Reactome | p-Y188,Y199-CD79A [plasma membrane]

p-Y188,Y199-CD79A [plasma membrane]

Stable Identifier

R-HSA-983539

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

CD79A (Ig-alpha) with phosphotyrosine-188 and phsophotyrosine-199, C79A_HUMAN, CD79A

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P11912 CD79A

Gene Names

CD79A, IGA, MB1

Chain

signal peptide:1-32, chain:33-226

Reference Genes

BioGPS Gene:973 CD79A

COSMIC (genes):CD79A CD79A

CTD Gene:973 CD79A

dbSNP Gene:973 CD79A

ENSEMBL:ENSG00000105369 CD79A

ENSEMBL_homo_sapiens_GENE:ENSG00000105369 CD79A

HGNC:1698 CD79A

KEGG Gene (Homo sapiens):973 CD79A

Monarch:973 CD79A

NCBI Gene:973 CD79A

OMIM:112205 CD79A

UCSC:P11912 CD79A

Reference Transcript

Other Identifiers

0006840132

0007000204

11719716_a_at

11741089_x_at

11754069_a_at

1555779_a_at

16862604

1CV9

205049_s_at

38017_at

38018_g_at

3834503

3834504

3834507

3834508

3834509

3834511

3834513

3834514

3834515

3834516

3834517

3834518

8029136

973

A_23_P107735

AAA20495

AAA59556

AAA59557

AAA60270

AAB20812

AAB23558

AAC60653

BAD97091

CAA31802

CAA58523

CAB000019

CCDS12589

CCDS46088

CD79A

CD79A-201

CD79A-202

ENSG00000105369

ENSP00000221972

ENSP00000400605

ENST00000221972

ENST00000444740

EntrezGene:973

g4502684_3p_a_at

GE58879

GO:0002250

GO:0002376

GO:0003674

GO:0004888

GO:0005515

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005768

GO:0005771

GO:0005886

GO:0007165

GO:0007166

GO:0008150

GO:0008283

GO:0009897

GO:0016020

GO:0016021

GO:0019815

GO:0022607

GO:0030154

GO:0030183

GO:0031410

GO:0032991

GO:0042100

GO:0042113

GO:0042803

GO:0043226

GO:0045121

GO:0048856

GO:0050853

GO:0051289

GO:0065003

HGNC:1698

Hs2.79630.3.S1_3p_s_at

ILMN_1659227

ILMN_1734878

ILMN_2410371

IPR003110

IPR003598

IPR003599

IPR007110

IPR013151

IPR013783

IPR036179

LRG_42

M0QX61

MIM:112205

MIM:613501

NM_001783

NM_021601

NP_001774

NP_067612

PF00047

PF02189

PH_hs_0004606

SM00077

SM00408

SM00409

TC19000588.hg

U05259_rna1_at

uc002oru.4

uc002orv.3

UPI000002A519

UPI000011398E

Participant Of

hasComponent

p-BCR [plasma membrane]

Other forms of this molecule

CD79A [plasma membrane]

Inferred To

phospho-p-Y188,Y199-CD79A [plasma membrane] (Bos taurus)

phospho-p-Y188,Y199-CD79A [plasma membrane] (Canis familiaris)

phospho-p-Y188,Y199-CD79A [plasma membrane] (Danio rerio)

phospho-p-Y188,Y199-CD79A [plasma membrane] (Mus musculus)

phospho-p-Y188,Y199-CD79A [plasma membrane] (Rattus norvegicus)

phospho-p-Y188,Y199-CD79A [plasma membrane] (Sus scrofa)

phospho-p-Y188,Y199-CD79A [plasma membrane] (Xenopus tropicalis)

Homologues of p-Y188,Y199-CD79A [plasma membrane] (Rattus norvegicus)

Ghost homologue of p-Y188,Y199-CD79A [plasma membrane] (Gallus gallus)

Ghost homologue of p-Y188,Y199-CD79A [plasma membrane] (Taeniopygia guttata)

Modified Residues

Name

O4'-phospho-L-tyrosine at 188

Coordinate

188

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Name

O4'-phospho-L-tyrosine at 199

Coordinate

199

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_067612.1, NP_001774.1

OpenTargets

ENSG00000105369

GeneCards

P11912

PRO

P11912

Orphanet

18956

PDB

1CV9

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09601 HMOX1	1	HMOX1 [endoplasmic reticulum membrane] (R-HSA-189395)	0.488	2
UniProt:P11686 SFTPC	9	pro-SFTPC P30L [endoplasmic reticulum membrane] (R-HSA-5688365) pro-SFTPC P115L [endoplasmic reticulum membrane] (R-HSA-5688352) pro-SFTPC [endoplasmic reticulum membrane] (R-HSA-5683842) pro-SFTPC [multivesicular body lumen] (R-HSA-5685298) SFTPC [extracellular region] (R-HSA-5683685) SFTPC [clathrin-coated endocytic vesicle] (R-HSA-5686342) SFTPC [lamellar body] (R-HSA-5683717) SFTPC(24-58) [multivesicular body lumen] (R-HSA-5685899) SFTPC(59-197) [multivesicular body lumen] (R-HSA-5685871)	0.488	2
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.488	2
UniProt:Q9Y5Z9 UBIAD1	1	UBIAD1 [endoplasmic reticulum membrane] (R-HSA-2980965)	0.488	2
UniProt:P08034 GJB1	2	GJB1 [endoplasmic reticulum membrane] (R-HSA-190656) GJB1 [endoplasmic reticulum-Golgi intermediate compartment] (R-HSA-190636)	0.488	2
UniProt:Q7L5A8 FA2H	1	FA2H [endoplasmic reticulum membrane] (R-HSA-5693771)	0.488	2
UniProt:O95406 CNIH1	3	CNIH1 [ER to Golgi transport vesicle membrane] (R-HSA-5689776) CNIH1 [endoplasmic reticulum membrane] (R-HSA-5689439) CNIH1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689778)	0.488	2
UniProt:Q9H1C4 UNC93B1	4	UNC93B1 [endoplasmic reticulum membrane] (R-HSA-1678930) UNC93B1 [Golgi membrane] (R-HSA-1679064) UNC93B1 P345fs* [endoplasmic reticulum membrane] (R-HSA-9628866) UNC93B1 G261fs* [endoplasmic reticulum membrane] (R-HSA-9628869)	0.488	2
UniProt:Q9H2H9 SLC38A1	1	SLC38A1 [plasma membrane] (R-HSA-212663)	0.488	4
UniProt:P48065 SLC6A12	1	SLC6A12 [plasma membrane] (R-HSA-351969)	0.488	2
UniProt:O15155 BET1	3	BET1 [transport vesicle] (R-HSA-6808719) BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142) BET1 [Golgi membrane] (R-HSA-6807743)	0.488	2
UniProt:O76024 WFS1	3	p-WFS1 [endoplasmic reticulum lumen] (R-HSA-8956998) WFS1 [endoplasmic reticulum membrane] (R-HSA-535474) WFS1 [endoplasmic reticulum lumen] (R-HSA-8956747)	0.488	2
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.488	2
UniProt:O14843 FFAR3	1	FFAR3 [plasma membrane] (R-HSA-443951)	0.488	2
UniProt:Q9BRI3 SLC30A2	2	SLC30A2 [synaptic vesicle membrane] (R-HSA-4084714) SLC30A2 [endosome membrane] (R-HSA-435363)	0.488	2
UniProt:P07204 THBD	1	THBD [plasma membrane] (R-HSA-141030)	0.488	2
UniProt:Q9NTJ5 SACM1L	2	SACM1L [endoplasmic reticulum membrane] (R-HSA-1604637) SACM1L [Golgi membrane] (R-HSA-1806242)	0.488	2
UniProt:Q8WVV5 BTN2A2	1	BTN2A2 [plasma membrane] (R-HSA-8851047)	0.488	2
UniProt:Q8IY26 PLPP6	1	PLPP6 [plasma membrane] (R-HSA-8952144)	0.488	2
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.488	2
UniProt:Q969S0 SLC35B4	1	SLC35B4 [Golgi membrane] (R-HSA-742365)	0.488	2
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.488	2
UniProt:P46695 IER3	1	IER3 [cytosol] (R-HSA-6811515)	0.488	2
UniProt:P08100 RHO	8	RHO [Golgi-associated vesicle membrane] (R-HSA-5623406) RHO [ciliary membrane] (R-HSA-5623404) RHO [Golgi membrane] (R-HSA-5623400) RHO [photoreceptor disc membrane] (R-HSA-419802) 11c-retinyl-RHO [photoreceptor disc membrane] (R-HSA-5205900) at-retinyl-RHO [photoreceptor disc membrane] (R-HSA-5205901) p-S334,338,343-at-retinyl-RHO [photoreceptor disc membrane] (R-HSA-5205903) p-S334,338,343-RHO [photoreceptor disc membrane] (R-HSA-2581504)	0.488	2
UniProt:Q9Y6X1 SERP1	2	SERP1 [endoplasmic reticulum membrane] (R-HSA-381045) SERP1 [cytosol] (R-HSA-5250574)	0.488	2
UniProt:Q9UKG4 SLC13A4	1	SLC13A4 [plasma membrane] (R-HSA-433098)	0.488	4
UniProt:Q86YT5 SLC13A5	1	SLC13A5 [plasma membrane] (R-HSA-433135)	0.488	2
UniProt:Q15836 VAMP3	6	VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [clathrin-coated vesicle membrane] (R-HSA-8869130)	0.488	2
UniProt:Q92685 ALG3	5	ALG3 M157K [endoplasmic reticulum membrane] (R-HSA-4720484) ALG3 R171Q [endoplasmic reticulum membrane] (R-HSA-4720470) ALG3 G118D [endoplasmic reticulum membrane] (R-HSA-4720468) ALG3 W71R [endoplasmic reticulum membrane] (R-HSA-4720466) ALG3 [endoplasmic reticulum membrane] (R-HSA-449287)	0.488	2