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CD226 [plasma membrane]
Stable Identifier
R-HSA-197562
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
CD226 antigen precursor, C226_HUMAN
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
Nectin 2 binds CD226 (Homo sapiens)
CD226 [plasma membrane] (Homo sapiens)
CD226 bound to Nectin 2 [plasma membrane] (Homo sapiens)
CD226 [plasma membrane] (Homo sapiens)
PVR binds CD226 (Homo sapiens)
CD226 [plasma membrane] (Homo sapiens)
CD226:PVR [plasma membrane] (Homo sapiens)
CD226 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15762 CD226
Gene Names
CD226, DNAM1
Chain
signal peptide:1-18, chain:19-336
Reference Genes
BioGPS Gene:10666 CD226
COSMIC (genes):CD226 CD226
CTD Gene:10666 CD226
dbSNP Gene:10666 CD226
ENSEMBL:ENSG00000150637 CD226
HGNC:16961 CD226
KEGG:hsa:10666 CD226
Monarch:10666 CD226
NCBI Gene:10666 CD226
OMIM:605397 CD226
UCSC:Q15762 CD226
Reference Transcript
RefSeq:NM_001303618.1 CD226
RefSeq:XM_005266642.3 CD226
RefSeq:NM_006566.3 CD226
Other Identifiers
10666
11737251_at
11756610_a_at
16855810
207315_PM_at
207315_at
33575_at
3812382
3812384
3812386
3812387
3812388
3812389
3812390
3812391
3812392
3812393
3812394
3812395
3812402
3812403
3812404
3812405
3812416
3812417
3812419
3812420
3812421
3812422
3812423
3812424
3812425
42531_at
8023757
A_23_P78330
A_32_P125917
A_32_P30434
A_33_P3413558
GE474446
GE819720
GO:0002729
GO:0002860
GO:0002891
GO:0005178
GO:0005515
GO:0005886
GO:0007155
GO:0007165
GO:0008037
GO:0009897
GO:0009986
GO:0016020
GO:0019901
GO:0032729
GO:0033005
GO:0042802
GO:0045121
GO:0045954
GO:0050839
GO:0050862
GO:0060369
HMNXSV003047031
HMNXSV003055961
ILMN_1687825
PH_hs_0006961
PH_hs_0024112
TC18000566.hg
U56102_at
g5729807_3p_at
Participates
as a component of
CD226 bound to Nectin 2 [plasma membrane] (Homo sapiens)
CD226:PVR [plasma membrane] (Homo sapiens)
as an input of
Nectin 2 binds CD226 (Homo sapiens)
PVR binds CD226 (Homo sapiens)
Inferred To
CD226 [plasma membrane]
(Canis familiaris)
CD226 [plasma membrane]
(Gallus gallus)
CD226 [plasma membrane]
(Sus scrofa)
cd226 [plasma membrane]
(Danio rerio)
Cd226 [plasma membrane]
(Mus musculus)
Cd226 [plasma membrane]
(Rattus norvegicus)
Cross References
Guide to Pharmacology - Targets
3295
ENSEMBL
ENST00000280200
,
ENSP00000280200
,
ENST00000582621
,
ENSG00000150637
,
ENSP00000461947
OpenTargets
ENSG00000150637
GeneCards
CD226
HPA
ENSG00000150637-CD226
PRO
Q15762
Pharos - Targets
Q15762
GlyGen
Q15762
PDB
6O3O
,
6ISB
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15151 PVR
1
PVR [plasma membrane]
(R-HSA-420600)
0.676
3
UniProt:Q15762 CD226
1
CD226 [plasma membrane]
(R-HSA-197562)
0.609
2
UniProt:Q495A1 TIGIT
0.563
4
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