvegicus)

2xMe-SNRPD1 [nucleoplasm] (Sus scrofa)

SmD1 [nucleoplasm] (Drosophila melanogaster)

snrpd1 [nucleoplasm] (Danio rerio)

snrpd1 [nucleoplasm] (Xenopus tropicalis)

snrpD1 [nucleoplasm] (Dictyostelium discoideum)

snr-3 [nucleoplasm] (Caenorhabditis elegans)

SNRPD1 [nucleoplasm] (Bos taurus)

SNRPD1 [nucleoplasm] (Canis familiaris)

Snrpd1 [nucleoplasm] (Mus musculus)

Modified Residues

Name

monomethylated residue at unknown position

PsiMod Name

monomethylated residue [MOD:00599]

PsiMod Definition

A protein modification that effectively replaces one hydrogen atom with one methyl group.

Name

monomethylated residue at unknown position

PsiMod Name

monomethylated residue [MOD:00599]

PsiMod Definition

A protein modification that effectively replaces one hydrogen atom with one methyl group.

Cross References

RefSeq

NP_008869.1, NP_001278845.1

OpenTargets

ENSG00000167088

GeneCards

P62314

HPA

ENSG00000167088-SNRPD1

Ensembl

ENST00000300413, ENSG00000167088, ENSP00000300413

PRO

P62314

Pharos - Targets

P62314

PDB

8RC0, 8CH6, 5O9Z, 4F7U, 7EVO, 8Y7E, 6QW6, 7ABG, 1B34, 8Q91, 7ABI, 6AH0, 6Y53, 6ICZ, 6ID1, 7W5B, 5Z57, 8C6J, 7B0Y, 5Z56, 6QX9, 5Z58, 3JCR, 6FF7, 4WZJ, 3PGW, 6ID0, 7QTT, 7W5A, 6Y5Q, 6AHD, 8Q7V, 4V98, 5XJU, 3CW1, 5XJS, 8QO9, 7VPX, 7DVQ, 5XJT, 8Q7Q, 5YZG, 8HK1, 5XJQ, 7A5P, 5XJR, 8Y6O, 6QDV, 5XJC, 5MQF, 7W59, 8Q7X, 4PJO, 8Q7W, 5XJL

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P54105 CLNS1A	1	CLNS1A [cytosol] (R-HSA-191796)	0.882	13
UniProt:Q16637 SMN1	2	SMN1 [nucleoplasm] (R-HSA-191892) SMN1 [cytosol] (R-HSA-191839)	0.839	7
UniProt:P14678 SNRPB	4	SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.793	5
UniProt:O14893 GEMIN2	2	GEMIN2 [nucleoplasm] (R-HSA-191795) GEMIN2 [cytosol] (R-HSA-191835)	0.708	5
UniProt:P62316 SNRPD2	2	SNRPD2 [nucleoplasm] (R-HSA-71901) SNRPD2 [cytosol] (R-HSA-191810)	0.678	4
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.669	5
UniProt:O95400 CD2BP2	1	CD2BP2 [nucleoplasm] (R-HSA-72054)	0.643	4
UniProt:P08621 SNRNP70	1	SNRNP70 [nucleoplasm] (R-HSA-71913)	0.643	6
UniProt:P62306 SNRPF	2	SNRPF [nucleoplasm] (R-HSA-71907) SNRPF [cytosol] (R-HSA-191852)	0.643	4
UniProt:P27958-PRO_0000037573			0.602	7
UniProt:Q15428 SF3A2	1	SF3A2 [nucleoplasm] (R-HSA-71964)	0.564	2
UniProt:P62310 LSM3	2	LSM3 [nucleoplasm] (R-HSA-6806807) LSM3 [cytosol] (R-HSA-429894)	0.547	2
UniProt:Q8WXD5 GEMIN6	2	GEMIN6 [nucleoplasm] (R-HSA-191799) GEMIN6 [cytosol] (R-HSA-191771)	0.544	2
UniProt:P62312 LSM6	2	LSM6 [cytosol] (R-HSA-429936) LSM6 [nucleoplasm] (R-HSA-6806794)	0.527	3
UniProt:P09661 SNRPA1	1	SNRPA1 [nucleoplasm] (R-HSA-71958)	0.527	4
UniProt:P09234 SNRPC	1	SNRPC [nucleoplasm] (R-HSA-8865876)	0.527	3
UniProt:P35637 FUS	1	FUS [nucleoplasm] (R-HSA-72040)	0.527	2
UniProt:Q8TEQ6 GEMIN5	2	GEMIN5 [cytosol] (R-HSA-191833) GEMIN5 [nucleoplasm] (R-HSA-191765)	0.527	2
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.527	3
UniProt:P08579 SNRPB2	1	SNRPB2 [nucleoplasm] (R-HSA-71960)	0.527	2
UniProt:O43395 PRPF3	1	PRPF3 [nucleoplasm] (R-HSA-6806806)	0.527	2
UniProt:Q8WWY3 PRPF31	1	PRPF31 [nucleoplasm] (R-HSA-6806772)	0.508	2
UniProt:P14678-2 SNRPB			0.499	2

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