Reactome | GEMIN6 [cytosol]

GEMIN6 [cytosol]

Stable Identifier

R-HSA-191771

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Gemin 6

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 modulates host translation machinery (Homo sapiens)
        
        snRNP complex assembly (Homo sapiens)
        
        SMN:SM protein complex [cytosol] (Homo sapiens)
        
        SMN complex [cytosol] (Homo sapiens)
        
        GEMIN6 [cytosol] (Homo sapiens)
        
        Spliceosomal m7G capped snRNAs with SMN:SM protein complex bound [cytosol] (Homo sapiens)
        
        SMN:SM protein complex [cytosol] (Homo sapiens)
        
        SMN complex [cytosol] (Homo sapiens)
        
        GEMIN6 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q8WXD5 GEMIN6

Gene Names

GEMIN6

Chain

chain:1-167

Reference Genes

BioGPS Gene:79833 GEMIN6

COSMIC (genes):GEMIN6 GEMIN6

CTD Gene:79833 GEMIN6

dbSNP Gene:79833 GEMIN6

ENSEMBL:ENSG00000152147 GEMIN6

ENSEMBL_homo_sapiens_GENE:ENSG00000152147.11 GEMIN6

HGNC:20044 GEMIN6

KEGG Gene (Homo sapiens):79833 GEMIN6

Monarch:79833 GEMIN6

NCBI Gene:79833 GEMIN6

OMIM:607006 GEMIN6

UCSC:Q8WXD5 GEMIN6

Reference Transcript

RefSeq:NM_024775.9 GEMIN6

Other Identifiers

11755600_a_at

16879265

219539_PM_at

219539_at

230118_PM_at

230118_at

2477983

2477987

2477990

2477991

2478010

54949_at

58220_at

79833

8041553

A_23_P56567

A_32_P135601

GE87101

GE895898

GO:0000245

GO:0000387

GO:0000398

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006397

GO:0008380

GO:0016071

GO:0016604

GO:0032797

GO:0034719

GO:0043226

GO:0065003

GO:0097504

HMNXSV003033497

Hs.109154.0.A1_3p_at

ILMN_1707484

PH_hs_0008480

g13376126_3p_at

Participates

as a component of

SMN complex [cytosol] (Homo sapiens)

Other forms of this molecule

GEMIN6 [nucleoplasm]

Inferred To

Ghost homologue of GEMIN6 [cytosol] (Danio rerio)

Ghost homologue of GEMIN6 [cytosol] (Dictyostelium discoideum)

Ghost homologue of GEMIN6 [cytosol] (Xenopus tropicalis)

Gemin6 [cytosol] (Mus musculus)

Gemin6 [cytosol] (Rattus norvegicus)

GEMIN6 [cytosol] (Bos taurus)

GEMIN6 [cytosol] (Caenorhabditis elegans)

GEMIN6 [cytosol] (Canis familiaris)

GEMIN6 [cytosol] (Gallus gallus)

GEMIN6 [cytosol] (Sus scrofa)

Cross References

RefSeq

NP_079051.9

OpenTargets

ENSG00000152147

GeneCards

Q8WXD5

HPA

ENSG00000152147-GEMIN6

Ensembl

ENST00000281950, ENSG00000152147, ENSP00000281950

PRO

Q8WXD5

Pharos - Targets

Q8WXD5

PDB

7BBL, 1Y96

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y3F4 STRAP	1	STRAP [cytosol] (R-HSA-2127556)	0.759	6
UniProt:P62306 SNRPF	2	SNRPF [nucleoplasm] (R-HSA-71907) SNRPF [cytosol] (R-HSA-191852)	0.759	5
UniProt:P62304 SNRPE	2	SNRPE [nucleoplasm] (R-HSA-71905) SNRPE [cytosol] (R-HSA-191782)	0.688	5
UniProt:P62316 SNRPD2	2	SNRPD2 [nucleoplasm] (R-HSA-71901) SNRPD2 [cytosol] (R-HSA-191810)	0.59	2
UniProt:P62308 SNRPG	2	SNRPG [nucleoplasm] (R-HSA-71909) SNRPG [cytosol] (R-HSA-191827)	0.59	3
UniProt:P62314 SNRPD1	3	2xMe-SNRPD1 [nucleoplasm] (R-HSA-192215) SNRPD1 [cytosol] (R-HSA-191890) 2xMe-SNRPD1 [cytosol] (R-HSA-192217)	0.544	2
UniProt:P14678 SNRPB	4	SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [cytosol] (R-HSA-191798) 2xMe-SNRPB [cytosol] (R-HSA-192218)	0.527	2