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SACM1L [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-1604637
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Synonyms
KIAA0851
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Phospholipid metabolism (Homo sapiens)
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the ER membrane (Homo sapiens)
PI4P is dephosphorylated to PI by SACM1L at the ER membrane (Homo sapiens)
SACM1L [endoplasmic reticulum membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9NTJ5 SACM1L
Gene Names
SACM1L, KIAA0851, SAC1
Chain
chain:1-587
Reference Genes
BioGPS Gene:22908 SACM1L
COSMIC (genes):SACM1L SACM1L
CTD Gene:22908 SACM1L
dbSNP Gene:22908 SACM1L
ENSEMBL:ENSG00000211456 SACM1L
ENSEMBL_homo_sapiens_GENE:ENSG00000211456.14 SACM1L
HGNC:17059 SACM1L
KEGG Gene (Homo sapiens):22908 SACM1L
Monarch:22908 SACM1L
NCBI Gene:22908 SACM1L
OMIM:606569 SACM1L
UCSC:Q9NTJ5 SACM1L
Reference Transcript
RefSeq:XM_011533500.2 SACM1L
RefSeq:NM_001319073.1 SACM1L
RefSeq:NM_014016.4 SACM1L
RefSeq:NM_001319072.1 SACM1L
Other Identifiers
11741011_a_at
11747673_a_at
11755387_a_at
16940110
202797_PM_at
202797_at
22908
2620686
2620687
2620689
2620690
2620691
2620695
2620696
2620699
2620700
2620701
2620702
2620703
2620706
2620707
2620710
2620713
2620714
2620715
2620716
2620717
2620721
2620722
36511_at
8079346
A_14_P100053
A_23_P212383
GE53539
GO:0000139
GO:0003824
GO:0004438
GO:0005515
GO:0005783
GO:0005789
GO:0005794
GO:0006629
GO:0006661
GO:0016020
GO:0016787
GO:0016791
GO:0034596
GO:0043226
GO:0043812
GO:0046856
GO:0140268
HMNXSV003021609
HMNXSV003052002
ILMN_1765019
PH_hs_0000594
TC03000250.hg
g7662337_3p_at
Other forms of this molecule
SACM1L [Golgi membrane]
Inferred To
SACM1L [endoplasmic reticulum membrane]
(Bos taurus)
SACM1L [endoplasmic reticulum membrane]
(Canis familiaris)
SACM1L [endoplasmic reticulum membrane]
(Gallus gallus)
SACM1L [endoplasmic reticulum membrane]
(Plasmodium falciparum)
SACM1L [endoplasmic reticulum membrane]
(Schizosaccharomyces pombe)
SACM1L [endoplasmic reticulum membrane]
(Sus scrofa)
Sacm1l [endoplasmic reticulum membrane]
(Mus musculus)
Sacm1l [endoplasmic reticulum membrane]
(Rattus norvegicus)
sac1 [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Sac1 [endoplasmic reticulum membrane]
(Drosophila melanogaster)
SAC1 [endoplasmic reticulum membrane]
(Saccharomyces cerevisiae)
sacm1lb [endoplasmic reticulum membrane]
(Danio rerio)
sac-1 [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
XP_011531802.1
,
NP_001306001.1
,
NP_054735.3
,
NP_001306002.1
OpenTargets
ENSG00000211456
IntEnz
3.1.3.64
GeneCards
Q9NTJ5
HPA
ENSG00000211456-SACM1L
Ensembl
ENST00000438671
,
ENSP00000411966
,
ENSG00000211456
,
ENSP00000373713
,
ENST00000389061
PRO
Q9NTJ5
Pharos - Targets
Q9NTJ5
Interactors (39)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y678 COPG1
4
COPG1 [endoplasmic reticulum membrane]
(R-HSA-6810960)
COPG1 [Golgi membrane]
(R-HSA-6808747)
COPG1 [transport vesicle]
(R-HSA-6808749)
COPG1 [cytosol]
(R-HSA-199987)
0.677
6
UniProt:O14579 COPE
4
COPE [endoplasmic reticulum membrane]
(R-HSA-6810959)
COPE [Golgi membrane]
(R-HSA-6808743)
COPE [transport vesicle]
(R-HSA-6808745)
COPE [cytosol]
(R-HSA-199969)
0.643
3
UniProt:Q96BA8 CREB3L1
7
CREB3L1 [Golgi membrane]
(R-HSA-8874155)
CREB3L1(427-519) [Golgi membrane]
(R-HSA-8874139)
CREB3L1(1-426) [Golgi membrane]
(R-HSA-8874153)
CREB3L1 [endoplasmic reticulum membrane]
(R-HSA-8874157)
CREB3L1(1-375) [cytosol]
(R-HSA-8874215)
CREB3L1(376-426) [Golgi membrane]
(R-HSA-8874213)
CREB3L1(1-375) [nucleoplasm]
(R-HSA-8874222)
0.601
6
UniProt:O00590 ACKR2
1
ACKR2 [plasma membrane]
(R-HSA-443955)
0.556
3
UniProt:O95197-3 RTN3
0.556
3
UniProt:P11912 CD79A
2
p-Y188,Y199-CD79A [plasma membrane]
(R-HSA-983539)
CD79A [plasma membrane]
(R-HSA-197154)
0.556
3
UniProt:Q7Z5P4 HSD17B13
1
HSD17B13 [cytosol]
(R-HSA-8862029)
0.556
3
IntAct:EBI-23194662 CCSB ORF ID
0.556
3
UniProt:Q9GZY8-5 MFF
0.556
3
UniProt:Q8TDT2 GP152
0.556
3
UniProt:Q8TDV0 GP151
0.556
3
UniProt:Q9Y320 TMX2
0.556
3
UniProt:Q9NQQ7-3 Q9NQQ73
0.556
3
UniProt:Q6ZMZ0 RNF19B
1
RNF19B [cytosol]
(R-HSA-975969)
0.556
3
UniProt:Q2M2E3 ODFP4
0.556
3
UniProt:Q5SR56 MF14B
0.556
3
UniProt:Q9BS91 S35A5
0.556
3
UniProt:Q9NY72 SCN3B
1
SCN3B [plasma membrane]
(R-HSA-197921)
0.556
3
UniProt:P31513 FMO3
6
FMO3 M66I [endoplasmic reticulum membrane]
(R-HSA-5603010)
FMO3 E32K [endoplasmic reticulum membrane]
(R-HSA-5602848)
FMO3 R492W [endoplasmic reticulum membrane]
(R-HSA-5602849)
FMO3 N61S [endoplasmic reticulum membrane]
(R-HSA-5602964)
FMO3 P153L [endoplasmic reticulum membrane]
(R-HSA-5602837)
FMO3 [endoplasmic reticulum membrane]
(R-HSA-54929)
0.556
3
UniProt:Q8N5M9 JAGN1
0.556
3
UniProt:Q49AM1 MTEF2
0.556
3
UniProt:Q9NRX6 KISHB
0.556
3
UniProt:O15552 FFAR2
1
FFAR2 [plasma membrane]
(R-HSA-443944)
0.556
3
UniProt:Q14973 SLC10A1
1
SLC10A1 [plasma membrane]
(R-HSA-194116)
0.556
3
UniProt:Q3SXY8 ARL13B
8
PolyUb-Misfolded ARL13B [lysosomal lumen]
(R-HSA-9660004)
PolyUb-Misfolded ARL13B [cytosol]
(R-HSA-9641129)
Ub-Misfolded ARL13B [cytosol]
(R-HSA-9641119)
Misfolded ARL13B [cytosol]
(R-HSA-9640110)
Misfolded ARL13B [cilium]
(R-HSA-9640116)
ARL13B [cilium]
(R-HSA-5618181)
PolyUb-Misfolded ARL13B [late endosome lumen]
(R-HSA-9659986)
ARL13B [plasma membrane]
(R-HSA-9716787)
0.556
3
UniProt:Q15125 EBP
1
EBP [endoplasmic reticulum membrane]
(R-HSA-195697)
0.556
3
UniProt:P30825 SLC7A1
1
SLC7A1 [plasma membrane]
(R-HSA-375771)
0.556
3
UniProt:Q3KNW5 SLC10A6
1
SLC10A6 [plasma membrane]
(R-HSA-433091)
0.556
3
UniProt:Q9Y394 DHRS7
0.556
3
UniProt:Q13520 AQP6
1
AQP6 [transport vesicle membrane]
(R-HSA-431741)
0.556
3
UniProt:Q5T4F4 ZFY27
0.556
3
UniProt:Q92544 TM9S4
0.527
2
UniProt:Q8IVM8 S22A9
0.527
2
UniProt:P53621 COPA
4
COPA [endoplasmic reticulum membrane]
(R-HSA-6810953)
COPA [Golgi membrane]
(R-HSA-6808731)
COPA [transport vesicle]
(R-HSA-6808732)
COPA [cytosol]
(R-HSA-199978)
0.527
2
UniProt:Q92633 LPAR1
1
LPAR1 [plasma membrane]
(R-HSA-419354)
0.527
2
UniProt:P58658 EVA1C
0.527
3
UniProt:Q9H244 P2RY12
1
P2RY12 [plasma membrane]
(R-HSA-391959)
0.527
2
UniProt:P0DTD1-PRO_0000449629 REP
0.488
2
UniProt:P13569 CFTR
17
PolyUb-CFTR [clathrin-coated endocytic vesicle membrane]
(R-HSA-8869104)
PolyUb-CFTR [plasma membrane]
(R-HSA-8867595)
CFTR [lysosomal membrane]
(R-HSA-5627279)
CFTR [Golgi-associated vesicle membrane]
(R-HSA-5627079)
CFTR [endosome membrane]
(R-HSA-6782965)
PolyUb-CFTR [endosome membrane]
(R-HSA-6782976)
CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866834)
ub-CFTR F508del [cytosol]
(R-HSA-8866838)
ub-CFTR F508del [endoplasmic reticulum membrane]
(R-HSA-8866842)
CFTR G542* [plasma membrane]
(R-HSA-5678986)
CFTR G551D [plasma membrane]
(R-HSA-5678977)
CFTR W1282* [plasma membrane]
(R-HSA-5678976)
CFTR F508del [plasma membrane]
(R-HSA-5678978)
CFTR N1303K [plasma membrane]
(R-HSA-5678983)
CFTR [plasma membrane]
(R-HSA-383188)
CFTR [endoplasmic reticulum membrane]
(R-HSA-8866837)
misfolded CFTR [endoplasmic reticulum membrane]
(R-HSA-8868730)
0.483
5
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