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SNRPB2 [nucleoplasm]
Stable Identifier
R-HSA-71960
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
U2 B' protein, U2 small nuclear ribonucleoprotein B
Locations in the PathwayBrowser
Expand all
Metabolism of RNA (Homo sapiens)
Processing of Capped Intron-Containing Pre-mRNA (Homo sapiens)
mRNA Splicing (Homo sapiens)
mRNA Splicing - Major Pathway (Homo sapiens)
Disassembly of the Intron Lariat Spliceosome (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal A complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal B* complex (Homo sapiens)
Spliceosomal B* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Bact complex (Homo sapiens)
Spliceosomal B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal Bact complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal C* complex (Homo sapiens)
Spliceosomal C complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal P complex and exon ligation (Homo sapiens)
Spliceosomal C* complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Formation of the Spliceosomal Pre-B complex (Homo sapiens)
Spliceosomal A complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal Pre-B complex [nucleoplasm] (Homo sapiens)
U2 snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex dissociates yielding the intron-containing complex (ILS) and the spliced mRNP (new) (Homo sapiens)
Intron Lariat Spliceosome (ILS) [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
Spliceosomal P complex [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
SNRPB2 [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:P08579 SNRPB2
Gene Names
SNRPB2
Chain
chain:1-225
Reference Genes
BioGPS Gene:6629 SNRPB2
COSMIC (genes):SNRPB2 SNRPB2
CTD Gene:6629 SNRPB2
dbSNP Gene:6629 SNRPB2
ENSEMBL:ENSG00000125870 SNRPB2
ENSEMBL_homo_sapiens_GENE:ENSG00000125870.11 SNRPB2
HGNC:11155 SNRPB2
KEGG Gene (Homo sapiens):6629 SNRPB2
Monarch:6629 SNRPB2
NCBI Gene:6629 SNRPB2
OMIM:603520 SNRPB2
UCSC:P08579 SNRPB2
Reference Transcript
RefSeq:NM_198220.2 SNRPB2
RefSeq:NM_003092.4 SNRPB2
Other Identifiers
11731480_a_at
11744212_x_at
11753546_a_at
11756021_x_at
16911605
202505_PM_at
202505_at
2978761
2978763
2978764
38399_at
3877779
3877780
3877781
3877782
3877788
3877789
3877790
3877793
3877796
3877799
3877801
3877802
3877803
3877804
3877805
3877806
3877808
44293_at
6629
74555_at
8061075
A_23_P40307
A_24_P194260
GE61284
GO:0000398
GO:0001650
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005681
GO:0005684
GO:0005685
GO:0005686
GO:0005730
GO:0006397
GO:0008380
GO:0016071
GO:0016607
GO:0030532
GO:0030619
GO:0036464
GO:0043226
GO:0065003
GO:0070990
GO:0071005
GO:0071007
GO:0071013
GO:1903241
GO:1990904
HMNXSV003028131
ILMN_1690706
ILMN_1771620
M15841_at
PH_hs_0029603
TC20000104.hg
TC20001115.hg
g4507122_3p_at
Participates
as a component of
U2 snRNP [nucleoplasm] (Homo sapiens)
U2 12S snRNP [nucleoplasm] (Homo sapiens)
Inferred To
snf [nucleoplasm]
(Drosophila melanogaster)
SNRPB2 [nucleoplasm]
(Gallus gallus)
SNRPB2 [nucleoplasm]
(Plasmodium falciparum)
SNRPB2 [nucleoplasm]
(Sus scrofa)
Snrpb2 [nucleoplasm]
(Mus musculus)
Homologues of SNRPB2 [nucleoplasm]
(Plasmodium falciparum)
snrpb2 [nucleoplasm]
(Danio rerio)
snrpb2 [nucleoplasm]
(Dictyostelium discoideum)
snrpb2 [nucleoplasm]
(Xenopus tropicalis)
LOC100686524 [nucleoplasm]
(Canis familiaris)
usp102 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of SNRPB2 [nucleoplasm]
(Bos taurus)
Ghost homologue of SNRPB2 [nucleoplasm]
(Rattus norvegicus)
rnp-2 [nucleoplasm]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_937863.1
,
NP_003083.1
OpenTargets
ENSG00000125870
HPA
ENSG00000125870-SNRPB2
GeneCards
P08579
Ensembl
ENSP00000367178
,
ENST00000377943
,
ENSP00000246071
,
ENSG00000125870
,
ENST00000246071
PRO
P08579
Pharos - Targets
P08579
PDB
7VPX
,
5YZG
,
6ID0
,
5O9Z
,
5XJC
,
6QDV
,
5MQF
,
5Z57
,
5Z58
,
6ICZ
,
8QO9
,
6Y5Q
,
7W5A
,
8C6J
,
6AHD
,
8HK1
,
6FF7
,
5Z56
,
7W5B
,
7EVO
,
7ABI
,
6AH0
,
7W59
,
6Y53
,
1A9N
,
8CH6
,
7A5P
,
7ABG
,
6QX9
,
6ID1
Interactors (17)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P09661 SNRPA1
1
SNRPA1 [nucleoplasm]
(R-HSA-71958)
0.833
9
UniProt:P14373 TRIM27
2
TRIM27 [nucleoplasm]
(R-HSA-2997690)
TRIM27 [cytosol]
(R-HSA-8851002)
0.718
6
UniProt:P62306 SNRPF
2
SNRPF [nucleoplasm]
(R-HSA-71907)
SNRPF [cytosol]
(R-HSA-191852)
0.643
5
UniProt:P62304 SNRPE
2
SNRPE [nucleoplasm]
(R-HSA-71905)
SNRPE [cytosol]
(R-HSA-191782)
0.643
5
UniProt:P62318 SNRPD3
3
SNRPD3 [nucleoplasm]
(R-HSA-71903)
2xMe-SNRPD3 [nucleoplasm]
(R-HSA-192219)
2xMe-SNRPD3 [cytosol]
(R-HSA-191781)
0.564
3
UniProt:P13196 ALAS1
2
PXLP-ALAS1 [mitochondrial matrix]
(R-HSA-1022086)
ALAS1 [mitochondrial matrix]
(R-HSA-189438)
0.556
3
UniProt:Q08379 GOLGA2
3
p-S37-GOLGA2 [Golgi membrane]
(R-HSA-2172179)
GOLGA2 [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-2167933)
GOLGA2 [Golgi membrane]
(R-HSA-6808764)
0.556
3
UniProt:Q14566 MCM6
1
MCM6 [nucleoplasm]
(R-HSA-68553)
0.556
3
UniProt:Q9NRD5 PICK1
2
PICK1 [endocytic vesicle membrane]
(R-HSA-417017)
PICK1 [plasma membrane]
(R-HSA-416989)
0.556
3
UniProt:Q8IWZ8 SUGP1
1
SUGP1 [nucleoplasm]
(R-HSA-72043)
0.547
2
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.527
2
UniProt:O43719 HTATSF1
1
HTATSF1 [nucleoplasm]
(R-HSA-9770246)
0.527
4
UniProt:P62316 SNRPD2
2
SNRPD2 [nucleoplasm]
(R-HSA-71901)
SNRPD2 [cytosol]
(R-HSA-191810)
0.527
5
UniProt:O75533 SF3B1
1
SF3B1 [nucleoplasm]
(R-HSA-71968)
0.527
5
UniProt:P14678 SNRPB
4
SNRPB [nucleoplasm]
(R-HSA-71896)
Me2-R108,R112-SNRPB [nucleoplasm]
(R-HSA-192213)
SNRPB [cytosol]
(R-HSA-191798)
2xMe-SNRPB [cytosol]
(R-HSA-192218)
0.527
5
UniProt:P62314 SNRPD1
3
2xMe-SNRPD1 [nucleoplasm]
(R-HSA-192215)
SNRPD1 [cytosol]
(R-HSA-191890)
2xMe-SNRPD1 [cytosol]
(R-HSA-192217)
0.527
2
UniProt:O75937 DNAJC8
1
DNAJC8 [nucleoplasm]
(R-HSA-53703)
0.508
2
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