Reactome | GEMIN5 [cytosol]

GEMIN5 [cytosol]

Stable Identifier

R-HSA-191833

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Gemin 5

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 modulates host translation machinery (Homo sapiens)
        
        snRNP complex assembly (Homo sapiens)
        
        SMN:SM protein complex [cytosol] (Homo sapiens)
        
        SMN complex [cytosol] (Homo sapiens)
        
        GEMIN5 [cytosol] (Homo sapiens)
        
        Spliceosomal m7G capped snRNAs with SMN:SM protein complex bound [cytosol] (Homo sapiens)
        
        SMN:SM protein complex [cytosol] (Homo sapiens)
        
        SMN complex [cytosol] (Homo sapiens)
        
        GEMIN5 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8TEQ6 GEMIN5

Gene Names

GEMIN5

Chain

chain:1-1508

Reference Genes

BioGPS Gene:25929 GEMIN5

COSMIC (genes):GEMIN5 GEMIN5

CTD Gene:25929 GEMIN5

dbSNP Gene:25929 GEMIN5

ENSEMBL:ENSG00000082516 GEMIN5

ENSEMBL_homo_sapiens_GENE:ENSG00000082516.9 GEMIN5

HGNC:20043 GEMIN5

Monarch:25929 GEMIN5

NCBI Gene:25929 GEMIN5

OMIM:607005 GEMIN5

UCSC:Q8TEQ6 GEMIN5

Reference Transcript

Other Identifiers

11742740_at

11742741_at

17002078

225712_PM_at

225712_at

25929

2882898

2882899

2882900

2882901

2882903

2882905

2882906

2882907

2882908

2882909

2882910

2882911

2882913

2882914

2882915

2882917

2882919

2882921

2882923

2882924

2882926

2882927

2882929

2882930

2882931

2882932

2882933

2882934

2882935

2882936

2882937

2882938

2882939

2882940

2882941

2882942

2882943

2882944

2882945

43953_at

44565_at

48446_at

8115410

A_23_P336513

GE56535

GO:0000340

GO:0000387

GO:0000398

GO:0003723

GO:0003730

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006397

GO:0006412

GO:0006417

GO:0008380

GO:0016020

GO:0016071

GO:0016604

GO:0017069

GO:0030619

GO:0030621

GO:0030622

GO:0032797

GO:0034718

GO:0034719

GO:0043022

GO:0043226

GO:0065003

GO:0097504

HMNXSV003057630

Hs.25882.0.S1_3p_at

ILMN_1663383

PH_hs_0002275

TC05001974.hg

Participates

as a component of

SMN complex [cytosol] (Homo sapiens)

Other forms of this molecule

GEMIN5 [nucleoplasm]

Inferred To

gemin5 [cytosol] (Dictyostelium discoideum)

gemin5 [cytosol] (Xenopus tropicalis)

Gemin5 [cytosol] (Mus musculus)

Gemin5 [cytosol] (Rattus norvegicus)

GEMIN5 [cytosol] (Bos taurus)

GEMIN5 [cytosol] (Canis familiaris)

GEMIN5 [cytosol] (Gallus gallus)

GEMIN5 [cytosol] (Sus scrofa)

Ghost homologue of GEMIN5 [cytosol] (Caenorhabditis elegans)

Ghost homologue of GEMIN5 [cytosol] (Danio rerio)

Cross References

RefSeq

NP_056280.2, NP_001239085.1

OpenTargets

ENSG00000082516

GeneCards

Q8TEQ6

HPA

ENSG00000082516-GEMIN5

Ensembl

ENSP00000285873, ENSG00000082516, ENST00000285873

PRO

Q8TEQ6

Pharos - Targets

Q8TEQ6

PDB

5H3U, 5H1M, 5THA, 5H3T, 5GXI, 5H1L, 6RNS, 5TEF, 5H3S, 5GXH, 5H1K, 5TEE, 7XGR, 7XDT, 6RNQ, 5H1J

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.623	3
UniProt:P06730 EIF4E	1	EIF4E [cytosol] (R-HSA-72578)	0.582	3
UniProt:P62318 SNRPD3	3	2xMe-SNRPD3 [nucleoplasm] (R-HSA-192219) SNRPD3 [nucleoplasm] (R-HSA-71903) 2xMe-SNRPD3 [cytosol] (R-HSA-191781)	0.527	2
UniProt:Q9Y3F4 STRAP	1	STRAP [cytosol] (R-HSA-2127556)	0.527	2
UniProt:P62314 SNRPD1	3	2xMe-SNRPD1 [nucleoplasm] (R-HSA-192215) SNRPD1 [cytosol] (R-HSA-191890) 2xMe-SNRPD1 [cytosol] (R-HSA-192217)	0.527	2