acetyl-CoA + H2O + oxaloacetate => citrate + CoA

Stable Identifier
R-GGA-373006
Type
Reaction [transition]
Species
Gallus gallus
Compartment
mitochondrial matrix
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
acetyl-CoA + H2O + oxaloacetate => citrate + CoA
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
Mitochondrial citrate synthase catalyzes the reaction of acetyl-CoA, H2O, and oxaloacetate to form citrate and CoA. The active enzyme is a homodimer (Liao et al. 1991).
Literature References
PubMed ID Title Journal Year
2043641 Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-A resolution

Liao, DI, Karpusas, M, Remington, SJ

Biochemistry 1991
Participants
Input
Output
Participates
as an event of
Catalyst Activity

obsolete citrate (Si)-synthase activity of citrate synthase dimer [mitochondrial matrix]

Physical Entity
citrate synthase dimer [mitochondrial matrix] (Gallus gallus)
Activity
obsolete citrate (Si)-synthase activity (GO:0004108)
Authored
D'Eustachio, P  (2008-09-10)
Created
D'Eustachio, P  (2008-07-11)
Cite Us!