malate + NAD+ <=> oxaloacetate + NADH + H+

Stable Identifier
R-GGA-373047
Type
Reaction [transition]
Species
Gallus gallus
Compartment
mitochondrial matrix
ReviewStatus
5/5
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malate + NAD+ <=> oxaloacetate + NADH + H+
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MDH2 (mitochondrial malate dehydrogenase) catalyzes the reversible reaction of malate and NAD+ to form oxaloacetate and NADH + H+. No chicken enzyme capable of catalyzing this reaction has been identified, although an open reading frame capable of encoding a protein closely similar to authentic human mitochondrial malate dehydrogenase (MDH2) has been identified computationally in the ENSEMBL chicken gene set. This reaction is inferred from its human counterpart.
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Event Information
Reverse Reaction
oxaloacetate + NADH + H+ <=> malate + NAD+ (Gallus gallus)
Catalyst Activity

L-malate dehydrogenase activity of MDH2 [mitochondrial matrix]

Physical Entity
MDH2 [mitochondrial matrix] (Gallus gallus)
Activity
L-malate dehydrogenase activity (GO:0030060)
Inferred From
MDH2 dimer dehydrogenates MAL (Homo sapiens)
Authored
D'Eustachio, P  (2008-09-10)
Created
D'Eustachio, P  (2008-07-12)
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