Reactome | LSM6 [cytosol]

LSM6 [cytosol]

Stable Identifier

R-HSA-429936

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

U6 snRNA-associated Sm-like protein LSm6, LSM6_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P62312 LSM6

Gene Names

LSM6

Chain

chain:1-80

Reference Genes

BioGPS Gene:11157 LSM6

COSMIC - genes:LSM6 LSM6

CTD Gene:11157 LSM6

dbSNP Gene:11157 LSM6

ENSEMBL:ENSG00000164167 LSM6

HGNC:17017 LSM6

KEGG:hsa:11157 LSM6

Monarch:11157 LSM6

NCBI Gene:11157 LSM6

OMIM:607286 LSM6

UCSC:P62312 LSM6

Reference Transcript

Other Identifiers

11157

11721137_a_at

11721138_x_at

16971226

205036_PM_at

205036_at

2746292

2746293

2746294

2746295

2746296

2746297

2746298

2746299

2746300

2746303

2746304

2746307

2746308

2746309

2746310

2746311

2746312

2746313

2746314

2746315

2746316

2746317

2746318

2746319

2746320

2746321

2746322

2746324

2746326

2746328

35991_at

3810955

8097679

A_14_P109721

A_14_P115263

A_23_P259451

GE55262

GO:0000398

GO:0000932

GO:0003723

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005688

GO:0005730

GO:0005732

GO:0005737

GO:0005829

GO:0006364

GO:0006397

GO:0006399

GO:0006402

GO:0008033

GO:0008380

GO:0016071

GO:0030490

GO:0030532

GO:0043226

GO:0046540

GO:0046982

GO:0071005

GO:0120115

GO:1990904

HMNXSV003040144

ILMN_1675462

PH_hs_0022666

PH_hs_0038133

TC04000717.hg

TC04002247.hg

g5901997_3p_at

Participates

as a component of

Lsm1-7 Complex [cytosol] (Homo sapiens)

Other forms of this molecule

LSM6 [nucleoplasm]

Inferred To

Dmel\CG9344 [cytosol] (Drosophila melanogaster)

LSM6 [cytosol] (Bos taurus)

LSM6 [cytosol] (Canis familiaris)

LSM6 [cytosol] (Gallus gallus)

LSM6 [cytosol] (Plasmodium falciparum)

LSM6 [cytosol] (Saccharomyces cerevisiae)

LSM6 [cytosol] (Sus scrofa)

lsm6 [cytosol] (Dictyostelium discoideum)

lsm6 [cytosol] (Schizosaccharomyces pombe)

lsm6 [cytosol] (Xenopus tropicalis)

Ghost homologue of LSM6 [cytosol] (Danio rerio)

Lsm6 [cytosol] (Mus musculus)

Lsm6 [cytosol] (Rattus norvegicus)

lsm-6 [cytosol] (Caenorhabditis elegans)

Cross References

RefSeq

XP_054204811.1, XP_016863162.1, XP_016863161.1, NP_009011.1, XP_054204810.1

OpenTargets

ENSG00000164167

ENSEMBL

ENST00000504181, ENST00000296581, ENST00000649747, ENSP00000422392, ENST00000502781, ENST00000515311, ENSG00000164167, ENSP00000497311, ENSP00000427036, ENSP00000420929, ENSP00000296581

HPA

ENSG00000164167-LSM6

GeneCards

LSM6

PRO

P62312

Pharos - Targets

P62312

GlyGen

P62312

PDB

6QX9, 5O9Z, 7ABG, 6AH0, 8H6K, 8R0B, 8H6L, 8H6J, 3JCR, 8H6E, 8R0A, 8R09, 8QO9, 8RM5, 6QW6, 8R08, 8QZS, 8QXD, 6AHD

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P62316 SNRPD2	2	SNRPD2 [cytosol] (R-HSA-191810) SNRPD2 [nucleoplasm] (R-HSA-71901)	0.804	6
UniProt:O00560 SDCBP	3	SDCBP [cytosol] (R-HSA-373639) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [extracellular region] (R-HSA-6806206)	0.718	6
UniProt:P62306 SNRPF	2	SNRPF [cytosol] (R-HSA-191852) SNRPF [nucleoplasm] (R-HSA-71907)	0.659	3
UniProt:Q9BRS2 RIOK1	2	RIOK1 [nucleoplasm] (R-HSA-5226890) RIOK1 [cytosol] (R-HSA-6791525)	0.643	4
UniProt:Q9NQ92 COPRS	1	COPRS [nucleoplasm] (R-HSA-5212681)	0.643	3
UniProt:O75554 WBP4	1	WBP4 [nucleoplasm] (R-HSA-8867895)	0.527	2
UniProt:Q9BQA1 WDR77	3	WDR77 [cytosol] (R-HSA-191823) pT5-WDR77 [nucleoplasm] (R-HSA-5205602) WDR77 [nucleoplasm] (R-HSA-5205610)	0.527	2
UniProt:P14678 SNRPB	4	2xMe-SNRPB [cytosol] (R-HSA-192218) SNRPB [cytosol] (R-HSA-191798) SNRPB [nucleoplasm] (R-HSA-71896) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213)	0.527	2
UniProt:P62304 SNRPE	2	SNRPE [cytosol] (R-HSA-191782) SNRPE [nucleoplasm] (R-HSA-71905)	0.527	2
UniProt:P62314 SNRPD1	3	2xMe-SNRPD1 [cytosol] (R-HSA-192217) SNRPD1 [cytosol] (R-HSA-191890) 2xMe-SNRPD1 [nucleoplasm] (R-HSA-192215)	0.527	3
UniProt:O14744 PRMT5	3	PRMT5 [cytosol] (R-HSA-191876) PRMT5 [nucleoplasm] (R-HSA-5205609) p-Y297,304,307-PRMT5 [nucleoplasm] (R-HSA-5211300)	0.527	3

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