Reactome | CD2BP2 [nucleoplasm]

CD2BP2 [nucleoplasm]

Stable Identifier

R-HSA-72054

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

CD2BP2 - GYF, CD2 antigen cytoplasmic tail-binding protein 2, CD2 cytoplasmic domain binding protein, CD2 tail binding protein

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:O95400 CD2BP2

Gene Names

CD2BP2, KIAA1178

Chain

chain:1-341

Reference Genes

BioGPS Gene:10421 CD2BP2

COSMIC (genes):CD2BP2 CD2BP2

CTD Gene:10421 CD2BP2

dbSNP Gene:10421 CD2BP2

ENSEMBL:ENSG00000169217 CD2BP2

HGNC:1656 CD2BP2

KEGG Gene (Homo sapiens):10421 CD2BP2

Monarch:10421 CD2BP2

NCBI Gene:10421 CD2BP2

OMIM:604470 CD2BP2

UCSC:O95400 CD2BP2

Reference Transcript

Other Identifiers

0004670091

10421

11719703_a_at

11719704_at

16825753

1GYF

1L2Z

1SYX

202256_at

202257_s_at

3071385

3071391

33801_at

3687699

3687700

3687701

3687702

3687703

3687704

3687705

3687707

3687708

3687709

3687710

3687711

3687712

41508

4BWS

52454_at

61309

78483_at

8000848

A0A024QZC1

A_23_P61551

A_24_P236522

AAC84141

AAH00495

AAH01947

AB033004

AF104222

AK315708

ALQ33976

BAA86492

BAG38069

BC000495

BC001947

CCDS10675

CD2BP2

CD2BP2-201

CD2BP2-203

CH471192

EAW52260

EAW52261

ENSG00000169217

ENSP00000304903

ENSP00000456935

ENST00000305596

ENST00000305596.7

ENST00000569466

ENST00000569466.1

EntrezGene:10421

EntrezGene:CD2BP2

g5174408_3p_a_at

GE541181

GE62041

GO:0000244

GO:0000398

GO:0001650

GO:0003674

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005634

GO:0005654

GO:0005682

GO:0005730

GO:0005737

GO:0005829

GO:0006397

GO:0008150

GO:0008380

GO:0010923

GO:0016607

GO:0022607

GO:0022618

GO:0032991

GO:0034641

GO:0043021

GO:0043226

GO:0065003

HGNC:1656

HPA041508

HPA061309

Hs.202677.0.S2_3p_at

ILMN_1796244

ILMN_1807264

IPR003169

IPR035445

IPR039905

KU178518

MIM:604470

NM_001243646

NM_006110

NP_001230575

NP_006101

PF02213

PH_hs_0011936

SM00444

TC16001027.hg

TC16001840.hg

UPI000006D625

Participant Of

input

Formation of the Spliceosomal E complex

hasComponent

Inferred To

Cd2bp2 [nucleoplasm] (Mus musculus)

Cd2bp2 [nucleoplasm] (Rattus norvegicus)

CD2BP2 [nucleoplasm] (Bos taurus)

CD2BP2 [nucleoplasm] (Canis familiaris)

CD2BP2 [nucleoplasm] (Dictyostelium discoideum)

CD2BP2 [nucleoplasm] (Plasmodium falciparum)

CD2BP2 [nucleoplasm] (Schizosaccharomyces pombe)

CD2BP2 [nucleoplasm] (Sus scrofa)

cd2bp2 [nucleoplasm] (Danio rerio)

cd2bp2 [nucleoplasm] (Xenopus tropicalis)

teg-1 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of CD2BP2 [nucleoplasm] (Gallus gallus)

holn1 [nucleoplasm] (Drosophila melanogaster)

Cross References

RefSeq

NP_001230575.1, NP_006101.1

OpenTargets

ENSG00000169217

HPA

ENSG00000169217-CD2BP2

GeneCards

O95400

Ensembl

ENSP00000304903, ENSG00000169217, ENST00000569466, ENST00000305596, ENSP00000456935

PRO

O95400

PDB

4BWS, 1L2Z, 1SYX, 1GYF

Interactors (24)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06729 CD2	1	CD2 [plasma membrane] (R-HSA-197795)	0.931	16
UniProt:O94906 PRPF6	1	PRPF6 [nucleoplasm] (R-HSA-71881)	0.892	8
UniProt:P14678-2 SNRPB			0.851	9
UniProt:P14678 SNRPB	4	2xMe-SNRPB [cytosol] (R-HSA-192218) SNRPB [cytosol] (R-HSA-191798) SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213)	0.793	10
UniProt:Q9UHR6 ZNHI2			0.666	4
UniProt:Q709F0 ACAD11	1	ACAD11 [mitochondrial inner membrane] (R-HSA-5695987)	0.666	4
UniProt:Q6P2Q9 PRPF8	1	PRPF8 [nucleoplasm] (R-HSA-83810)	0.657	3
UniProt:O75643 SNRNP200	1	SNRNP200 [nucleoplasm] (R-HSA-71885)	0.657	3
UniProt:P83876 TXNL4A	1	TXNL4A [nucleoplasm] (R-HSA-71875)	0.647	3
UniProt:P46934 NEDD4	1	NEDD4 [cytosol] (R-HSA-975992)	0.623	2
UniProt:Q9Y5V3 MAGED1	1	MAGED1 [cytosol] (R-HSA-196002)	0.618	3
UniProt:P62136 PPP1CA	1	PPP1CA [cytosol] (R-HSA-163525)	0.592	2
UniProt:P63162 SNRPN	1	Me2-R108,R112-SNRPN [nucleoplasm] (R-HSA-8865931)	0.59	6
UniProt:Q53GS9 USP39	1	USP39 [nucleoplasm] (R-HSA-6806793)	0.589	2
UniProt:Q15029 EFTUD2	1	EFTUD2 [nucleoplasm] (R-HSA-71883)	0.564	2
UniProt:P62306 SNRPF	2	SNRPF [nucleoplasm] (R-HSA-71907) SNRPF [cytosol] (R-HSA-191852)	0.564	2
UniProt:Q9BUQ8 DDX23	1	DDX23 [nucleoplasm] (R-HSA-71879)	0.564	2
UniProt:Q96DI7 SNRNP40	1	SNRNP40 [nucleoplasm] (R-HSA-71877)	0.564	2
UniProt:Q7Z591 AKNA			0.558	2
UniProt:P36873 PPP1CC	1	PPP1CC [cytosol] (R-HSA-163443)	0.556	3
UniProt:O75865-2 TRAPPC6A			0.556	3
UniProt:Q92530 PSMF1	2	PSMF1 [cytosol] (R-HSA-68818) PSMF1 [nucleoplasm] (R-HSA-174308)	0.527	2
UniProt:Q9Y2W2 WBP11	1	WBP11 [nucleoplasm] (R-HSA-8867887)	0.527	2
UniProt:Q2TAY7 SMU1			0.502	2

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