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About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
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ReactomeFIViz
Developer's Zone
Graph Database
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OA [mitochondrial matrix]
Stable Identifier
R-ALL-113587
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Oxaloacetate, OAA, oxaloacetic acid, Oxalacetic acid, 2-oxobutanedioic acid, Oxosuccinic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Aspartate and asparagine metabolism (Bos taurus)
GOT2 dimer deaminates L-Asp (Bos taurus)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Bos taurus)
GOT2 transaminates oxaloacetate and glutamate (Bos taurus)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Bos taurus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Bos taurus)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
GOT2 transaminates oxaloacetate and glutamate (Bos taurus)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Bos taurus)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Bos taurus)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Bos taurus)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Bos taurus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Bos taurus)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Bos taurus)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Bos taurus)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Bos taurus)
OA [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Aspartate and asparagine metabolism (Caenorhabditis elegans)
GOT2 dimer deaminates L-Asp (Caenorhabditis elegans)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Caenorhabditis elegans)
GOT2 transaminates oxaloacetate and glutamate (Caenorhabditis elegans)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Caenorhabditis elegans)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Caenorhabditis elegans)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
GOT2 transaminates oxaloacetate and glutamate (Caenorhabditis elegans)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Caenorhabditis elegans)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Caenorhabditis elegans)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism and Citric Acid (TCA) cycle (Caenorhabditis elegans)
Citric acid cycle (TCA cycle) (Caenorhabditis elegans)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Caenorhabditis elegans)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Caenorhabditis elegans)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Caenorhabditis elegans)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Caenorhabditis elegans)
OA [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Aspartate and asparagine metabolism (Canis familiaris)
GOT2 dimer deaminates L-Asp (Canis familiaris)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Canis familiaris)
GOT2 transaminates oxaloacetate and glutamate (Canis familiaris)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Canis familiaris)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Canis familiaris)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
GOT2 transaminates oxaloacetate and glutamate (Canis familiaris)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Canis familiaris)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Canis familiaris)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Canis familiaris)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Canis familiaris)
Pyruvate metabolism and Citric Acid (TCA) cycle (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Canis familiaris)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Canis familiaris)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Canis familiaris)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Canis familiaris)
OA [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Aspartate and asparagine metabolism (Danio rerio)
GOT2 dimer deaminates L-Asp (Danio rerio)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Danio rerio)
GOT2 transaminates oxaloacetate and glutamate (Danio rerio)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Danio rerio)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Danio rerio)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
GOT2 transaminates oxaloacetate and glutamate (Danio rerio)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Danio rerio)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Danio rerio)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Danio rerio)
Pyruvate metabolism and Citric Acid (TCA) cycle (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Danio rerio)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Danio rerio)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Danio rerio)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Danio rerio)
OA [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Aspartate and asparagine metabolism (Dictyostelium discoideum)
GOT2 dimer deaminates L-Asp (Dictyostelium discoideum)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Dictyostelium discoideum)
GOT2 transaminates oxaloacetate and glutamate (Dictyostelium discoideum)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Dictyostelium discoideum)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Dictyostelium discoideum)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
GOT2 transaminates oxaloacetate and glutamate (Dictyostelium discoideum)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Dictyostelium discoideum)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism and Citric Acid (TCA) cycle (Dictyostelium discoideum)
Citric acid cycle (TCA cycle) (Dictyostelium discoideum)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Dictyostelium discoideum)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Dictyostelium discoideum)
OA [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Aspartate and asparagine metabolism (Drosophila melanogaster)
GOT2 dimer deaminates L-Asp (Drosophila melanogaster)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Drosophila melanogaster)
GOT2 transaminates oxaloacetate and glutamate (Drosophila melanogaster)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Drosophila melanogaster)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Drosophila melanogaster)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
GOT2 transaminates oxaloacetate and glutamate (Drosophila melanogaster)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Drosophila melanogaster)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Drosophila melanogaster)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism and Citric Acid (TCA) cycle (Drosophila melanogaster)
Citric acid cycle (TCA cycle) (Drosophila melanogaster)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Drosophila melanogaster)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Drosophila melanogaster)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Drosophila melanogaster)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Drosophila melanogaster)
OA [mitochondrial matrix]
Metabolism (Gallus gallus)
Amino acid metabolism (Gallus gallus)
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
OA [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
OA [mitochondrial matrix]
Carbohydrate metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] (Gallus gallus)
OA [mitochondrial matrix]
oxaloacetate + NADH + H+ <=> malate + NAD+ (Gallus gallus)
OA [mitochondrial matrix]
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
OA [mitochondrial matrix]
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
OA [mitochondrial matrix]
Lipid metabolism (Gallus gallus)
oxaloacetate + NADH + H+ <=> malate + NAD+ (Gallus gallus)
OA [mitochondrial matrix]
The tricarboxylic acid cycle (Gallus gallus)
acetyl-CoA + H2O + oxaloacetate => citrate + CoA (Gallus gallus)
OA [mitochondrial matrix]
malate + NAD+ <=> oxaloacetate + NADH + H+ (Gallus gallus)
OA [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Aspartate and asparagine metabolism (Homo sapiens)
GOT2 dimer deaminates L-Asp (Homo sapiens)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Homo sapiens)
GOT2 transaminates oxaloacetate and glutamate (Homo sapiens)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Homo sapiens)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Homo sapiens)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
GOT2 transaminates oxaloacetate and glutamate (Homo sapiens)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Homo sapiens)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Homo sapiens)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Homo sapiens)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Homo sapiens)
Pyruvate metabolism and Citric Acid (TCA) cycle (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Homo sapiens)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Homo sapiens)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Homo sapiens)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Homo sapiens)
OA [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Aspartate and asparagine metabolism (Mus musculus)
GOT2 dimer deaminates L-Asp (Mus musculus)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Mus musculus)
GOT2 transaminates oxaloacetate and glutamate (Mus musculus)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Mus musculus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Mus musculus)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
GOT2 transaminates oxaloacetate and glutamate (Mus musculus)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Mus musculus)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Mus musculus)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Mus musculus)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Mus musculus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Mus musculus)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Mus musculus)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Mus musculus)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Mus musculus)
OA [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Aspartate and asparagine metabolism (Plasmodium falciparum)
GOT2 dimer deaminates L-Asp (Plasmodium falciparum)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Plasmodium falciparum)
GOT2 transaminates oxaloacetate and glutamate (Plasmodium falciparum)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Plasmodium falciparum)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Plasmodium falciparum)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Plasmodium falciparum)
Glucose metabolism (Plasmodium falciparum)
Gluconeogenesis (Plasmodium falciparum)
GOT2 transaminates oxaloacetate and glutamate (Plasmodium falciparum)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Plasmodium falciparum)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Plasmodium falciparum)
Pyruvate metabolism and Citric Acid (TCA) cycle (Plasmodium falciparum)
Citric acid cycle (TCA cycle) (Plasmodium falciparum)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Plasmodium falciparum)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Plasmodium falciparum)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Plasmodium falciparum)
OA [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Aspartate and asparagine metabolism (Rattus norvegicus)
GOT2 dimer deaminates L-Asp (Rattus norvegicus)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Rattus norvegicus)
GOT2 transaminates oxaloacetate and glutamate (Rattus norvegicus)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Rattus norvegicus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
GOT2 transaminates oxaloacetate and glutamate (Rattus norvegicus)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Rattus norvegicus)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Rattus norvegicus)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Rattus norvegicus)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism and Citric Acid (TCA) cycle (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Rattus norvegicus)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Rattus norvegicus)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Rattus norvegicus)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Rattus norvegicus)
OA [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Aspartate and asparagine metabolism (Saccharomyces cerevisiae)
GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Saccharomyces cerevisiae)
GOT2 transaminates oxaloacetate and glutamate (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Saccharomyces cerevisiae)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
GOT2 transaminates oxaloacetate and glutamate (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism and Citric Acid (TCA) cycle (Saccharomyces cerevisiae)
Citric acid cycle (TCA cycle) (Saccharomyces cerevisiae)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Saccharomyces cerevisiae)
OA [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Aspartate and asparagine metabolism (Schizosaccharomyces pombe)
GOT2 dimer deaminates L-Asp (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Schizosaccharomyces pombe)
GOT2 transaminates oxaloacetate and glutamate (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Schizosaccharomyces pombe)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
GOT2 transaminates oxaloacetate and glutamate (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism and Citric Acid (TCA) cycle (Schizosaccharomyces pombe)
Citric acid cycle (TCA cycle) (Schizosaccharomyces pombe)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Schizosaccharomyces pombe)
OA [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Aspartate and asparagine metabolism (Sus scrofa)
GOT2 dimer deaminates L-Asp (Sus scrofa)
OA [mitochondrial matrix]
Glutamate and glutamine metabolism (Sus scrofa)
GOT2 transaminates oxaloacetate and glutamate (Sus scrofa)
OA [mitochondrial matrix]
Glyoxylate metabolism and glycine degradation (Sus scrofa)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Sus scrofa)
OA [mitochondrial matrix]
Metabolism of carbohydrates (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
GOT2 transaminates oxaloacetate and glutamate (Sus scrofa)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Sus scrofa)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Sus scrofa)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Sus scrofa)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Sus scrofa)
Pyruvate metabolism and Citric Acid (TCA) cycle (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Sus scrofa)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Sus scrofa)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Sus scrofa)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Sus scrofa)
OA [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of carbohydrates (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
MDH2 reduces OA to MAL (Xenopus tropicalis)
OA [mitochondrial matrix]
PC catalyzes the carboxylation of PYR to form OA (Xenopus tropicalis)
OA [mitochondrial matrix]
PCK2 phosphorylates OA to yield PEP (Xenopus tropicalis)
OA [mitochondrial matrix]
The citric acid (TCA) cycle and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism and Citric Acid (TCA) cycle (Xenopus tropicalis)
Citric acid cycle (TCA cycle) (Xenopus tropicalis)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Xenopus tropicalis)
OA [mitochondrial matrix]
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Xenopus tropicalis)
OA [mitochondrial matrix]
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Xenopus tropicalis)
OA [mitochondrial matrix]
MDH2 reduces OA to MAL (Xenopus tropicalis)
OA [mitochondrial matrix]
External Reference Information
External Reference
oxaloacetate(2-) [ChEBI:16452]
Participates
as an input of
oxaloacetate + GTP => phosphoenolpyruvate + GDP + CO2 [mitochondrial matrix] (Gallus gallus)
oxaloacetate + glutamate <=> aspartate + alpha-ketoglutarate (2-oxoglutarate) (Gallus gallus)
oxaloacetate + NADH + H+ <=> malate + NAD+ (Gallus gallus)
acetyl-CoA + H2O + oxaloacetate => citrate + CoA (Gallus gallus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Saccharomyces cerevisiae)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Schizosaccharomyces pombe)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Dictyostelium discoideum)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Caenorhabditis elegans)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Drosophila melanogaster)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Gallus gallus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Xenopus tropicalis)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Danio rerio)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Sus scrofa)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Bos taurus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Canis familiaris)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Rattus norvegicus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Mus musculus)
FAHD1:Zn2+ dimer hydrolyses OA to PYR (Homo sapiens)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Plasmodium falciparum)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Saccharomyces cerevisiae)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Schizosaccharomyces pombe)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Dictyostelium discoideum)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Caenorhabditis elegans)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Drosophila melanogaster)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Gallus gallus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Danio rerio)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Sus scrofa)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Bos taurus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Canis familiaris)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Rattus norvegicus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Mus musculus)
PXLP-K279-GOT2 dimer transaminates 4-OH-L-glutamate to 4-hydroxy-2-oxoglutarate (HOG) (Homo sapiens)
PCK2 phosphorylates OA to yield PEP (Dictyostelium discoideum)
PCK2 phosphorylates OA to yield PEP (Gallus gallus)
PCK2 phosphorylates OA to yield PEP (Xenopus tropicalis)
PCK2 phosphorylates OA to yield PEP (Sus scrofa)
PCK2 phosphorylates OA to yield PEP (Bos taurus)
PCK2 phosphorylates OA to yield PEP (Canis familiaris)
PCK2 phosphorylates OA to yield PEP (Rattus norvegicus)
PCK2 phosphorylates OA to yield PEP (Mus musculus)
PCK2 phosphorylates OA to yield PEP (Homo sapiens)
MDH2 reduces OA to MAL (Plasmodium falciparum)
MDH2 reduces OA to MAL (Saccharomyces cerevisiae)
MDH2 reduces OA to MAL (Schizosaccharomyces pombe)
MDH2 reduces OA to MAL (Caenorhabditis elegans)
MDH2 reduces OA to MAL (Drosophila melanogaster)
MDH2 reduces OA to MAL (Gallus gallus)
MDH2 reduces OA to MAL (Xenopus tropicalis)
MDH2 reduces OA to MAL (Danio rerio)
MDH2 reduces OA to MAL (Sus scrofa)
MDH2 reduces OA to MAL (Bos taurus)
MDH2 reduces OA to MAL (Canis familiaris)
MDH2 reduces OA to MAL (Rattus norvegicus)
MDH2 reduces OA to MAL (Homo sapiens)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Plasmodium falciparum)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Saccharomyces cerevisiae)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Schizosaccharomyces pombe)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Gallus gallus)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Dictyostelium discoideum)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Caenorhabditis elegans)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Drosophila melanogaster)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Xenopus tropicalis)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Danio rerio)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Sus scrofa)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Bos taurus)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Canis familiaris)
MDH2 reduces OA to MAL (Mus musculus)
GOT2 transaminates oxaloacetate and glutamate (Homo sapiens)
GOT2 transaminates oxaloacetate and glutamate (Mus musculus)
GOT2 transaminates oxaloacetate and glutamate (Rattus norvegicus)
GOT2 transaminates oxaloacetate and glutamate (Canis familiaris)
GOT2 transaminates oxaloacetate and glutamate (Bos taurus)
GOT2 transaminates oxaloacetate and glutamate (Sus scrofa)
GOT2 transaminates oxaloacetate and glutamate (Danio rerio)
GOT2 transaminates oxaloacetate and glutamate (Gallus gallus)
GOT2 transaminates oxaloacetate and glutamate (Drosophila melanogaster)
GOT2 transaminates oxaloacetate and glutamate (Caenorhabditis elegans)
GOT2 transaminates oxaloacetate and glutamate (Dictyostelium discoideum)
GOT2 transaminates oxaloacetate and glutamate (Schizosaccharomyces pombe)
GOT2 transaminates oxaloacetate and glutamate (Saccharomyces cerevisiae)
GOT2 transaminates oxaloacetate and glutamate (Plasmodium falciparum)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Homo sapiens)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Mus musculus)
Acetyl-CoA + H2O + Oxaloacetate => Citrate + CoA (Rattus norvegicus)
as an output of
aspartate + alpha-ketoglutarate (2-oxoglutarate) <=> oxaloacetate + glutamate (Gallus gallus)
pyruvate + CO2 + ATP => oxaloacetate + ADP + orthophosphate (Gallus gallus)
malate + NAD+ <=> oxaloacetate + NADH + H+ (Gallus gallus)
PC catalyzes the carboxylation of PYR to form OA (Xenopus tropicalis)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Plasmodium falciparum)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Saccharomyces cerevisiae)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Schizosaccharomyces pombe)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Gallus gallus)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Caenorhabditis elegans)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Drosophila melanogaster)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Xenopus tropicalis)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Danio rerio)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Sus scrofa)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Bos taurus)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Canis familiaris)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Rattus norvegicus)
PC catalyzes the carboxylation of PYR to form OA (Mus musculus)
PC catalyzes the carboxylation of PYR to form OA (Homo sapiens)
GOT2 dimer deaminates L-Asp (Homo sapiens)
GOT2 dimer deaminates L-Asp (Mus musculus)
GOT2 dimer deaminates L-Asp (Rattus norvegicus)
GOT2 dimer deaminates L-Asp (Canis familiaris)
GOT2 dimer deaminates L-Asp (Bos taurus)
GOT2 dimer deaminates L-Asp (Sus scrofa)
GOT2 dimer deaminates L-Asp (Danio rerio)
GOT2 dimer deaminates L-Asp (Gallus gallus)
GOT2 dimer deaminates L-Asp (Drosophila melanogaster)
GOT2 dimer deaminates L-Asp (Caenorhabditis elegans)
GOT2 dimer deaminates L-Asp (Dictyostelium discoideum)
GOT2 dimer deaminates L-Asp (Schizosaccharomyces pombe)
GOT2 dimer deaminates L-Asp (Saccharomyces cerevisiae)
GOT2 dimer deaminates L-Asp (Plasmodium falciparum)
PC catalyzes the carboxylation of PYR to form OA (Rattus norvegicus)
PC catalyzes the carboxylation of PYR to form OA (Canis familiaris)
PC catalyzes the carboxylation of PYR to form OA (Bos taurus)
PC catalyzes the carboxylation of PYR to form OA (Sus scrofa)
PC catalyzes the carboxylation of PYR to form OA (Danio rerio)
PC catalyzes the carboxylation of PYR to form OA (Drosophila melanogaster)
PC catalyzes the carboxylation of PYR to form OA (Caenorhabditis elegans)
PC catalyzes the carboxylation of PYR to form OA (Schizosaccharomyces pombe)
PC catalyzes the carboxylation of PYR to form OA (Saccharomyces cerevisiae)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Homo sapiens)
(S)-Malate + NAD+ <=> Oxaloacetate + NADH + H+ (Mus musculus)
Other forms of this molecule
OA [peroxisomal matrix]
OA [cytosol]
Cross References
AraCyc
OXALACETIC_ACID
CAS
328-42-7
COMPOUND
C00036
PubChem Compound
164550
,
164550
ZINC
000001532521
KEGG Gene
C00036
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