acetyl-CoA + H2O + oxaloacetate => citrate + CoA

Stable Identifier
R-GGA-373006
Type
Reaction [transition]
Species
Gallus gallus
Compartment
mitochondrial matrix
ReviewStatus
5/5
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acetyl-CoA + H2O + oxaloacetate => citrate + CoA
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Mitochondrial citrate synthase catalyzes the reaction of acetyl-CoA, H2O, and oxaloacetate to form citrate and CoA. The active enzyme is a homodimer (Liao et al. 1991).

Literature References
PubMed ID Title Journal Year
2043641 Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-A resolution

Karpusas, M, Remington, SJ, Liao, DI

Biochemistry 1991
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Catalyst Activity

citrate (Si)-synthase activity of citrate synthase dimer [mitochondrial matrix]

Physical Entity
citrate synthase dimer [mitochondrial matrix] (Gallus gallus)
Activity
citrate (Si)-synthase activity (GO:0004108)
Authored
D'Eustachio, P  (2008-09-10)
Created
D'Eustachio, P  (2008-07-11)
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