Reactome | SNRNP70 [nucleoplasm]

SNRNP70 [nucleoplasm]

Stable Identifier

R-HSA-71913

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

U1 - 70K protein, RU17_HUMAN, U1 small nuclear ribonucleoprotein 70 kDa, U1 snRNP 70 kDa, snRNP70, U1-70K

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P08621 SNRNP70

Gene Names

SNRNP70, RNPU1Z, RPU1, SNRP70, U1AP1

Chain

initiator methionine:, chain:2-437

Reference Genes

BioGPS Gene:6625 SNRNP70

COSMIC (genes):SNRNP70 SNRNP70

CTD Gene:6625 SNRNP70

dbSNP Gene:6625 SNRNP70

ENSEMBL:ENSG00000104852 SNRNP70

HGNC:11150 SNRNP70

KEGG:hsa:6625 SNRNP70

Monarch:6625 SNRNP70

NCBI Gene:6625 SNRNP70

OMIM:180740 SNRNP70

UCSC:P08621 SNRNP70

Reference Transcript

Other Identifiers

11754463_a_at

11755283_a_at

11759421_at

16863974

201221_PM_s_at

201221_s_at

213121_PM_at

213121_at

3838184

3838186

3838187

3838190

3838191

3838192

3838194

3838195

3838198

3838199

3838200

3838201

3838203

3838204

3838205

3838206

3838207

3838208

3838209

3838210

3838211

3838212

3838213

3838214

3838215

3838216

3838217

3838218

3838222

3838223

3838224

3838225

3838226

3838227

3838228

3838237

40875_s_at

6625

8030199

87370_at

A_14_P105747

A_23_P4902

A_23_P4909

GE79537

GO:0000398

GO:0003676

GO:0003723

GO:0003729

GO:0005515

GO:0005634

GO:0005654

GO:0005681

GO:0005685

GO:0006397

GO:0016071

GO:0016607

GO:0030619

GO:0043226

GO:0043462

GO:0043484

GO:0048026

GO:0061084

GO:0071004

GO:1904715

GO:1990904

HMNXSV003024985

Hs.174051.1.S1_3p_at

ILMN_1683049

ILMN_1732053

ILMN_2380839

PH_hs_0010437

TC19000724.hg

TC19002196.hg

TC19002197.hg

X04654_s_at

g4507118_3p_a_at

g4507118_3p_s_at

Participates

as a component of

U1 snRNP [nucleoplasm] (Homo sapiens)

Inferred To

Ghost homologue of SNRNP70 [nucleoplasm] (Gallus gallus)

Snrnp70 [nucleoplasm] (Mus musculus)

Snrnp70 [nucleoplasm] (Rattus norvegicus)

snrnp70 [nucleoplasm] (Danio rerio)

snrnp70 [nucleoplasm] (Dictyostelium discoideum)

snrnp70 [nucleoplasm] (Xenopus tropicalis)

usp101 [nucleoplasm] (Schizosaccharomyces pombe)

SNP1 [nucleoplasm] (Saccharomyces cerevisiae)

SNRNP70 [nucleoplasm] (Bos taurus)

SNRNP70 [nucleoplasm] (Canis familiaris)

SNRNP70 [nucleoplasm] (Plasmodium falciparum)

SNRNP70 [nucleoplasm] (Sus scrofa)

snRNP-U1-70K [nucleoplasm] (Drosophila melanogaster)

rnp-7 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001287998.1, NP_003080.2

OpenTargets

ENSG00000104852

ENSEMBL

ENST00000598441, ENST00000595231, ENST00000221448, ENST00000401730, ENSP00000468952, ENSP00000221448, ENST00000601065, ENSP00000471006, ENSP00000385077, ENSP00000472998

HPA

ENSG00000104852-SNRNP70

PRO

P08621

Pharos - Targets

P08621

GlyGen

P08621

PDB

4PJO, 2L5I, 2L5J, 7VPX, 6QX9, 3PGW, 4PKD, 7B0Y, 3CW1

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P14678 SNRPB	4	2xMe-SNRPB [cytosol] (R-HSA-192218) SNRPB [cytosol] (R-HSA-191798) Me2-R108,R112-SNRPB [nucleoplasm] (R-HSA-192213) SNRPB [nucleoplasm] (R-HSA-71896)	0.784	8
UniProt:P62316 SNRPD2	2	SNRPD2 [cytosol] (R-HSA-191810) SNRPD2 [nucleoplasm] (R-HSA-71901)	0.725	7
UniProt:P62306 SNRPF	2	SNRPF [cytosol] (R-HSA-191852) SNRPF [nucleoplasm] (R-HSA-71907)	0.725	7
UniProt:P62318 SNRPD3	3	2xMe-SNRPD3 [cytosol] (R-HSA-191781) 2xMe-SNRPD3 [nucleoplasm] (R-HSA-192219) SNRPD3 [nucleoplasm] (R-HSA-71903)	0.643	6
UniProt:P62314 SNRPD1	3	2xMe-SNRPD1 [cytosol] (R-HSA-192217) SNRPD1 [cytosol] (R-HSA-191890) 2xMe-SNRPD1 [nucleoplasm] (R-HSA-192215)	0.643	6
UniProt:P62304 SNRPE	2	SNRPE [cytosol] (R-HSA-191782) SNRPE [nucleoplasm] (R-HSA-71905)	0.643	7
UniProt:Q09161 NCBP1	2	NCBP1 [nucleoplasm] (R-HSA-51469) NCBP1 [cytosol] (R-HSA-162459)	0.643	6
UniProt:Q07955 SRSF1	1	SRSF1 [nucleoplasm] (R-HSA-72031)	0.604	5
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:Q6PKG0 LARP1	1	LARP1 [cytosol] (R-HSA-9760421)	0.527	4
UniProt:Q9Y2W1 THRAP3	1	THRAP3 [nucleoplasm] (R-HSA-8932115)	0.527	3
UniProt:P62308 SNRPG	2	SNRPG [cytosol] (R-HSA-191827) SNRPG [nucleoplasm] (R-HSA-71909)	0.527	5
UniProt:Q9UQ35 SRRM2	1	SRRM2 [nucleoplasm] (R-HSA-8865888)	0.527	3
UniProt:O60832 DKC1	1	DKC1 [nucleoplasm] (R-HSA-163102)	0.527	4
UniProt:Q96RS0 TGS1	2	TGS1 [cytosol] (R-HSA-192209) TGS1 [nucleoplasm] (R-HSA-400176)	0.527	3
UniProt:Q9NPE3 NOP10	1	NOP10 [nucleoplasm] (R-HSA-6790665)	0.527	2
UniProt:Q9H814 PHAX	2	PHAX [cytosol] (R-HSA-191804) PHAX [nucleoplasm] (R-HSA-191803)	0.527	4

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